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CHEM1041 Foundations of chemistry (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	70
Course Co-ordinator	Dr A T L Li, Chemistry < litla@hku.hk >
Teachers Involved	(Dr A M Y Yuen,Chemistry) (Dr A T L Li,Chemistry)
Course Objectives	The course aims to provide students who do not have HKDSE Chemistry or an equivalent background but are interested in exploring Chemistry further, with an understanding of the essential fundamental principles and concepts of chemistry.
Course Contents & Topics	Topic 1: Introduction to Chemistry: Atoms and the Periodic Table Topic 2: Chemical Bonding and Structures Topic 3: Mole concepts and Stoichiometry Topic 4: Types of Chemical Reactions: Acid-base and Redox reactions Topic 5: Introduction to Chemical Equilibrium Topic 6: Introduction to Carbon Compounds
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 demonstrate knowledge and understanding in relation to some chemical vocabulary, terminology and conventions CLO 2 demonstrate knowledge and understanding of chemical stoichiometry, the properties of liquids and solids, the nature of gases, phase changes, chemical bonding and structures, and the nature of chemical equilibria CLO 3 apply the theories and concepts introduced in the course to solve problems, perform calculations, make predictions and rationalize trends CLO 4 organize and present chemical ideas in a clear, logical and coherent way CLO 5 demonstrate awareness and appreciation of the relevant applications of chemistry in society and in everyday life
Pre-requisites (and Co-requisites and Impermissible combinations)	No pre-requisite. This is a bridging course for students without high school chemistry background but are keen to equip themselves with a foundation of chemistry. Students taking this course are expected to work hard by doing active self-reading in order to be able to cope with this course which should not be seen as an easy course (for those with no chemistry background). Not for students with Level 3 or above in HKDSE Chemistry or having taken any level 1 Chemistry course or above or any equivalent Chemistry course
Course Status with Related Major/Minor /Professional Core	2025 Major in Ecology & Biodiversity (Intensive) ( Disciplinary Elective ) 2025 Major in Environmental Science ( Disciplinary Elective ) 2025 Minor in Environmental Science ( Disciplinary Elective ) 2024 Major in Ecology & Biodiversity (Intensive) ( Disciplinary Elective ) 2024 Major in Environmental Science ( Disciplinary Elective ) 2024 Minor in Environmental Science ( Disciplinary Elective ) 2023 Major in Ecology & Biodiversity (Intensive) ( Disciplinary Elective ) 2023 Major in Environmental Science ( Disciplinary Elective ) 2023 Minor in Environmental Science ( Disciplinary Elective ) 2022 Major in Ecology & Biodiversity (Intensive) ( Disciplinary Elective ) 2022 Major in Environmental Science ( Disciplinary Elective ) 2022 Minor in Environmental Science ( Disciplinary Elective ) 2021 Major in Ecology & Biodiversity (Intensive) ( Disciplinary Elective ) 2021 Minor in Environmental Science ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Ecology & Biodiversity (Intensive) < PLO 4 > 2025 Major in Environmental Science < PLO 2 > 2024 Major in Ecology & Biodiversity (Intensive) < PLO 4 > 2024 Major in Environmental Science < PLO 2 > 2023 Major in Ecology & Biodiversity (Intensive) < PLO 4 > 2023 Major in Environmental Science < PLO 2 > 2022 Major in Ecology & Biodiversity (Intensive) < PLO 4 > 2022 Major in Environmental Science < PLO 2 > 2021 Major in Ecology & Biodiversity (Intensive) < PLO 4 >
Offer in 2025 - 2026	Y        1st sem	Examination	Dec
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough mastery at an advanced level of extensive knowledge and skills required for attaining all the course learning outcomes. Show thorough grasp of the subject. Demonstrate strong analytical and critical abilities and logical thinking, with ability to apply knowledge to a wide range of complex, familiar and unfamiliar situations. Apply highly effective organizational and presentational skills. B Demonstrate substantial command of a broad range of knowledge and skills required for attaining at least most of the course learning outcomes. Show substantial grasp of the subject. Demonstrate evidence of analytical and critical abilities and logical thinking, and ability to apply knowledge to familiar and some unfamiliar situations. Apply effective organizational and presentational skills. C Demonstrate general but incomplete command of knowledge and skills required for attaining most of the course learning outcomes. Show general but incomplete grasp of the subject. Demonstrate evidence of some analytical and critical abilities and logical thinking, and ability to apply knowledge to most familiar situations. Apply moderately effective organizational and presentational skills. D Demonstrate partial but limited command of knowledge and skills required for attaining some of the course learning outcomes. Show partial but limited grasp, with retention of some relevant information, of the subject. Demonstrate evidence of some coherent and logical thinking, but with limited analytical and critical abilities. Show limited ability to apply knowledge to solve problems. Apply limited or barely effective organizational and presentational skills. Fail Demonstrate little or no evidence of command of knowledge and skills required for attaining the course learning outcomes. Show evidence of little or no grasp of the knowledge and understanding of the subject. Lack of analytical and critical abilities, logical and coherent thinking. Show very little or no ability to apply knowledge to solve problems. Organization and presentational skills are minimally effective or ineffective.
Communication-intensive Course	N
Course Type	Lecture-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Lectures 36.0 Tutorials 12.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments 30.0 1,2,3,4,5 Examination 50.0 1,2,3,4,5 Test 20.0 1,2,3,4,5
Required/recommended reading and online materials	(Textbook for the course) Petrucci; Herring; Madura; Bissonnette: General Chemistry - Principles and Modern Applications, latest edition, Pearson. (Other reference books) Brown; LeMay; Bursten; Murphy; Woodward; Stoltzfus: Chemistry - The Central Science, latest edition, Pearson. Tro: Chemistry - A Molecular Approach, latest edition, Pearson. Robinson; McMurry; Fay: Chemistry, latest edition, Pearson.
Course Website	NIL
Additional Course Information	Suggested follow-up course: CHEM1042 General Chemistry I

CHEM1042 General chemistry I (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	450
Course Co-ordinator	Dr A T L Li, Chemistry < litla@hku.hk >
Teachers Involved	(Dr A T L Li,Chemistry)
Course Objectives	The course aims to provide students with a solid foundation of the basic principles and concepts of chemistry. It also provides students with hands-on training of basic laboratory skills and techniques including volumetric analysis, preparation, purification and characterization of chemical substances and some basic instrumental methods. Students will be equipped with a good foundation of theoretical and practical knowledge and skills for further studies in Chemistry.
Course Contents & Topics	1. Atoms: the quantum world Electromagnetic radiation and matter; Planck's quantum theory; the Bohr model of the hydrogen atom; the quantum mechanical model of the atom; quantum numbers, energy levels, and atomic orbitals; shapes of atomic orbitals; electron configurations; periodic trends. 2. Chemical bonding and structures Review on covalent, ionic and metallic bond. Molecular structures (VSEPR, VB theory) and intermolecular forces. 3. Thermodynamics Heat, work, internal energy and enthalpy; the First Law of thermodynamics; Hess's Law; introduction to entropy and spontaneity of changes. 4. Chemical kinetics Reaction rate; factors that influence reaction rate; rate laws: differential and integrated rate laws; effects of temperature and catalysts in reaction rate; energy profile and reaction mechanisms. 5. Acid-base equilibria Acid-base concepts; strength of acids/bases; equilibria in solutions of weak acids/bases; ionisation constants; acid-base properties; molecular structure and acid-base behaviour; buffer solutions; acid-base indicators; volumetric analysis involving acids and bases
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 demonstrate a basic knowledge and understanding of the microscopic nature of atomic structure and concepts of chemical bonding and their relationships with the bulk properties of matter CLO 2 demonstrate knowledge and understanding in relation to thermodynamics and kinetics of reactions as well as aqueous equilibria including acid-base equilibria CLO 3 apply the theories and concepts introduced in the course to solve problems, perform calculations, make predictions and rationalize trends CLO 4 carry out chemical experiments with proper procedures, record experimental oberservations accurately, and interpret and evaluate the experimental data CLO 5 organize and present chemical ideas in a clear, logical and coherent way CLO 6 demonstrate awareness and appreciation of the relevant applications of chemistry in society and in everyday life
Pre-requisites (and Co-requisites and Impermissible combinations)	Level 3 or above in HKDSE Chemistry or equivalent or a pass in CHEM1041. Not for students having taken any level 1 Chemistry course (except for CHEM1041) or above or any equivalent Chemistry course.
Course Status with Related Major/Minor /Professional Core	2025 Major in Biochemistry ( Core/Compulsory ) 2025 Major in Biological Sciences (Intensive) ( Core/Compulsory ) 2025 Major in Chemistry ( Core/Compulsory ) 2025 Major in Chemistry (Intensive) ( Core/Compulsory ) 2025 Major in Ecology & Biodiversity (Intensive) ( Disciplinary Elective ) 2025 Major in Environmental Science ( Disciplinary Elective ) 2025 Major in Molecular Biology & Biotechnology (Intensive) ( Core/Compulsory ) 2025 Minor in Chemistry ( Core/Compulsory ) 2025 Minor in Environmental Science ( Disciplinary Elective ) 2024 Major in Biochemistry ( Core/Compulsory ) 2024 Major in Biological Sciences (Intensive) ( Core/Compulsory ) 2024 Major in Chemistry ( Core/Compulsory ) 2024 Major in Chemistry (Intensive) ( Core/Compulsory ) 2024 Major in Ecology & Biodiversity (Intensive) ( Disciplinary Elective ) 2024 Major in Environmental Science ( Disciplinary Elective ) 2024 Major in Food & Nutritional Science ( Disciplinary Elective ) 2024 Major in Molecular Biology & Biotechnology (Intensive) ( Core/Compulsory ) 2024 Minor in Chemistry ( Core/Compulsory ) 2024 Minor in Environmental Science ( Disciplinary Elective ) 2023 Major in Biochemistry ( Core/Compulsory ) 2023 Major in Biological Sciences (Intensive) ( Core/Compulsory ) 2023 Major in Chemistry ( Core/Compulsory ) 2023 Major in Chemistry (Intensive) ( Core/Compulsory ) 2023 Major in Ecology & Biodiversity (Intensive) ( Disciplinary Elective ) 2023 Major in Environmental Science ( Disciplinary Elective ) 2023 Major in Food & Nutritional Science ( Disciplinary Elective ) 2023 Major in Molecular Biology & Biotechnology (Intensive) ( Core/Compulsory ) 2023 Minor in Chemistry ( Core/Compulsory ) 2023 Minor in Environmental Science ( Disciplinary Elective ) 2022 Major in Biochemistry ( Core/Compulsory ) 2022 Major in Biological Sciences (Intensive) ( Core/Compulsory ) 2022 Major in Chemistry ( Core/Compulsory ) 2022 Major in Chemistry (Intensive) ( Core/Compulsory ) 2022 Major in Ecology & Biodiversity (Intensive) ( Disciplinary Elective ) 2022 Major in Environmental Science ( Disciplinary Elective ) 2022 Major in Food & Nutritional Science ( Disciplinary Elective ) 2022 Major in Molecular Biology & Biotechnology (Intensive) ( Core/Compulsory ) 2022 Minor in Chemistry ( Core/Compulsory ) 2022 Minor in Environmental Science ( Disciplinary Elective ) 2021 Major in Biochemistry ( Core/Compulsory ) 2021 Major in Biological Sciences (Intensive) ( Core/Compulsory ) 2021 Major in Chemistry ( Core/Compulsory ) 2021 Major in Chemistry (Intensive) ( Core/Compulsory ) 2021 Major in Ecology & Biodiversity (Intensive) ( Disciplinary Elective ) 2021 Major in Environmental Science ( Core/Compulsory ) 2021 Major in Food & Nutritional Science ( Disciplinary Elective ) 2021 Major in Molecular Biology & Biotechnology (Intensive) ( Core/Compulsory ) 2021 Minor in Chemistry ( Core/Compulsory ) 2021 Minor in Environmental Science ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Biochemistry < PLO 1,2,3,4,5 > 2025 Major in Biological Sciences (Intensive) < PLO 1,2 > 2025 Major in Chemistry < PLO 1,2,4,5 > 2025 Major in Chemistry (Intensive) < PLO 1,2,4,5 > 2025 Major in Ecology & Biodiversity (Intensive) < PLO 4 > 2025 Major in Environmental Science < PLO 1,2 > 2025 Major in Molecular Biology & Biotechnology (Intensive) < PLO 1,2,3,4 > 2024 Major in Biochemistry < PLO 1,2,3,4,5 > 2024 Major in Biological Sciences (Intensive) < PLO 1,2 > 2024 Major in Chemistry < PLO 1,2,4,5 > 2024 Major in Chemistry (Intensive) < PLO 1,2,4,5 > 2024 Major in Ecology & Biodiversity (Intensive) < PLO 4 > 2024 Major in Environmental Science < PLO 1,2 > 2024 Major in Food & Nutritional Science < PLO 1,2,3 > 2024 Major in Molecular Biology & Biotechnology (Intensive) < PLO 1,2,3,4 > 2023 Major in Biochemistry < PLO 1,2,3,4,5 > 2023 Major in Biological Sciences (Intensive) < PLO 1,2 > 2023 Major in Chemistry < PLO 1,2,4,5 > 2023 Major in Chemistry (Intensive) < PLO 1,2,4,5 > 2023 Major in Ecology & Biodiversity (Intensive) < PLO 4 > 2023 Major in Environmental Science < PLO 1,2 > 2023 Major in Food & Nutritional Science < PLO 1,2,3 > 2023 Major in Molecular Biology & Biotechnology (Intensive) < PLO 1,2,3,4 > 2022 Major in Biochemistry < PLO 1,2,3,4,5 > 2022 Major in Biological Sciences (Intensive) < PLO 1,2 > 2022 Major in Chemistry < PLO 1,2,4,5 > 2022 Major in Chemistry (Intensive) < PLO 1,2,4,5 > 2022 Major in Ecology & Biodiversity (Intensive) < PLO 4 > 2022 Major in Environmental Science < PLO 1,2 > 2022 Major in Food & Nutritional Science < PLO 1,2,3 > 2022 Major in Molecular Biology & Biotechnology (Intensive) < PLO 1,2,3,4 > 2021 Major in Biochemistry < PLO 1,2,3,4,5 > 2021 Major in Biological Sciences (Intensive) < PLO 1,2 > 2021 Major in Chemistry < PLO 1,2,4,5 > 2021 Major in Chemistry (Intensive) < PLO 1,2,4,5 > 2021 Major in Ecology & Biodiversity (Intensive) < PLO 4 > 2021 Major in Environmental Science < PLO 1,2 > 2021 Major in Food & Nutritional Science < PLO 1,2,3 > 2021 Major in Molecular Biology & Biotechnology (Intensive) < PLO 1,2,3,4 >
Offer in 2025 - 2026	Y        1st sem    2nd sem	Examination	Dec    May
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough mastery at an advanced level of extensive knowledge and skills required for attaining all the course learning outcomes. Show thorough grasp of the subject. Demonstrate strong analytical and critical abilities and logical thinking, with ability to apply knowledge to a wide range of complex, familiar and unfamiliar situations. Show highly effective lab skills and techniques. Apply highly effective organizational and presentational skills. B Demonstrate substantial command of a broad range of knowledge and skills required for attaining at least most of the course learning outcomes. Show substantial grasp of the subject. Demonstrate evidence of analytical and critical abilities and logical thinking, and ability to apply knowledge to familiar and some unfamiliar situations. Show effective lab skills and techniques. Apply effective organizational and presentational skills. C Demonstrate general but incomplete command of knowledge and skills required for attaining most of the course learning outcomes. Show general but incomplete grasp of the subject. Demonstrate evidence of some analytical and critical abilities and logical thinking, and ability to apply knowledge to most familiar situations. Show moderately effective lab skills and techniques. Apply moderately effective organizational and presentational skills. D Demonstrate partial but limited command of knowledge and skills required for attaining some of the course learning outcomes. Show partial but limited grasp, with retention of some relevant information, of the subject. Demonstrate evidence of some coherent and logical thinking, but with limited analytical and critical abilities. Show limited ability to apply knowledge to solve problems. Demonstrate partially effective lab skills and techniques. Apply limited or barely effective organizational and presentational skills. Fail Demonstrate little or no evidence of command of knowledge and skills required for attaining the course learning outcomes. Show evidence of little or no grasp of the knowledge and understanding of the subject. Lack of analytical and critical abilities, logical and coherent thinking. Show very little or no ability to apply knowledge to solve problems. Demonstrate minimally effective or ineffective lab skills and techniques. Organization and presentational skills are minimally effective or ineffective.
Communication-intensive Course	N
Course Type	Lecture with laboratory component course
Course Teaching & Learning Activities	Activities Details No. of Hours Laboratory 24.0 Lectures 24.0 Tutorials 6.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Examination 50.0 1,2,3,5,6 Laboratory reports including lab-class performance & pre-lab assignments 30.0 1,2,3,4,5,6 Test (or Assignment) 20.0 1,2,3,5,6
Required/recommended reading and online materials	(Textbook for the course) Petrucci; Herring; Madura; Bissonnette: General Chemistry - Principles and Modern Applications, latest edition, Pearson. (Other reference books) Brown; LeMay; Bursten; Murphy; Woodward; Stoltzfus: Chemistry - The Central Science, latest edition, Pearson. Tro: Chemistry - A Molecular Approach, latest edition, Pearson. Robinson; McMurry; Fay: Chemistry, latest edition, Pearson.
Course Website	NIL
Additional Course Information	Laboratory classes are mandatory.  Students must attend ALL lab classes, complete ALL experiments and laboratory reports to pass this course.

CHEM1043 General chemistry II (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	280
Course Co-ordinator	Dr A T L Li, Chemistry < litla@hku.hk >
Teachers Involved	(Dr A T L Li,Chemistry) (Prof D L Phillips,Chemistry) (Prof S K Lee,Chemistry)
Course Objectives	This course is a continuation of CHEM1042 General Chemistry I.  It aims to further consolidate some of the important fundamentals of chemistry that underlie many topics and principles across the physical sciences.  The course prepares students to pursue a major in chemistry or in other aspects that require a good foundation in chemistry.
Course Contents & Topics	1. Gases Simple gas laws; ideal gas equation; gases in chemical reactions; mixture of gases; kinetic-molecular theory of gases; diffusion and effusion; non-ideal gases. 2. Structure and Bonding: The Delocalized Approach: Molecular Orbital Theory Bonding in homonuclear and heteronuclear diatomic molecules of first and second period of elements; bonding in some simple polyatomic molecules; bonding in metals (band theory). 3. Solutions and their Properties Types of solutions; intermolecular forces and the solution process; solution formation and equilibrium; solubilities of gases; vapor pressures of solutions; osmotic pressure; freezing-point  depression and boiling-point elevation of nonelectrolyte solutions; solutions of electrolytes; colloidal mixtures. 4. Solubility and Complex-Ion Equilibria Solubility product constant; relationship between solubility and Ksp; common-ion effect in solubility equilibria; limitations of the Ksp concept; precipitation; solubility and pH; equilibria involving complex ions; qualitative cation analysis. 5. Spontaneous Change Entropy change; second law and third law of thermodynamics; Gibbs free energy change of a system; Gibbs free energy of reactions; coupled reactions 6. Electrochemistry Electrode potentials and their measurement; standard electrode potentials; Ecell, delta G, and K; Ecell as a functions of concentrations; batteries; corrosion; electrolysis; industrial electrolysis processes.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 demonstrate a knowledge and understanding of the properties and behavior of gases and apply gas laws and kinetic-molecular theory to processes involving gases CLO 2 demonstrate a knowledge and understanding in relation to solutions and their properties, solubility and complex-ion equilibria, and also electrochemistry CLO 3 apply molecular orbital theory to explain the formation and properties of diatomic molecules of first and second period of elements and of some simple polyatomic molecules CLO 4 demonstrate a knowledge and understanding of the relationship between free energy and spontaneity of reaction CLO 5 apply the theories and concepts introduced in the course to solve problems, perform calculations, make predictions and rationalize trends CLO 6 organize and present chemical ideas in a clear, logical and coherent way CLO 7 demonstrate awareness of the relevant applications of chemistry in society and in everyday life
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM1042
Course Status with Related Major/Minor /Professional Core	2025 Major in Biochemistry ( Core/Compulsory ) 2025 Major in Biological Sciences (Intensive) ( Core/Compulsory ) 2025 Major in Chemistry ( Core/Compulsory ) 2025 Major in Chemistry (Intensive) ( Core/Compulsory ) 2025 Major in Molecular Biology & Biotechnology (Intensive) ( Core/Compulsory ) 2025 Minor in Chemistry ( Core/Compulsory ) 2024 Major in Biochemistry ( Core/Compulsory ) 2024 Major in Biological Sciences (Intensive) ( Core/Compulsory ) 2024 Major in Chemistry ( Core/Compulsory ) 2024 Major in Chemistry (Intensive) ( Core/Compulsory ) 2024 Major in Molecular Biology & Biotechnology (Intensive) ( Core/Compulsory ) 2024 Minor in Chemistry ( Core/Compulsory ) 2023 Major in Biochemistry ( Core/Compulsory ) 2023 Major in Biological Sciences (Intensive) ( Core/Compulsory ) 2023 Major in Chemistry ( Core/Compulsory ) 2023 Major in Chemistry (Intensive) ( Core/Compulsory ) 2023 Major in Molecular Biology & Biotechnology (Intensive) ( Core/Compulsory ) 2023 Minor in Chemistry ( Core/Compulsory ) 2022 Major in Biochemistry ( Core/Compulsory ) 2022 Major in Biological Sciences (Intensive) ( Core/Compulsory ) 2022 Major in Chemistry ( Core/Compulsory ) 2022 Major in Chemistry (Intensive) ( Core/Compulsory ) 2022 Major in Molecular Biology & Biotechnology (Intensive) ( Core/Compulsory ) 2022 Minor in Chemistry ( Core/Compulsory ) 2021 Major in Biochemistry ( Core/Compulsory ) 2021 Major in Biological Sciences (Intensive) ( Core/Compulsory ) 2021 Major in Chemistry ( Core/Compulsory ) 2021 Major in Chemistry (Intensive) ( Core/Compulsory ) 2021 Major in Molecular Biology & Biotechnology (Intensive) ( Core/Compulsory ) 2021 Minor in Chemistry ( Core/Compulsory )
Course to PLO Mapping	2025 Major in Biochemistry < PLO 1,2,3,4,5 > 2025 Major in Biological Sciences (Intensive) < PLO 1,2 > 2025 Major in Chemistry < PLO 1,2,4,5 > 2025 Major in Chemistry (Intensive) < PLO 1,2,4,5 > 2025 Major in Molecular Biology & Biotechnology (Intensive) < PLO 1,3,4,5 > 2024 Major in Biochemistry < PLO 1,2,3,4,5 > 2024 Major in Biological Sciences (Intensive) < PLO 1,2 > 2024 Major in Chemistry < PLO 1,2,4,5 > 2024 Major in Chemistry (Intensive) < PLO 1,2,4,5 > 2024 Major in Molecular Biology & Biotechnology (Intensive) < PLO 1,3,4,5 > 2023 Major in Biochemistry < PLO 1,2,3,4,5 > 2023 Major in Biological Sciences (Intensive) < PLO 1,2 > 2023 Major in Chemistry < PLO 1,2,4,5 > 2023 Major in Chemistry (Intensive) < PLO 1,2,4,5 > 2023 Major in Molecular Biology & Biotechnology (Intensive) < PLO 1,3,4,5 > 2022 Major in Biochemistry < PLO 1,2,3,4,5 > 2022 Major in Biological Sciences (Intensive) < PLO 1,2 > 2022 Major in Chemistry < PLO 1,2,4,5 > 2022 Major in Chemistry (Intensive) < PLO 1,2,4,5 > 2022 Major in Molecular Biology & Biotechnology (Intensive) < PLO 1,3,4,5 > 2021 Major in Biochemistry < PLO 1,2,3,4,5 > 2021 Major in Biological Sciences (Intensive) < PLO 1,2 > 2021 Major in Chemistry < PLO 1,2,4,5 > 2021 Major in Chemistry (Intensive) < PLO 1,2,4,5 > 2021 Major in Molecular Biology & Biotechnology (Intensive) < PLO 1,3,4,5 >
Offer in 2025 - 2026	Y        1st sem    2nd sem	Examination	Dec    May
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough mastery at an advanced level of extensive knowledge and skills required for attaining all the course learning outcomes. Show thorough grasp of the subject. Demonstrate strong analytical and critical abilities and logical thinking, with ability to apply knowledge to a wide range of complex, familiar and unfamiliar situations. Apply highly effective organizational and presentational skills. B Demonstrate substantial command of a broad range of knowledge and skills required for attaining at least most of the course learning outcomes. Show substantial grasp of the subject. Demonstrate evidence of analytical and critical abilities and logical thinking, and ability to apply knowledge to familiar and some unfamiliar situations. Apply effective organizational and presentational skills. C Demonstrate general but incomplete command of knowledge and skills required for attaining most of the course learning outcomes. Show general but incomplete grasp of the subject. Demonstrate evidence of some analytical and critical abilities and logical thinking, and ability to apply knowledge to most familiar situations. Apply moderately effective organizational and presentational skills. D Demonstrate partial but limited command of knowledge and skills required for attaining some of the course learning outcomes. Show partial but limited grasp, with retention of some relevant information, of the subject. Demonstrate evidence of some coherent and logical thinking, but with limited analytical and critical abilities. Show limited ability to apply knowledge to solve problems. Apply limited or barely effective organizational and presentational skills. Fail Demonstrate little or no evidence of command of knowledge and skills required for attaining the course learning outcomes. Show evidence of little or no grasp of the knowledge and understanding of the subject. Lack of analytical and critical abilities, logical and coherent thinking. Show very little or no ability to apply knowledge to solve problems. Organization and presentational skills are minimally effective or ineffective.
Communication-intensive Course	N
Course Type	Lecture-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Lectures 36.0 Tutorials 12.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments 30.0 1,2,3,4,5,6,7 Examination 50.0 1,2,3,4,5,6,7 Test 20.0 1,2,3,4,5,6,7
Required/recommended reading and online materials	(Textbook for the course) Petrucci; Herring; Madura; Bissonnette: General Chemistry - Principles and Modern Applications, latest edition, Pearson. (Other reference books) Brown; LeMay; Bursten; Murphy; Woodward; Stoltzfus: Chemistry - The Central Science, latest edition, Pearson. Tro: Chemistry - A Molecular Approach, latest edition, Pearson. Robinson; McMurry; Fay: Chemistry, latest edition, Pearson.
Course Website
Additional Course Information

CHEM1044 Mathematics in chemistry (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	80
Course Co-ordinator	Dr A M Y Yuen, Chemistry < maiyan@hku.hk >
Teachers Involved	(Dr A M Y Yuen,Chemistry)
Course Objectives	Mathematical calculations are necessary to explore important concepts in chemistry. This course aims to equip students with a basic knowledge of some of the mathematics that will be used in courses covered in the Chemistry-major curriculum to enable them to apply the mathematical skills to problems in chemistry. Students taking this course are expected to already have achieved level 2 or above in Module 1 or Module 2 of HKDSE Mathematics or equivalent, or a pass in MATH1011 University Mathematics I. As far as possible, the mathematical concepts covered in this course will be put in the context of chemical problems.
Course Contents & Topics	Applying mathematical tools, such as Algebra, Trigonometry, Calculus, Complex number, Vector, Matrix, Linear equation, Differential equation, in solving chemistry problems.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 demonstrate knowledge and understanding of the essential mathematics used in chemistry CLO 2 apply mathematical skills to solve basic problems in chemistry CLO 3 be more capable of coping with a higher level of mathematics required in relevant courses for chemistry major, in particular, in physical chemistry courses
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM1042 or already enrolled in this course; and Level 2 or above in Module 1 or Module 2 of HKDSE Mathematics or equivalent, or Pass in MATH1011 or SCNC1111
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2024 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2023 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2022 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2021 Major in Chemistry (Intensive) ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry (Intensive) < PLO 1,2,4,5 > 2024 Major in Chemistry (Intensive) < PLO 1,2,4,5 > 2023 Major in Chemistry (Intensive) < PLO 1,2,4,5 > 2022 Major in Chemistry (Intensive) < PLO 1,2,4,5 > 2021 Major in Chemistry (Intensive) < PLO 1,2,4,5 >
Offer in 2025 - 2026	Y        2nd sem	Examination	May
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate an excellent understanding of key concepts and ideas by being able to identify the appropriate theorems and their applications through correctly analysing problems, clearly and elegantly presenting correct logical reasoning and argumentation and being able to carry out computations carefully and correctly, and with some innovative approaches to solving problems. B Demonstrate a good understanding of key concepts and ideas by being able to identify the appropriate theorems and their applications through correctly analysing problems, but with some minor inadequacies in arguments, identifying the appropriate theorems or their applications and presentation or with some minor computational errors. C Demonstrate an acceptable understanding of key concepts and ideas by being able to correctly identify appropriate theorems, but with some inadequacies in applying the theorems through incorrectly analysing problems with poor argument and presentation or a number of minor computational errors. D Demonstrate some understanding of key concepts and ideas by being able to correctly identify appropriate theorems, but with substantial inadequacies in applying the theorems through incorrectly analysing problems with poor argument or presentation or with substantial computational errors. Fail Demonstrates poor and inadequate understanding by not being able to identify appropriate theorems or their applications, or not being able to complete the solution.
Communication-intensive Course	N
Course Type	Lecture-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Lectures 36.0 Tutorials 12.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments 20.0 1,2,3 Examination 50.0 1,2,3 Test mid-term test 30.0 1,2,3
Required/recommended reading and online materials	Graham Doggett, Martin Cockett: Maths for Chemists, 2nd Edition, RSC Erich Steiner: The Chemistry Maths Book, 2nd Edition, Oxford University Press
Course Website
Additional Course Information

   <<< This course is not offered in 2025-2026. Course details are subject to change. >>>

CHEM2041 Principles of chemistry (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	140
Course Co-ordinator	Dr I K Chu, Chemistry < ivankchu@hku.hk >
Teachers Involved
Course Objectives	This course is designed for non-chemistry major students covering basic principles of chemistry.
Course Contents & Topics	Gas Laws and the Kinetic Theory of Gases Thermodynamics: work, heat, the zeroth and first law of thermodynamics, internal energy, enthalpy, heat capacities, thermochemistry, Hess's Law, Kirchhoff's Law, the second and third laws of thermodynamics, entropy, Gibbs free energy, spontaneity, equilibrium, coupled reaction; Transport Phenomena: diffusion, viscosity of gases, diffusion in liquids and viscosity of liquids, ionic conduction; Chemical Kinetics: rate of reactions, orders of reactions, rate laws, reaction mechanism, experimental measurement of reaction rates, enzyme kinetics, enzyme inhibition, temperature effect on rates; Chemical Equilibrium; Equilibria in single-, and two component systems: phase transitions, phase diagrams and the phase rule, chemical potential; liquid/liquid systems; Introduction to acids and bases: calculation on concentration of different chemical species in a solution, diprotic and polyprotic acids, activity; Introduction to Spectroscopy: UV/Visible absorption spectroscopy, Beer-Lambert Law; IR Spectroscopy, identification of  functional groups; NMR Spectroscopy, Larmor frequency & chemical shift, peak integral, spin-spin coupling multiplicities; Mass Spectrometry,  isotopic distribution, determination of molecular formulae.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 explain the principles of the thermochemistry, chemical kinetics, chemical equilibrium, physical properties of solutions and gases CLO 2 explain the principles of the spectroscopy, and spectrometry
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM1042; and Not for students who have passed in CHEM2341, or have already enrolled in this course; and Not for students who have passed in CHEM2441, or have already enrolled in this course; and Not for students who have passed in CHEM2541, or have already enrolled in this course; and Not for Chemistry major students.
Course to PLO Mapping
Offer in 2025 - 2026	N	Examination
Offer in 2026 - 2027	N
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough knowledge and understanding of essential facts, concepts, principles and theories relating to the modern chemistry, instrumentations and applications of spectrometry and spectroscopy for chemical analysis. Show strong ability to apply and integrate knowledge and theory, and strong ability to analyze problems related to general chemistry and spectroscopy. B Demonstrate substantial command of knowledge and understanding of essential facts, concepts, principles and theories relating to the modern chemistry, instrumentations and applications of spectrometry and spectroscopy for chemical analysis. Show evidence to apply and integrate knowledge and theory, and ability to analyze problems related to general chemistry and spectroscopy. C Demonstrate general but incomplete command of knowledge and understanding of essential facts, concepts, principles and theories relating to the modern chemistry, instrumentations and applications of spectrometry and spectroscopy for chemical analysis. Show evidence of some abilities to apply and integrate knowledge and theory, and to analyze problems to most familiar situations to general chemistry and spectroscopy. D Demonstrate partial but limited command of knowledge and understanding of essential facts, concepts, principles and theories relating to the modern chemistry, instrumentations and applications of spectrometry and spectroscopy for chemical analysis. Show evidence of limited abilities to apply and integrate knowledge and theory, and limited ability to analyze problems to most familiar situations related to general chemistry and spectroscopy. Fail Demonstrate little or no evidence of command of knowledge and understanding of essential facts, concepts, principles and theories relating to the modern chemistry, instrumentations and applications of spectrometry and spectroscopy for chemical analysis. Show little or no evidence of abilities to apply and integrate knowledge and theory, and little or no ability to analyze problems to most familiar situations related to general chemistry and spectroscopy.
Communication-intensive Course	N
Course Type	Lecture-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Lectures 36.0 Tutorials 12.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments 25.0 1,2 Examination 75.0 1,2
Required/recommended reading and online materials	Spectroscopy for the biological science, by Gordon G. Hammes, Wiley-Interscience (2005)
Course Website	NIL
Additional Course Information	NIL

CHEM2241 Analytical chemistry I (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	120
Course Co-ordinator	Prof I K Chu (1st sem); Prof E C M Tse (2nd sem), Chemistry < ivankchu@hku.hk; ecmtse@hku.hk >
Teachers Involved	(Prof I K Chu,Chemistry) (Prof E C M Tse,Chemistry)
Course Objectives	The course aims to introduce the basic principles of chemical analysis. The principles of chemical measurement, including error analysis, quality assurance and calibration, data acquisition and processing, will be discussed with reference to methods of chemical analysis that are based on chemical equilibrium and stoichiometric reactions. The laboratory classes will include experiments demonstrating modern approaches of data acquisition and processing as well as chemical analysis based on chemical equilibrium.
Course Contents & Topics	Measurement: analog and digital measurement, accuracy and precision, comparing means and deviations, calibration curves and least square method for linear plots Quality assurance: validation of analytical procedures Chemical equilibrium and chemical analysis: aqueous solution and chemical equilibrium; analysis by acid-base reactivity, complexation reactivity, precipitation reactivity
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 explain the basic principles of chemical measurements CLO 2 explain the principles of classical methods of chemical analysis such as acid-base neutralization CLO 3 use laboratory apparatus for chemical analysis
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM1042; and Pass in CHEM1043, or already enrolled in this course
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry ( Core/Compulsory ) 2025 Major in Chemistry (Intensive) ( Core/Compulsory ) 2025 Major in Environmental Science ( Disciplinary Elective ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Core/Compulsory ) 2024 Major in Chemistry (Intensive) ( Core/Compulsory ) 2024 Major in Environmental Science ( Disciplinary Elective ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Core/Compulsory ) 2023 Major in Chemistry (Intensive) ( Core/Compulsory ) 2023 Major in Environmental Science ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Core/Compulsory ) 2022 Major in Chemistry (Intensive) ( Core/Compulsory ) 2022 Major in Environmental Science ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Core/Compulsory ) 2021 Major in Chemistry (Intensive) ( Core/Compulsory ) 2021 Major in Environmental Science ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry < PLO 2,3,4,5 > 2025 Major in Chemistry (Intensive) < PLO 2,3,4,5 > 2025 Major in Environmental Science < PLO 1,2,3 > 2024 Major in Chemistry < PLO 2,3,4,5 > 2024 Major in Chemistry (Intensive) < PLO 2,3,4,5 > 2024 Major in Environmental Science < PLO 1,2,3 > 2023 Major in Chemistry < PLO 2,3,4,5 > 2023 Major in Chemistry (Intensive) < PLO 2,3,4,5 > 2023 Major in Environmental Science < PLO 1,2,3 > 2022 Major in Chemistry < PLO 2,3,4,5 > 2022 Major in Chemistry (Intensive) < PLO 2,3,4,5 > 2022 Major in Environmental Science < PLO 1,2,3 > 2021 Major in Chemistry < PLO 2,3,4,5 > 2021 Major in Chemistry (Intensive) < PLO 2,3,4,5 > 2021 Major in Environmental Science < PLO 1,2,3 >
Offer in 2025 - 2026	Y        1st sem    2nd sem	Examination	Dec    May
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough grasp of the subject. Show evidence of strong analytical abilities, logical and independent thinking, and ablility to apply knowledge to a wide range of complex, familiar and unfamiliar situations. Demonstrate highly proficient lab skills and techniques and critical use of data and results to draw appropriate and insightful conclusions. Demonstrate highly effective organization and presentation skills. B Demonstrate substantial grasp of the subject. Show evidence of analytical abilities and logical thinking, some evidence of independent thinking, and ability to apply knowledge to familiar and some unfamiliar situations. Demonstrate proficient lab skills and techniques and correct use of data and results to draw appropriate conclusions. Demonstrate effective organization and presentation skills. C Demonstrate general but incomplete grasp of the subject. Show evidence of some analytical abilities and logical thinking, little evidence of independent thinking, and ability to apply knowledge to most familiar situations. Demonstrate adequate lab skills and techniques and mostly correct but some erroneous use of data and results to draw appropriate conclusions. Demonstrate moderately effective organization and presentation skills. D Demonstrate partial but limited grasp, with retention of some relevant information, of the subject. Show evidence of limited analytical abilities, little or no evidence of independent thinking, and limited ability to apply knowledge to solve problems. Demonstrate partially effective lab skills and techniques and limited ability to use data and results to draw appropriate conclusions. Demonstrate limited or barely effective organization and presentation skills. Fail Demonstrate little or no grasp of the knowledge and understanding of the subject. Show little or no evidence of analytical abilities, logical and independent thinking, and very little or no ability to apply knowledge to solve problems. Demonstrate minimally effective or ineffective lab skills and techniques and misuse of data and results and/or unable to draw appropriate conclusions. Demonstrate incoherent organization and poor presentation skills.
Communication-intensive Course	N
Course Type	Lecture with laboratory component course
Course Teaching & Learning Activities	Activities Details No. of Hours Laboratory 24.0 Lectures 24.0 Tutorials 6.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments 10.0 1,2 Examination 50.0 1,2 Laboratory reports 20.0 3 Test 20.0 1,2
Required/recommended reading and online materials	Skoog, West, Holler and Crouch, "Fundamentals of Analytical Chemistry", latest edition, Cengage Learning
Course Website	NIL
Additional Course Information	Laboratory classes are mandatory.  Students must complete ALL experiments and laboratory reports to pass this course.

CHEM2341 Inorganic chemistry I (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	120
Course Co-ordinator	Prof H Y Au Yeung, Chemistry < hoyuay@hku.hk >
Teachers Involved	(Dr A M Y Yuen,Chemistry) (Prof H Y Au Yeung,Chemistry)
Course Objectives	To provide students with the basic principles and knowledge of inorganic chemistry and to introduce their relevance to biological processes and materials science. This course provides the foundation for further studies in inorganic chemistry.
Course Contents & Topics	Acid-base concept; structure and bonding of transition metal complexes and main group compounds; electronic absorption and magnetic properties of metal complexes; chemical reactions of metal complexes: redox and substitution; chemistry of selected main group elements and transition metal complexes and their relevance to biology and materials.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 understand the basic principles and concepts of inorganic chemistry and appreciate their relevance to selected examples of biological processes and materials science CLO 2 demonstrate knowledge and understanding of the acid-base concept and definition CLO 3 demonstrate knowledge and understanding of the structure and bonding of main group compounds and transition metal complexes and their relevance to the electronic absorption and magnetic properties of transition metal complexes CLO 4 demonstrate knowledge and understanding of the thermodynamic stability of metal complex formation and the thermodynamic and kinetic aspects of substitution and redox reactions CLO 5 demonstrate knowledge and understanding of the role of main group elements and transition metal complexes in bioinorganic chemistry
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM1042; and Pass in CHEM1043, or already enrolled in this course
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry ( Core/Compulsory ) 2025 Major in Chemistry (Intensive) ( Core/Compulsory ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Core/Compulsory ) 2024 Major in Chemistry (Intensive) ( Core/Compulsory ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Core/Compulsory ) 2023 Major in Chemistry (Intensive) ( Core/Compulsory ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Core/Compulsory ) 2022 Major in Chemistry (Intensive) ( Core/Compulsory ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Core/Compulsory ) 2021 Major in Chemistry (Intensive) ( Core/Compulsory ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry < PLO 2,3,4 > 2025 Major in Chemistry (Intensive) < PLO 2,3,4 > 2024 Major in Chemistry < PLO 2,3,4 > 2024 Major in Chemistry (Intensive) < PLO 2,3,4 > 2023 Major in Chemistry < PLO 2,3,4 > 2023 Major in Chemistry (Intensive) < PLO 2,3,4 > 2022 Major in Chemistry < PLO 2,3,4 > 2022 Major in Chemistry (Intensive) < PLO 2,3,4 > 2021 Major in Chemistry < PLO 2,3,4 > 2021 Major in Chemistry (Intensive) < PLO 2,3,4 >
Offer in 2025 - 2026	Y        1st sem    2nd sem	Examination	Dec    May
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough knowledge and understanding of essential facts, concepts, principles, and theories relating to the basic foundation knowledge of inorganic chemistry, especially those related to acid-base concept; structure and bonding of main group compounds and metal complexes; electronic absorption spectroscopy, magnetic properties as well as thermodynamic and kinetic aspects of metal complexes and their reactions; and their relevance to biological processes and materials science. Show strong ability to apply and integrate knowledge and theory relating to the basic foundation knowledge of inorganic chemistry. Show strong ability to analyze novel problems and critical use of data and experimental results to draw appropriate and insightful conclusions relating to the basic principles and knowledge of inorganic chemistry. Demonstrate highly effective basic laboratory skills and techniques, especially in the synthesis and characterization of inorganic compounds and metal complexes. B Demonstrate substantial command of knowledge and understanding of essential facts, concepts, principles, and theories relating to the basic foundation knowledge of inorganic chemistry, especially those related to acid-base concept; structure and bonding of main group compounds and metal complexes; electronic absorption spectroscopy, magnetic properties as well as thermodynamic and kinetic aspects of metal complexes and their reactions; and their relevance to biological processes and materials science. Show evidence to apply and integrate knowledge and theory relating to the basic foundation knowledge of inorganic chemistry. Show evidence to analyze novel problems and correct use of data and experimental results to draw appropriate conclusions relating to the basic principles and knowledge of inorganic chemistry. Demonstrate effective basic laboratory skills and techniques, especially in the synthesis and characterization of inorganic compounds and metal complexes. C Demonstrate general but incomplete command of knowledge and understanding of essential facts, concepts, principles, and theories relating to the basic foundation knowledge of inorganic chemistry, especially those related to acid-base concept; structure and bonding of main group compounds and metal complexes; electronic absorption spectroscopy, magnetic properties as well as thermodynamic and kinetic aspects of metal complexes and their reactions; and their relevance to biological processes and materials science. Show evidence of some abilities to apply and integrate knowledge and theory relating to the basic foundation knowledge of inorganic chemistry. Show ability to analyze problems to most familiar situations and mostly correct but erroneous use of data and experimental results to draw appropriate conclusions relating to the basic principles and knowledge of inorganic chemistry. Demonstrate moderately effective basic laboratory skills and techniques, especially in the synthesis and characterization of inorganic compounds and metal complexes. D Demonstrate partial but limited command of knowledge and understanding of essential facts, concepts, principles, and theories relating to the basic foundation knowledge of inorganic chemistry, especially those related to acid-base concept; structure and bonding of main group compounds and metal complexes; electronic absorption spectroscopy, magnetic properties as well as thermodynamic and kinetic aspects of metal complexes and their reactions; and their relevance to biological processes and materials science. Show evidence of limited abilities to apply and integrate knowledge and theory relating to the basic foundation knowledge of inorganic chemistry. Show limited ability to analyze problems to most familiar situations and mostly correct but erroneous use of data and experimental results to draw appropriate conclusions relating to the basic principles and knowledge of inorganic chemistry. Demonstrate partially effective basic laboratory skills and techniques, especially in the synthesis and characterization of inorganic compounds and metal complexes. Fail Demonstrate little or no evidence of command of knowledge and understanding of essential facts, concepts, principles, and theories relating to the basic foundation knowledge of inorganic chemistry, especially those related to acid-base concept; structure and bonding of main group compounds and metal complexes; electronic absorption spectroscopy, magnetic properties as well as thermodynamic and kinetic aspects of metal complexes and their reactions; and their relevance to biological processes and materials science. Show little or no evidence of abilities to apply and integrate knowledge and theory relating to the basic foundation knowledge of inorganic chemistry. Show little or no ability to analyze problems to most familiar situations and erroneous use of data and experimental results to draw appropriate conclusions relating to the basic principles and knowledge of inorganic chemistry. Demonstrate minimally effective basic laboratory skills and techniques, especially in the synthesis and characterization of inorganic compounds and metal complexes.
Communication-intensive Course	N
Course Type	Lecture with laboratory component course
Course Teaching & Learning Activities	Activities Details No. of Hours Laboratory 24.0 Lectures 24.0 Tutorials 6.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments 15.0 1,2,3,4,5 Examination 50.0 1,2,3,4,5 Laboratory reports 15.0 1,2,3,4,5 Test 20.0 1,2,3,4,5
Required/recommended reading and online materials	F. A. Cotton ; G. Wilkinson ; P. L. Gaus : Basic Inorganic Chemistry (John Wiley & Sons, 1995, 3rd ed.) P. Atkins, T. Overton, J. Rourke, M. Weller and F. Armstrong: Shriver & Atkins Inorganic Chemistry (Oxford University Press, 2006, 4th ed.)
Course Website	NIL
Additional Course Information	Laboratory classes are mandatory.  Students must complete ALL experiments and laboratory reports to pass this course.

CHEM2441 Organic chemistry I (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	200
Course Co-ordinator	Prof S K Lee (1st sem); Prof XY Chen (2nd sem), Chemistry < skchem@hku.hk; aspen@hku.hk >
Teachers Involved	(Prof A M Li,Chemistry) (Prof S K Lee,Chemistry) (Prof X Y Chen,Chemistry)
Course Objectives	To provide students with the basic principles to understand the structure and reactivity of organic molecules, with examples illustrating the role of organic chemistry in daily life and industry. This course serves as the first part of the complete program on fundamental organic chemistry, to be followed up by CHEM3441 Organic Chemistry II.
Course Contents & Topics	Structure and bonding of organic compounds, three dimensional structures of organic molecules, conformational stereochemistry, chirality.  Chemistry of alkanes, cycloalkanes, alkenes, alkynes, haloalkanes, dienes, alcohols, thiols, and ethers.  Organometallic chemistry for organic synthesis.  Principles of organic synthesis.  Detailed considerations of reaction mechanisms.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 visualize and draw stereochemically correct representations of three-dimensional organic molecules CLO 2 define, classify, and name chirality, stereoisomers and diastereomers CLO 3 understand the basic mechanism types: electrophilic addition, SN1, SN2, E1, E2, and radical propagation mechanisms CLO 4 apply the basic mechanisms to rationalize the conditions and derive the outcomes of the reactions of alkanes, alkyl halides, alkenes, dienes, alkynes, alcohols, ethers, epoxides, and organometallic compounds CLO 5 understand the structure, and bonding of alkanes, alkenes, alkynes and dienes CLO 6 apply reactions to the synthesis of target alkane, alkyl halide, alkene, diene, alkyne, alcohol, ether, epoxides, and bifunctional molecules CLO 7 appreciate the relevance of organic chemistry in biological processes and daily life
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM1042; and Pass in CHEM1043, or already enrolled in this course
Course Status with Related Major/Minor /Professional Core	2025 Major in Biochemistry ( Core/Compulsory ) 2025 Major in Chemistry ( Core/Compulsory ) 2025 Major in Chemistry (Intensive) ( Core/Compulsory ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Biochemistry ( Core/Compulsory ) 2024 Major in Chemistry ( Core/Compulsory ) 2024 Major in Chemistry (Intensive) ( Core/Compulsory ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Biochemistry ( Core/Compulsory ) 2023 Major in Chemistry ( Core/Compulsory ) 2023 Major in Chemistry (Intensive) ( Core/Compulsory ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Biochemistry ( Core/Compulsory ) 2022 Major in Chemistry ( Core/Compulsory ) 2022 Major in Chemistry (Intensive) ( Core/Compulsory ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Biochemistry ( Core/Compulsory ) 2021 Major in Chemistry ( Core/Compulsory ) 2021 Major in Chemistry (Intensive) ( Core/Compulsory ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Biochemistry < PLO 1,2,3,4,5 > 2025 Major in Chemistry < PLO 1,2,3 > 2025 Major in Chemistry (Intensive) < PLO 1,2,3 > 2024 Major in Biochemistry < PLO 1,2,3,4,5 > 2024 Major in Chemistry < PLO 1,2,3 > 2024 Major in Chemistry (Intensive) < PLO 1,2,3 > 2023 Major in Biochemistry < PLO 1,2,3,4,5 > 2023 Major in Chemistry < PLO 1,2,3 > 2023 Major in Chemistry (Intensive) < PLO 1,2,3 > 2022 Major in Biochemistry < PLO 1,2,3,4,5 > 2022 Major in Chemistry < PLO 1,2,3 > 2022 Major in Chemistry (Intensive) < PLO 1,2,3 > 2021 Major in Biochemistry < PLO 1,2,3,4,5 > 2021 Major in Chemistry < PLO 1,2,3 > 2021 Major in Chemistry (Intensive) < PLO 1,2,3 >
Offer in 2025 - 2026	Y        1st sem    2nd sem	Examination	Dec    May
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate a thorough mastery at an advanced level of knowledge and understanding of facts and concepts pertaining to the chemical properties, reactions and mechanisms of organic chemistry. Show a strong ability to integrate knowledge and theory, and a strong ability to analyze and solve novel organic chemistry problems. Demonstrate highly effective organization, understanding, and execution of lab skills and techniques in organic chemistry experiments. B Demonstrate substantial command of knowledge and understanding of essential facts and concepts pertaining to the chemical properties, reactions and mechanisms of organic chemistry. Show evidence of ability to integrate knowledge and theory, and evidence of ability to analyze and solve novel organic chemistry problems. Demonstrate effective organization, understanding, and execution of lab skills and techniques in organic chemistry experiments. C Demonstrate a general but incomplete command of knowledge and understanding of essential facts and concepts pertaining to the chemical properties, reactions and mechanisms of organic chemistry. Show evidence of some ability to integrate knowledge and theory, and evidence of some ability to analyze novel problems. Show a mostly correct use of knowledge to solve most familiar problems. Demonstrate adequately effective organization, understanding, and execution of lab skills and techniques in organic chemistry experiments. D Demonstrate a partial but limited command of knowledge and understanding of essential facts and concepts pertaining to the chemical properties, reactions and mechanisms of organic chemistry. Show evidence of limited ability to integrate knowledge and theory, and a limited ability to analyze novel problems. Show some correct but also erroneous use of knowledge to solve most familiar problems. Demonstrate a partially effective organization, understanding and application of lab skills and techniques in organic chemistry experiments. Fail Demonstrate little or no evidence of command of knowledge and understanding of essential facts and concepts pertaining to the chemical properties, reactions and mechanisms of organic chemistry. Show little or no evidence of ability to apply and integrate knowledge and theory, and little or no ability to analyze novel problems. Show little or no evidence of ability to solve most familiar problems. Demonstrate minimal or no organization, understanding and application of lab skills and techniques in organic chemistry experiments.
Communication-intensive Course	N
Course Type	Lecture-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Lectures 24.0 Tutorials 36.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments (Assignments and participation) 30.0 1,2,3,4,5,6,7 Examination 50.0 1,2,3,4,5,6 Test 20.0 1,2,3,4,5,6
Required/recommended reading and online materials	Organic Chemistry, by Paula Y. Bruice, 8th Global Edition, Chapters 1-12.
Course Website	NIL
Additional Course Information	This course will be conducted as a blended learning course, in which the teaching material will be delivered using videos, along with face-to-face and online tutorials.

CHEM2442 Fundamentals of organic chemistry (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	100
Course Co-ordinator	Prof P H Toy, Chemistry < phtoy@hku.hk >
Teachers Involved	(Prof P H Toy,Chemistry)
Course Objectives	The major objective of this course is to give the students a basic understanding of organic chemistry, especially in the context of daily life.  This will be achieved through the introduction of the chemistry of organic functional groups that form the basis of organic molecules.  The concepts presented in the lectures will be reinforced by a series of laboratory experiments.
Course Contents & Topics	The chemistry of organic functional groups such as alkenes, alkynes, alkyl halides, alcohols, aldehydes, ketones, carboxylic acids and their derivatives, and amines will be discussed, as will the general concepts of molecular structure, conformation and stereochemistry.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 demonstrate basic understanding of the structure of organic molecules CLO 2 demonstrate basic understanding of the reactivity of organic molecules CLO 3 appreciate how organic chemistry plays an important role in everyday life
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM1042; and Not for students who have passed CHEM2441, or have already enrolled in this course.
Course Status with Related Major/Minor /Professional Core	2U000C00 Course not offered under any Major/Minor/Professional core 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Food & Nutritional Science ( Disciplinary Elective ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Food & Nutritional Science ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Food & Nutritional Science ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Food & Nutritional Science ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2024 Major in Food & Nutritional Science < PLO 1,2,3 > 2023 Major in Food & Nutritional Science < PLO 1,2,3 > 2022 Major in Food & Nutritional Science < PLO 1,2,3 > 2021 Major in Food & Nutritional Science < PLO 1,2,3 >
Offer in 2025 - 2026	Y        1st sem	Examination	Dec
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough mastery at an advanced level of extensive organic chemistry knowledge, and skills required for attaining all the course learning outcomes. Show strong analytical and critical abilities and logical thinking, with evidence of original thought, and ability to apply knowledge to a wide range of complex, familiar and unfamiliar problems. B Demonstrate substantial command of organic chemistry with a broad range of knowledge, and skills required for attaining at least most of the course learning outcomes. Show evidence of analytical and critical abilities and logical thinking, and ability to apply knowledge to familiar and some unfamiliar problems. C Demonstrate general but incomplete command of organic chemistry knowledge, and skills required for attaining most of the course learning outcomes. Show evidence of some analytical and critical abilities and logical thinking, and ability to apply knowledge to most familiar problems. D Demonstrate partial but limited command of organic chemistry knowledge, and skills required for attaining some of the course learning outcomes. Show evidence of some coherent and logical thinking, but with limited analytical and critical abilities. Show limited ability to apply knowledge to solve problems. Fail Demonstrate little or no evidence of command of organic chemistry knowledge, and skills required for attaining the course learning outcomes. Lack of analytical and critical abilities, logical and coherent thinking. Show very little or no ability to apply knowledge to solve problems.
Communication-intensive Course	N
Course Type	Lecture with laboratory component course
Course Teaching & Learning Activities	Activities Details No. of Hours Laboratory 20.0 Lectures 24.0 Tutorials 5.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Examination 50.0 1,2,3 Test (test/quiz) 50.0 1,2,3
Required/recommended reading and online materials	Bruice, P.Y.; Essential Organic Chemistry (Pearson, 2016, 3rd edition)
Course Website	NIL
Additional Course Information	Students who are planning to take CHEM3441 should take CHEM2441. Laboratory classes are mandatory.  Students must complete ALL experiments and take a written laboratory test in order to pass this course.

   <<< This course is not offered in 2025-2026. Course details are subject to change. >>>

CHEM2443 Fundamentals of organic chemistry for pharmacy students (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	60
Course Co-ordinator	Dr P H Toy, Chemistry < phtoy@hku.hk >
Teachers Involved	(Dr P H Toy,Chemistry)
Course Objectives	The major objective of this course is to give pharmacy students a basic understanding of organic chemistry, especially in the context of daily life.  This will be achieved through the introduction of the chemistry of organic functional groups that form the basis of organic molecules.  The concepts presented in the lectures will be reinforced by a series of laboratory experiments.
Course Contents & Topics	The chemistry of organic functional groups such as alkenes, alkynes, alkyl halides, alcohols, aldehydes, ketones, carboxylic acids and their derivatives, and amines will discussed, as will the general concepts of molecular structure, conformation and stereochemistry.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 demonstrate basic understanding of structure of organic molecules CLO 2 demonstrate basic understanding of the reactivity of organic molecules CLO 3 appreciate how organic chemistry plays an important role in everyday life
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM1042; and Not for students who have passed CHEM2442, or already enrolled in this course. (This course is for BPharm students only)
Course to PLO Mapping
Offer in 2025 - 2026	N	Examination
Offer in 2026 - 2027	N
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough mastery at an advanced level of extensive organic chemistry knowledge, and skills required for attaining all the course learning outcomes. Show strong analytical and critical abilities and logical thinking, with evidence of original thought, and ability to apply knowledge to a wide range of complex, familiar and unfamiliar problems. B Demonstrate substantial command of organic chemistry with a broad range of knowledge, and skills required for attaining at least most of the course learning outcomes. Show evidence of analytical and critical abilities and logical thinking, and ability to apply knowledge to familiar and some unfamiliar problems. C Demonstrate general but incomplete command of organic chemistry knowledge, and skills required for attaining most of the course learning outcomes. Show evidence of some analytical and critical abilities and logical thinking, and ability to apply knowledge to most familiar problems. D Demonstrate partial but limited command of organic chemistry knowledge, and skills required for attaining some of the course learning outcomes. Show evidence of some coherent and logical thinking, but with limited analytical and critical abilities. Show limited ability to apply knowledge to solve problems. Fail Demonstrate little or no evidence of command of organic chemistry knowledge, and skills required for attaining the course learning outcomes. Lack of analytical and critical abilities, logical and coherent thinking. Show very little or no ability to apply knowledge to solve problems.
Communication-intensive Course	N
Course Type	Lecture with laboratory component course
Course Teaching & Learning Activities	Activities Details No. of Hours Laboratory 20.0 Lectures 24.0 Tutorials 5.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Examination 60.0 1,2,3 Test Test/Quiz 40.0 1,2,3
Required/recommended reading and online materials	Bruice, P.Y.; Essential Organic Chemistry (Pearson, 2016, 3rd edition)
Course Website	NIL
Additional Course Information	Laboratory classes are mandatory.  Students must complete ALL experiments and laboratory reports to pass this course.

CHEM2541 Introductory physical chemistry (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	100
Course Co-ordinator	Prof J Y Tang, Chemistry < jinyao@hku.hk >
Teachers Involved	(Prof J Y Tang,Chemistry) (Prof R H Dong,Chemistry)
Course Objectives	The course aims to provide a rigorous understanding of equilibrium thermodynamics and chemical kinetics. Students are required to apply mathematical skills (derivations, integrations, and statistics) and fundamental physics to understand chemical reactions and related processes. Topics include the three laws of thermodynamics, thermodynamic properties of mixtures, solutions, chemical equilibrium, electrochemistry, rates of chemical reactions and reaction dynamics. Students will gain a good foundation of knowledge and skills for further study in advanced Physical Chemistry. Due to the involvement of math knowledge in this course, students are strongly encouraged to enroll in CHEM1044 Mathematics in chemistry, before enrolling in this course, if possible. An adequate maths background should benefit students in getting more learning this course.
Course Contents & Topics	The First Law of Thermodynamics Basic concepts of work, heat, energy, expansion work, heat transactions, enthalpy and adiabatic changes and examples in relation to biochemistry and materials science. The Second and Third Laws of Thermodynamics Direction of spontaneous change, entropy and the Third Law of Thermodynamics. Gibbs relationships and the development of thermodynamics to material science, information sciences. The application of three laws of thermodynamics for classical systems as well as new applications. Simple Mixtures The thermodynamics of phase equilibrium and surface. Thermodynamic description of mixtures, partial molar quantities, and chemical potentials of liquids. Activities of solvent, solute, regular solutions and ions in solution. The example in binary mixture will be discussed. Chemical Equilibrium Spontaneous chemical reactions, the Gibbs energy minimum and equilibrium. Response of equilibria to pressure, temperature. Electrochemistry Electrochemical cell, relationship of electrochemical potential to thermodynamic functions. Applications of electrochemistry in energy, material science, sensing. Rates of Chemical Reactions Empirical chemical kinetics including experimental methods, rates of reactions, integrated rate laws and temperature dependence of reactions and Reaction mechanism. The electrochemistry dynamics and basic knowledge in enzyme chemistry.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 demonstrate knowledge and understanding of the properties of gases, molecules in motion and the rates of chemical reactions CLO 2 understand and demonstrate knowledge of the three laws of thermodynamics CLO 3 understand and apply the concepts of chemical equilibrium and the response of chemical equilibria to temperature and pressure CLO 4 understand and demonstrate knowledge of electrochemistry and its relationship to thermodynamics, can build electrochemical cell and calculate thermodynamic functions from electrochemical reactions CLO 5 demonstrate knowledge and understanding of basic reaction dynamics including reaction mechanism and how mechanism determines reaction rate law
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM1042 and CHEM1043 Student are recommended (but not required) to take CHEM1044 before (or along with) taking this course.
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry ( Core/Compulsory ) 2025 Major in Chemistry (Intensive) ( Core/Compulsory ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Core/Compulsory ) 2024 Major in Chemistry (Intensive) ( Core/Compulsory ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Core/Compulsory ) 2023 Major in Chemistry (Intensive) ( Core/Compulsory ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Core/Compulsory ) 2022 Major in Chemistry (Intensive) ( Core/Compulsory ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Core/Compulsory ) 2021 Major in Chemistry (Intensive) ( Core/Compulsory ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry < PLO 1,2,3,5 > 2025 Major in Chemistry (Intensive) < PLO 1,2,3,5 > 2024 Major in Chemistry < PLO 1,2,3,5 > 2024 Major in Chemistry (Intensive) < PLO 1,2,3,5 > 2023 Major in Chemistry < PLO 1,2,3,5 > 2023 Major in Chemistry (Intensive) < PLO 1,2,3,5 > 2022 Major in Chemistry < PLO 1,2,3,5 > 2022 Major in Chemistry (Intensive) < PLO 1,2,3,5 > 2021 Major in Chemistry < PLO 1,2,3,5 > 2021 Major in Chemistry (Intensive) < PLO 1,2,3,5 >
Offer in 2025 - 2026	Y        2nd sem	Examination	May
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough mastery at an advanced level of extensive knowledge and skills required for attaining all the course learning outcomes. Show thorough grasp of the subject. Demonstrate strong analytical and critical abilities and logical thinking, with ability to apply knowledge to a wide range of complex, familiar and unfamiliar situations. B Demonstrate substantial command of a broad range of knowledge and skills required for attaining at least most of the course learning outcomes. Show substantial grasp of the subject. Demonstrate evidence of analytical and critical abilities and logical thinking, and ability to apply knowledge to familiar and some unfamiliar situations. C Demonstrate general but incomplete command of knowledge and skills required for attaining most of the course learning outcomes. Show general but incomplete grasp of the subject. Demonstrate evidence of some analytical and critical abilities and logical thinking, and ability to apply knowledge to most familiar situations. D Demonstrate partial but limited command of knowledge and skills required for attaining some of the course learning outcomes. Show partial but limited grasp, with retention of some relevant information, of the subject. Demonstrate evidence of some coherent and logical thinking, but with limited analytical and critical abilities. Show limited ability to apply knowledge to solve problems. Fail Demonstrate little or no evidence of command of knowledge and skills required for attaining the course learning outcomes. Show evidence of little or no grasp of the knowledge and understanding of the subject. Lack of analytical and critical abilities, logical and coherent thinking. Show very little or no ability to apply knowledge to solve problems.
Communication-intensive Course	N
Course Type	Lecture-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Lectures 36.0 Tutorials 12.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments (30% Assignments; 5% participation) 35.0 1,2,3,4,5 Examination 45.0 1,2,3,4,5 Test 20.0 1,2
Required/recommended reading and online materials	Required textbook: 'Physical Chemistry' by P. W. Atkins, latest edition Recommended Book: 'Physical Chemistry' 6th edition by Ira N. Levine
Course Website	NIL
Additional Course Information

CHEM3141 Environmental chemistry (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	50
Course Co-ordinator	Prof Y X Li, Chemistry < yxpli@hku.hk >
Teachers Involved	(Prof Y X Li,Chemistry)
Course Objectives	This course introduces students to Environmental Chemistry and enables them to understand the chemical principles involved in various environmental phenomena and processes.
Course Contents & Topics	Atmosphere chemistry: atmospheric composition and behavior, ozone, air pollution Energy and climate change: energy resources, carbon emission, and climate change Water chemistry: water resources, water pollution, water purification, and water crisis. Pollutants: persistent organic pollutants, pesticides, toxic heavy metals, toxicology Waste treatment:  landfill, incineration Big data analysis in environmental science
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 demonstrate knowledge on chemical principles of the various environmental phenomena and processes CLO 2 describe the practical processes of chemistry in atmosphere, water purification, waste treatment, and energy production CLO 3 critically discuss local and global environmental issues based on scientific principles and data CLO 4 apply knowledge to analyze chemical processes involved in various environmental problems
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM2241 or CHEM2341 or CHEM2441 or CHEM2442 or CHEM2541 For those who have not got the above pre-requisite but with a pass in CHEM1042 and a pass in ENVS2001, and will work hard to cope with the course, they are welcome to join the course.
Course Status with Related Major/Minor /Professional Core	2025 Major in Environmental Science ( Disciplinary Elective ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2025 Minor in Environmental Science ( Disciplinary Elective ) 2024 Major in Environmental Science ( Disciplinary Elective ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2024 Minor in Environmental Science ( Disciplinary Elective ) 2023 Major in Environmental Science ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2023 Minor in Environmental Science ( Disciplinary Elective ) 2022 Major in Environmental Science ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2022 Minor in Environmental Science ( Disciplinary Elective ) 2021 Major in Environmental Science ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective ) 2021 Minor in Environmental Science ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Environmental Science < PLO 1,2,3,4 > 2024 Major in Environmental Science < PLO 1,2,3,4 > 2023 Major in Environmental Science < PLO 1,2,3,4 > 2022 Major in Environmental Science < PLO 1,2,3,4 > 2021 Major in Environmental Science < PLO 1,2,3,4 >
Offer in 2025 - 2026	Y        2nd sem	Examination	May
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A - Demonstrate thorough grasp of the subject. - Demonstrate integration of the full range of appropriate theories, principles, and evidence. - Show evidence of strong analytical abilities, logical and independent thinking, and ablility to apply knowledge to a wide range of complex, familiar and unfamiliar situations. - Demonstrate highly effective organization and presentation skills. B - Demonstrate substantial grasp of the subject. - Demonstrate general integration of theories, principles, and evidence. - Show evidence of analytical abilities and logical thinking, some evidence of independent thinking, and ability to apply knowledge to familiar and some unfamiliar situations. - Demonstrate effective organization and presentation skills. C - Demonstrate general but incomplete grasp of the subject. - Demonstrate some partial integration of theories, principles, and evidence. - Show evidence of some analytical abilities and logical thinking, little evidence of independent thinking, and ability to apply knowledge to most familiar situations. - Demonstrate moderately effective organization and presentation skills. D - Demonstrate partial but limited grasp, with retention of some relevant information, of the subject. - Demonstrate limited integration of theories, principles, and evidence. - Show evidence of limited analytical abilities, little or no evidence of independent thinking, and limited ability to apply knowledge to solve problems. - Demonstrate limited or barely effective organization and presentation skills. Fail - Demonstrate little or no grasp of the knowledge and understanding of the subject. - Demonstrate little or inapt integration of theories, principles, and evidence. - Show little or no evidence of analytical abilities, logical and independent thinking, and very little or no ability to apply knowledge to solve problems. - Demonstrate incoherent organization and poor presentation skills.
Communication-intensive Course	N
Course Type	Lecture-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Lectures 36.0 Tutorials 3.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments 30% Assignment 1 (poster presentation); 20% Assignment 2 (two short quizzes) 50.0 1,2,3,4 Examination 50.0 1,2,3,4
Required/recommended reading and online materials	C. Baird and M. Cann: Environmental Chemistry, Freeman, latest edition. S.E. Manahan: Environmental Chemistry, Lewis Publishers, latest edition.
Course Website	NIL
Additional Course Information	NIL

   <<< This course is not offered in 2025-2026. Course details are subject to change. >>>

CHEM3142 Chemical process industries and analysis (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	60
Course Co-ordinator	Prof G K Y Chan, Chemistry < hrsccky@hku.hk >
Teachers Involved	(Prof G K Y Chan,Chemistry) (Visiting Professor,Chemistry)
Course Objectives	To familiarize with typical chemical industries important in local and global economy.  To understand the technology of chemicals manufacturing and chemical processes in general industry.
Course Contents & Topics	Process flow charts, units and conversions, materials and energy balances, unit operations.  Selection of chemical processes to include variation in products, scale, and types of operation, e.g. for petrochemical industries, industrial gases, beverage processes, chloroalkaline manufacturing.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 solve basic problems of energy and mass balances in chemical and environmental processes CLO 2 be familiarized with a few common chemical industries and chemical processes CLO 3 understand some general principles of industrial practice through plant visits
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM2241 or CHEM2341 or CHEM2441 or CHEM2442 or CHEM2541
Course Status with Related Major/Minor /Professional Core	2U000C00 Course not offered under any Major/Minor/Professional core 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping
Offer in 2025 - 2026	N	Examination
Offer in 2026 - 2027	N
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough knowledge of industrial chemical processes and mastery of mass and energy balance skills required for attaining all of the course learning outcomes. Show strong analytical and critical abilities and logical thinking, with evidence of original thought, and ability to apply knowledge to solve problems in a wide range of complex, familiar and unfamiliar situations. Critical use of data and sourcing of references. Apply highly effective organizational and presentational skills. B Demonstrate substantial knowledge of industrial chemical processes and command of mass and energy balance skills required for attaining at least most of the course learning outcomes. Show evidence of analytical and critical abilities and logical thinking, and ability to apply knowledge to solve problems in familiar and some unfamiliar situations. Correct use of data and sourcing of references. Apply effective organizational and presentational skills. C Demonstrate general but incomplete knowledge of industrial chemical processes and command of mass and energy balance skills required for attaining most of the course learning outcomes. Show evidence of some analytical and critical abilities and logical thinking, and ability to apply knowledge solve problems to most familiar situations. Mostly correct but some erroneous use of data and references. Apply moderately effective organizational and presentational skills. D Demonstrate partial but limited knowledge of industrial chemical processes and command of mass and energy balance skills required for attaining some of the course learning outcomes. Show evidence of some coherent and logical thinking, but with limited analytical and critical abilities. Show limited ability to apply knowledge to solve problems. Limited ability to use data and source references. Apply limited or barely effective organizational and presentational skills. Fail Demonstrate little or no evidence of knowledge of industrial chemical processes and command of mass and energy balance skills required for attaining the course learning outcomes. Lack of analytical and critical abilities, logical and coherent thinking. Show very little or no ability to apply knowledge to solve problems. Misuse of data and references. Organization and presentational skills are minimally effective or ineffective.
Communication-intensive Course	N
Course Type	Lecture with laboratory component course
Course Teaching & Learning Activities	Activities Details No. of Hours Field work 1 - 2 plant visits 12.0 Laboratory computational laboratory 12.0 Lectures 24.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments (continuous assessment) 20.0 1,2 Examination 50.0 1,2,3 Laboratory reports 5.0 2,3 Test (test/quiz) 25.0 1,2
Required/recommended reading and online materials	Felder and Rousseau: Elementary Principles of Chemical Processes
Course Website	NIL
Additional Course Information	Laboratory courses are mandatory.  Students must complete ALL experiments and laboratory reports to pass this course.

CHEM3143 Introduction to materials chemistry (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	60
Course Co-ordinator	Prof Y F Wang, Chemistry < wanglab@hku.hk >
Teachers Involved	(Prof Y F Wang,Chemistry)
Course Objectives	This course provides an introduction to materials chemistry. The goal is to present the fundamental knowledge of various types of materials including their structure, synthesis, and properties.  This course is essential for students who wish to take advanced materials course.
Course Contents & Topics	Classification of materials; structure of crystalline solids; phases and phase transformation; defects and mechanical properties; alloys and ceramics; introduction to soft matter; structure, synthesis, and properties of polymers; colloids; liquid crystals; viscoelasticity; applications of materials; characterization techniques.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 describe different materials classification and their composition, structures, and properties, and to apprehend the concept of structure/property relationship CLO 2 explain different structures and phases, phase transformation in solid materials CLO 3 understand defects in crystalline solid materials and relate them with mechanical properties CLO 4 appreciate soft materials and some examples and characteristics CLO 5 understand the concept of molecular weight distribution in polymers, and explain the effect of polymerization kinetics to their properties CLO 6 identify examples of some important materials, and explain their structure-property relationship CLO 7 demonstrate knowledge in materials characterizations
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM2441; and Pass in CHEM2541 or CHEM2341
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry (Intensive) ( Core/Compulsory ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry (Intensive) ( Core/Compulsory ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry (Intensive) ( Core/Compulsory ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry (Intensive) ( Core/Compulsory ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry (Intensive) ( Core/Compulsory ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry (Intensive) < PLO 1,2,3 > 2024 Major in Chemistry (Intensive) < PLO 1,2,3 > 2023 Major in Chemistry (Intensive) < PLO 1,2,3 > 2022 Major in Chemistry (Intensive) < PLO 1,2,3 > 2021 Major in Chemistry (Intensive) < PLO 1,2,3 >
Offer in 2025 - 2026	Y        1st sem	Examination	Dec
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough knowledge of essential facts, concepts, principles, and theories related to classification of materials. Show deep understanding of materials structures at different length scales and the relationship with materials properties particularly for classical solid materials and soft materials. Show extensive knowledge in synthesis, characterization and applications of common polymers. Demonstrate strong ability to apply/integrate knowledge and theory related to the synthesis and applications of materials. Show strong ability to analyze novel problems and critical use of data/experimental results to draw appropriate and insightful conclusions related to materials synthesis/characterization. B Demonstrate thorough knowledge of essential facts, concepts, principles, and theories related to classification of materials. Show deep understanding of materials structures at different length scales and the relationship with materials properties particularly for classical solid materials and soft materials. Show extensive knowledge in synthesis, characterization and applications of common polymers. Demonstrate evidence to apply/integrate knowledge and theory related to the synthesis and applications of materials. Show evidence to analyze novel problems and critical use of data/experimental results to draw appropriate and insightful conclusions related to materials synthesis/characterization. C Demonstrate general but incomplete command of knowledge of essential facts, concepts, principles, and theories related to classification of materials. Show some but insufficient understanding of materials structures at different length scales and the relationship with materials properties particularly for classical solid materials and soft materials. Show some knowledge in synthesis, characterization and applications of common polymers. Demonstrate evidence to apply/integrate knowledge and theory related to the synthesis and applications of materials. Show ability to analyze problems to most familiar situations and mostly correct but erroneous use of data/experimental results to draw appropriate conclusions related to materials synthesis/characterization. D Demonstrate partial but limited command of knowledge of essential facts, concepts, principles, and theories related to classification of materials. Show deep understanding of materials structures at different length scales and the relationship with materials properties particularly for classical solid materials and soft materials. Show limited knowledge in synthesis, characterization and applications of common polymers. Demonstrate evidence but limited ability to apply/integrate knowledge and theory related to the synthesis and applications of materials. Show limited ability to analyze problems to most familiar situations and mostly correct but erroneous use of data/experimental results to draw appropriate conclusions related to materials synthesis/characterization. Fail Demonstrate little or no evidence of command of knowledge of essential facts, concepts, principles, and theories related to classification of materials. Show little or no understanding of materials structures at different length scales and the relationship with materials properties particularly for classical solid materials and soft materials. Show little or no knowledge in synthesis, characterization and applications of common polymers. Demonstrate limited or no evidence of ability to apply/integrate knowledge and theory related to the synthesis and applications of materials. Show little or no ability to analyze novel problems and use of data/experimental results to draw appropriate and insightful conclusions related to materials synthesis/characterization.
Communication-intensive Course	N
Course Type	Lecture-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Lectures 36.0 Tutorials 12.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Examination 50.0 1,2,3,4,5,6,7 Test (mid-term tests and assignments) 50.0 1,2,3,4,5,6,7
Required/recommended reading and online materials	W. D. Callister: Materials Science and Engineering: An Introduction (8th or 9th edition) F. W. Billmeyer: Textbook of Polymer Science (John Wiley and Sons, 1984) G. Odian: Principles of Polymerizations (John Wiley and Sons, 2004) M. P. Stevens: Polymer Chemistry: An Introduction (Oxford University Press, 1999)
Course Website	NIL
Additional Course Information	NIL

CHEM3144 Fundamentals of Nuclear Magnetic Resonance (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	40
Course Co-ordinator	Dr K K H Ng, Chemistry < kkhn3@hku.hk >
Teachers Involved	(Dr K K H Ng,Chemistry) (Prof X Y Chen,Chemistry)
Course Objectives	Nuclear magnetic resonance (NMR) spectroscopy is one of the most powerful and versatile analytical techniques for chemists studying the conformational, structural, and dynamic properties of a wide range of materials: from small organic molecules, organometallic species, up to macromolecules and polymers. However, the associated theories and concepts in NMR can appear formidable.  As a consequence, a modern NMR spectrometer is often treated as a 'black box', which could lead to the inadvertent generation of artefacts and misinterpretation of experimental data. This course aims to provide students with both the fundamental theories of NMR spectroscopy and hands-on training at the spectrometer, thus allowing them to gain a genuine understanding of the subject, and be competent in setting up experiments and obtaining reliable data independently.
Course Contents & Topics	In this course, we will explore the capabilities of the NMR ‘black box’ and develop a deeper understanding of the physical origins of the phenomenon of magnetic resonance. Building upon the basic theory of nuclear magnetism, we shall employ the semi-classical vector model and cover topics from chemical shifts and scalar couplings to more advanced concepts like the nuclear Overhauser effect (nOe), relaxation, dynamic NMR, and polarisation transfer. We will also develop a qualitative understanding of basic NMR pulse sequences, which are at the heart of modern NMR spectroscopy. In parallel, students will gain hands-on experience at the spectrometer during the laboratory sessions, performing a range of NMR experiments.  These include simple 1D acquisitions, heteronuclear decoupling, selective excitation, nOe, and 2D experiments.  The course emphasises the practical aspects of NMR experiments, focusing on how to acquire valid and reliable data.  Data processing techniques will also be introduced.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 account for the theoretical foundation of NMR spectroscopy and relate NMR parameters such as chemical shift, scalar coupling constants, and relaxation time constants to molecular structure CLO 2 analyse and understand commonly employed one-dimensional NMR pulse sequences using basic NMR theory CLO 3 select suitable NMR experiments for structure elucidation of organic and organometallic complexes and investigation of dynamic equilibria CLO 4 perform common NMR experiments and analyse, interpret, present and document the results
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM2241 or CHEM2341 or CHEM2441 or CHEM2541
Course Status with Related Major/Minor /Professional Core	2U000C00 Course not offered under any Major/Minor/Professional core 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping
Offer in 2025 - 2026	Y        2nd sem	Examination	May
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate a thorough grasp of the knowledge and skills required in both theory and laboratory work regarding nuclear magnetic resonance spectroscopy as described in the course learning outcomes. Show strong analytical abilities, critical and logical thinking and capability to apply and integrate knowledge learnt to solve related issues and problems. Display highly effective organisation and presentation skills during assessments. B Demonstrate substantial knowledge and skills required in both theory and laboratory work for attaining at least most of the course learning outcomes. Show reasonable analytical abilities, critical and logical thinking and capability to apply and integrate knowledge learnt to solve related issues and problems. Display effective organisation and presentation skills during assessments. C Demonstrate general but incomplete command of knowledge and skills required in theory and laboratory work required for attaining most of the course learning outcomes. Show analytical abilities, critical and logical thinking and capability to apply and integrate knowledge learnt to solve related issues and problems. Display some organisation and presentation skills during assessments. D Demonstrate partial and limited command of knowledge and skills required in theory and laboratory work for attaining some of the course learning outcomes. Show limited analytical abilities, critical and logical thinking and capability to apply and integrate knowledge learnt to solve related issues and problems. Display poor organisation and presentation skills during assessments. Fail Demonstrate little or no evidence of command of knowledge and skills required in theory and laboratory work for attaining the course learning outcomes. Show little analytical abilities, critical and logical thinking and capability to apply and integrate knowledge learnt to solve related issues and problems. Display lack of organisation and presentation skills during assessments.
Communication-intensive Course	N
Course Type	Lecture with laboratory component course
Course Teaching & Learning Activities	Activities Details No. of Hours Laboratory 24.0 Lectures 24.0 Tutorials 8.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Examination 40.0 1,2,3 Laboratory reports 20.0 1,3 Project report 25.0 1,2,3,4 Test 15.0 1,2,3
Required/recommended reading and online materials	P. J. Hore: Nuclear Magnetic Resonance (Oxford University Press, 2nd Edition, 2015) James Keeler: Understanding NMR Spectroscopy (Wiley, 2nd Edition, 2010) David P. Goldenberg: Principles of NMR Spectroscopy: An Illustrated Guide (University Science Books, 2016)
Course Website	NIL
Additional Course Information	References to specialized texts and other published materials will be made throughout the course.

   <<< This course is not offered in 2025-2026. Course details are subject to change. >>>

CHEM3146 Principles and applications of spectroscopic and analytical techniques (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	200
Course Co-ordinator	Dr X Li, Chemistry < xiangli@hku.hk >
Teachers Involved
Course Objectives	To cover the principles and applications of modern practical spectroscopic and analytical techniques. This course is a pre-requisite for the advanced chemistry courses.
Course Contents & Topics	UV-Visible Absorption Spectroscopy, Nuclear Magnetic Resonance Spectroscopy, Mass Spectrometry, Infra-red Spectroscopy, Elemental Analysis, Molecular Formulas and analysis of data.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 understand the basic principles and applications of IR, UV/Vis, MS and NMR spectroscopic techniques CLO 2 describe and explain the terminology of IR, UV/Vis, MS and NMR spectroscopies CLO 3 perform chemical structure elucidation and analysis based on UV/Vis, MS and NMR spectroscopic data
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in any CHEM2XXX level course
Course Status with Related Major/Minor /Professional Core	2U000C00 Course not offered under any Major/Minor/Professional core 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping
Offer in 2025 - 2026	N	Examination
Offer in 2026 - 2027	N
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough mastery at an advanced level of extensive knowledge and skills required for attaining all the course learning outcomes. Show strong analytical and critical abilities and logical thinking, and ability to apply knowledge to a wide range of complex, familiar and unfamiliar situations. B Demonstrate substantial command of a broad range of knowledge and skills required for attaining at least most of the course learning outcomes. Show evidence of analytical and critical abilities and logical thinking, and ability to apply knowledge to familiar and some unfamiliar situations. C Demonstrate general but incomplete command of knowledge and skills required for attaining most of the course learning outcomes. Show evidence of some analytical and critical abilities and logical thinking, and ability to apply knowledge to most familiar situations. D Demonstrate partial but limited command of knowledge and skills required for attaining some of the course learning outcomes. Show evidence of some coherent and logical thinking, but with limited analytical and critical abilities. Show limited ability to apply knowledge to solve problems. Fail Demonstrate little or no evidence of command of knowledge and skills required for attaining the course learning outcomes. Lack of analytical and critical abilities, logical and coherent thinking. Show very little or no ability to apply knowledge to solve problems.
Communication-intensive Course	N
Course Type	Lecture-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Lectures 36.0 Tutorials 12.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments 15.0 1,2,3 Examination 70.0 1,2,3 Test (2 quizzes) 15.0 1,2,3
Required/recommended reading and online materials	Donald L. Pavia, Gary M. Lampman, George S. Kriz: Introduction to Spectroscopy (Thomson Learning, 2001, 3rd & 4th edition) W. Kemp: Organic Spectroscopy (Macmillan, 1991, 3rd ed.)
Course Website	NIL
Additional Course Information	Suggested follow-up course: CHEM3241

CHEM3241 Analytical chemistry II: chemical instrumentation (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	80
Course Co-ordinator	Prof Y Li, Chemistry < yingli0e@hku.hk >
Teachers Involved	(Prof I K Chu,Chemistry) (Prof Y Li,Chemistry)
Course Objectives	To cover the basic principles and applications of chemical instrumentation. This course aims to provide working knowledge, in addition to the principles, of instruments that are commonly used in chemical laboratories.
Course Contents & Topics	Optical methods: Beer's Law; UV-visible, infrared, and atomic spectrometry; fluorescence; atomic mass spectrometry; grating spectrometer; photon detectors and thermal detectors. Separation methods: partition; chromatography theories; high performance liquid chromatography (HPLC) and gas chromatography (GC); instrumental set up of HPLC and GC. Mass spectrometry: fundamental concept of mass spectrometry; electrospray ionization (ESI) and matrix-assisted laser desorption ionization (MALDI); time-of-flight (TOF) and quadrupole (Q) mass analyzers.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 explain the principles of the optical methods, separation methods, and mass spectrometry CLO 2 describe the basic experimental set up and the properties of the basic components of the instruments used in the laboratory classes CLO 3 apply experimental skills in chemical analysis including sample preparation, standard solution preparation, instrument calibration, and matrix effects correction (standard additions)
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM2241
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry ( Core/Compulsory ) 2025 Major in Chemistry (Intensive) ( Core/Compulsory ) 2025 Major in Environmental Science ( Disciplinary Elective ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Core/Compulsory ) 2024 Major in Chemistry (Intensive) ( Core/Compulsory ) 2024 Major in Environmental Science ( Disciplinary Elective ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Core/Compulsory ) 2023 Major in Chemistry (Intensive) ( Core/Compulsory ) 2023 Major in Environmental Science ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Core/Compulsory ) 2022 Major in Chemistry (Intensive) ( Core/Compulsory ) 2022 Major in Environmental Science ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Core/Compulsory ) 2021 Major in Chemistry (Intensive) ( Core/Compulsory ) 2021 Major in Environmental Science ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective ) 2021 Minor in Environmental Science ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry < PLO 2,3,4,5 > 2025 Major in Chemistry (Intensive) < PLO 2,3,4,5 > 2025 Major in Environmental Science < PLO 2,3,4 > 2024 Major in Chemistry < PLO 2,3,4,5 > 2024 Major in Chemistry (Intensive) < PLO 2,3,4,5 > 2024 Major in Environmental Science < PLO 2,3,4 > 2023 Major in Chemistry < PLO 2,3,4,5 > 2023 Major in Chemistry (Intensive) < PLO 2,3,4,5 > 2023 Major in Environmental Science < PLO 2,3,4 > 2022 Major in Chemistry < PLO 2,3,4,5 > 2022 Major in Chemistry (Intensive) < PLO 2,3,4,5 > 2022 Major in Environmental Science < PLO 2,3,4 > 2021 Major in Chemistry < PLO 2,3,4,5 > 2021 Major in Chemistry (Intensive) < PLO 2,3,4,5 > 2021 Major in Environmental Science < PLO 2,3,4 >
Offer in 2025 - 2026	Y        1st sem	Examination	Dec
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A - Demonstrate thorough grasp of the subject. - Show evidence of strong analytical abilities, logical and independent thinking, and ablility to apply knowledge to a wide range of complex, familiar and unfamiliar situations. - Demonstrate highly proficient lab skills and techniques and critical use of data and results to draw appropriate and insightful conclusions. - Demonstrate highly effective organization and presentation skills B - Demonstrate substantial grasp of the subject. - Show evidence of analytical abilities and logical thinking, some evidence of independent thinking, and ability to apply knowledge to familiar and some unfamiliar situations. - Demonstrate proficient lab skills and techniques and correct use of data and results to draw appropriate conclusions. - Demonstrate effective organization and presentation skills. C - Demonstrate general but incomplete grasp of the subject. - Show evidence of some analytical abilities and logical thinking, little evidence of independent thinking, and ability to apply knowledge to most familiar situations. - Demonstrate adequate lab skills and techniques and mostly correct but some erroneous use of data and results to draw appropriate conclusions. - Demonstrate moderately effective organization and presentation skills. D - Demonstrate partial but limited grasp, with retention of some relevant information, of the subject. - Show evidence of limited analytical abilities, little or no evidence of independent thinking, and limited ability to apply knowledge to solve problems. - Demonstrate partially effective lab skills and techniques and limited ability to use data and results to draw appropriate conclusions. - Demonstrate limited or barely effective organization and presentation skills. Fail - Demonstrate little or no grasp of the knowledge and understanding of the subject. - Show little or no evidence of analytical abilities, logical and independent thinking, and very little or no ability to apply knowledge to solve problems. - Demonstrate minimally effective or ineffective lab skills and techniques and misuse of data and results and/or unable to draw appropriate conclusions. - Demonstrate incoherent organization and poor presentation skills.
Communication-intensive Course	N
Course Type	Lecture with laboratory component course
Course Teaching & Learning Activities	Activities Details No. of Hours Laboratory 28.0 Lectures 24.0 Tutorials 6.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments in-class practise, in-class quiz 12.0 1,2,3 Examination 50.0 1,2,3 Laboratory reports 24.0 1,2,3 Test Midterm 14.0 1,2,3
Required/recommended reading and online materials	D.A. Skoog, F.K. Holler, S.R. Crouch: Principles of Instrumental Analysis (Thomson, latest edition). D.A. Skoog, D.M. West, F.J. Holler, and S.R. Crouch: Fundamentals of Analytical Chemistry (Thomson, latest edition)
Course Website	NIL
Additional Course Information	Laboratory classes are mandatory.  Students must complete ALL experiments and laboratory reports to pass this course.

CHEM3242 Food and water analysis (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	50
Course Co-ordinator	Dr K K H Ng, Chemistry < kkhn3@hku.hk >
Teachers Involved	(Dr K K H Ng,Chemistry)
Course Objectives	To cover areas in the application and new methodology development in analytical chemistry with focus on food and water analysis.
Course Contents & Topics	Chemical Analysis in Practicing Laboratories: Use of standard methods, guidelines and standards for food and water analysis; good laboratory practice; reliability and quality issues in chemical analysis. Food Analysis: Requirement of nutritional labeling; determination of food nutritional value (e.g. total protein content, sodium content); detection of food adulteration and contamination (e.g. presence of banned additives, toxins, undeclared components); recent issues and case studies in food analysis. Water Analysis: Water quality standards; sampling, pretreatment, storage of water samples; theory and technologies for field, laboratory and automated analysis of selected types of water (e.g. drinking water, recreational water, waste water). Analytical Method Development: Selection, application and combination of analytical (e.g. sample digestion, solid phase extraction) and instrumental (e.g. GC, LC, MS) techniques for food and water analysis; method validation (e.g. recovery analysis, analysis of certified reference materials)
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 identify and communicate the importance of chemical analysis in ensuring food and water safety, and in safeguarding public health CLO 2 describe and explain the working principles of the various analytical techniques in food and water analysis using both written and oral formats CLO 3 analyse and present the strengths and limitations of various analytical techniques and select an appropriate, "fit-for-purpose" method CLO 4 implement various analytical techniques used in practicing food and water laboratories CLO 5 collect experimental data, perform subsequent analyses, interpret and present the results to peers using both written and oral formats
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM2241 or CHEM2341 or CHEM2441 or CHEM2541. Please note that School of Biological Sciences stipulates that students who have passed CHEM3242 are not allowed to take BIOL3209 Food and nutrient analysis.
Course Status with Related Major/Minor /Professional Core	2U000C00 Course not offered under any Major/Minor/Professional core 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping
Offer in 2025 - 2026	Y        2nd sem	Examination	May
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate through a thorough grasp of the knowledge and skills required in theory and laboratory work in food and water analysis to acquire accurate results with full interpretation for analytical application as described in all the course learning outcomes. Show strong analytical and critical abilities, logical thinking and capability to apply knowledge learnt to solve a wide range of complex issues and problems related to the analysis of food and water. Apply highly effective organization and presentation skills as shown in class work. B Demonstrate a substantial command of a broad range of knowledge and skills required for attaining at least most of the course learning outcomes. Show evidence of analytical and critical abilities, logical thinking, and capability to apply knowledge learnt to solve a wide range of complex issues and problems related to the analysis of food and water. Apply effective organization and presentation skills as shown in class work. C Demonstrate a general command of knowledge and skills required for attaining most of the course learning outcomes. Show evidence of analytical and critical abilities, logical thinking, and ability to apply knowledge learnt to solve a wide range of complex issues and problems related to the analysis of food and water. Apply effective organization and presentation skills as shown in class work. D Demonstrate a partial but limited command of knowledge and skills required for attaining some of the course learning outcomes in Food and Water Analysis. Show evidence of some coherent and logical thinking, but with limited analytical and critical abilities. Show limited ability to apply knowledge to solve problems related to the analysis of food and water. Apply limited or barely effective organization and presentation skill as shown in class work. Fail Demonstrate little or no evidence for the command of knowledge and skills required for attaining the course learning outcomes. Lack of analytical and critical abilities, logical and coherent thinking. Show very little or no ability to apply knowledge to solve problems related to the analysis of food and water. Organization and presentation skills are minimally effective or ineffective as shown in class work.
Communication-intensive Course	Y
Course Type	Lecture with laboratory component course
Course Teaching & Learning Activities	Activities Details No. of Hours Laboratory 16.0 Lectures 24.0 Tutorials 8.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments 10.0 1,2,3 Examination 35.0 2,3,4 Laboratory reports (experiment & lab report) 25.0 1,2,4,5 Presentation (Project with presentation) 20.0 1,2,3,5 Test 10.0 2,3,4
Required/recommended reading and online materials	D. A. Skoog, D. M. West, F. J. Holler, S. R. Crouch: Fundamentals of Analytical Chemistry (Cengage Learning, 10e) D. C. Harris, C. A. Lucy:  Quantitative Chemical Analysis (W. H. Freeman, 10e) S. S. Nielsen (ed.): Food Analysis (Springer, 5e)
Course Website	NIL
Additional Course Information	Laboratory classes are mandatory.  Students must complete ALL experiments and laboratory reports to pass this course.

   <<< This course is not offered in 2025-2026. Course details are subject to change. >>>

CHEM3243 Introductory instrumental chemical analysis (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	30
Course Co-ordinator	Dr X Li, Chemistry < xiangli@hku.hk >
Teachers Involved	(Dr K C J Wong,Pharmacology and Pharmacy) (Dr X Li,Chemistry)
Course Objectives	This course is designed for non-chemistry major students covering basic principles of separation and spectroscopy for chemical analysis.  This course provides a general foundation for further studies in pharmacology, life and environmental sciences.
Course Contents & Topics	Optical methods: Beer's Law; UV-visible, infrared, and atomic spectrometry; fluorescence; atomic mass spectrometry; grating spectrometer; photon detectors and thermal detectors. Separation methods: partition; chromatography theories; high performance liquid chromatography (HPLC) and gas chromatography (GC); instrumental set up of HPLC and GC. Mass spectrometry: fundamental concept of mass spectrometry; electrospray ionization (ESI) and matrix-assisted laser desorption ionization (MALDI); time-of-flight (TOF) and quadrupole (Q) mass analyzers. NMR: basic principle of nuclear magnetic resonance. Analysis and quality assurance: statistical analysis of small sets of data, control chart.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 explain the principles of the optical methods, separation methods, mass spectrometry, and NMR CLO 2 describe the basic experimental set up and the properties of the basic components of the instruments used in the laboratory classes
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM2041 or CHEM2241; and Not for students who have passed CHEM3241, or have already enrolled in this course.
Course Status with Related Major/Minor /Professional Core	2U000C00 Course not offered under any Major/Minor/Professional core 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping
Offer in 2025 - 2026	N	Examination
Offer in 2026 - 2027	N
Course Grade	A+ to F
Grade Descriptors	A - Demonstrate thorough grasp of the subject. - Show evidence of strong analytical abilities, logical and independent thinking, and ablility to apply knowledge to a wide range of complex, familiar and unfamiliar situations. - Demonstrate highly proficient lab skills and techniques and critical use of data and results to draw appropriate and insightful conclusions. - Demonstrate highly effective organization and presentation skills. B - Demonstrate substantial grasp of the subject. - Show evidence of analytical abilities and logical thinking, some evidence of independent thinking, and ability to apply knowledge to familiar and some unfamiliar situations. - Demonstrate proficient lab skills and techniques and correct use of data and results to draw appropriate conclusions. - Demonstrate effective organization and presentation skills. C - Demonstrate general but incomplete grasp of the subject. - Show evidence of some analytical abilities and logical thinking, little evidence of independent thinking, and ability to apply knowledge to most familiar situations. - Demonstrate adequate lab skills and techniques and mostly correct but some erroneous use of data and results to draw appropriate conclusions. - Demonstrate moderately effective organization and presentation skills. D - Demonstrate partial but limited grasp, with retention of some relevant information, of the subject. - Show evidence of limited analytical abilities, little or no evidence of independent thinking, and limited ability to apply knowledge to solve problems. - Demonstrate partially effective lab skills and techniques and limited ability to use data and results to draw appropriate conclusions. - Demonstrate limited or barely effective organization and presentation skills. Fail - Demonstrate little or no grasp of the knowledge and understanding of the subject. - Show little or no evidence of analytical abilities, logical and independent thinking, and very little or no ability to apply knowledge to solve problems. - Demonstrate minimally effective or ineffective lab skills and techniques and misuse of data and results and/or unable to draw appropriate conclusions. - Demonstrate incoherent organization and poor presentation skills.
Communication-intensive Course	N
Course Type	Lecture with laboratory component course
Course Teaching & Learning Activities	Activities Details No. of Hours Laboratory 28.0 Lectures 24.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Examination 70.0 1,2 Laboratory reports 15.0 1,2 Test 15.0 1,2
Required/recommended reading and online materials	D.A. Skoog, F.K. Holler, S.R. Crouch: Principles of Instrumental Analysis (Thomson, latest edition). D.A. Skoog, D.M. West, F.J. Holler, and S.R. Crouch: Fundamentals of Analytical Chemistry (Thomson, latest edition)
Course Website	NIL
Additional Course Information	Laboratory classes are mandatory.  Students must complete ALL experiments and laboratory reports to pass this course.

   <<< This course is not offered in 2025-2026. Course details are subject to change. >>>

CHEM3244 Analytical techniques for pharmacy students (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	35
Course Co-ordinator	Dr X Li, Chemistry < xiangli@hku.hk >
Teachers Involved	(Dr K C J Wong,Pharmacology and Pharmacy) (Dr X Li,Chemistry)
Course Objectives	The course covers theories and practicals on various analytical techniques used in pharmaceutical industry. Sampling and data analysis, method validation with respect to regulatory guidelines, ultraviolet/visible, infrared, fluorescence, atomic spectrophotometry, separation techniques such as gas chromatography and liquid chromatography, and modern mass spectrometry with its applications in protein sequencing will be covered in this course.
Course Contents & Topics	Principles and applications of different analytical and measurement techniques in pharmaceutical sciences. Analysis and quality assurance: method validation, sampling, statistics, hypothesis tests Optical spectroscopy: Beer's law, UV/Vis, infrared, fluorescence, and atomic spectroscopy Separation and purification: gas chromatography and liquid chromatography Modern mass spectrometry: ionization techniques (ESI, MALDI), mass analysis techniques (TOF, quadrupole), protein sequencing.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 demonstrate knowledge and understanding of principles of data analysis, optical spectroscopic methods, separation techniques, and modern mass spectrometry CLO 2 describe the basic experimental setup and the properties of the basic components of the instruments used in the laboratory classes CLO 3 apply experimental skills in experiments including sample preparation, standard solution preparation, instrument calibration, and matrix effect correction
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in BPHM2136 (This course is for BPharm students only)
Course to PLO Mapping
Offer in 2025 - 2026	N	Examination
Offer in 2026 - 2027	N
Course Grade	A+ to F
Grade Descriptors	A - Demonstrate thorough grasp of the subject. - Show evidence of strong analytical abilities, logical and independent thinking, and ablility to apply knowledge to a wide range of complex, familiar and unfamiliar situations. - Demonstrate highly proficient lab skills and techniques and critical use of data and results to draw appropriate and insightful conclusions. - Demonstrate highly effective organization and presentation skills. B - Demonstrate substantial grasp of the subject. - Show evidence of analytical abilities and logical thinking, some evidence of independent thinking, and ability to apply knowledge to familiar and some unfamiliar situations. - Demonstrate proficient lab skills and techniques and correct use of data and results to draw appropriate conclusions. - Demonstrate effective organization and presentation skills. C - Demonstrate general but incomplete grasp of the subject. - Show evidence of some analytical abilities and logical thinking, little evidence of independent thinking, and ability to apply knowledge to most familiar situations. - Demonstrate adequate lab skills and techniques and mostly correct but some erroneous use of data and results to draw appropriate conclusions. - Demonstrate moderately effective organization and presentation skills. D - Demonstrate partial but limited grasp, with retention of some relevant information, of the subject. - Show evidence of limited analytical abilities, little or no evidence of independent thinking, and limited ability to apply knowledge to solve problems. - Demonstrate partially effective lab skills and techniques and limited ability to use data and results to draw appropriate conclusions. - Demonstrate limited or barely effective organization and presentation skills. Fail - Demonstrate little or no grasp of the knowledge and understanding of the subject. -.Show little or no evidence of analytical abilities, logical and independent thinking, and very little or no ability to apply knowledge to solve problems. - Demonstrate minimally effective or ineffective lab skills and techniques and misuse of data and results and/or unable to draw appropriate conclusions. - Demonstrate incoherent organization and poor presentation skills.
Communication-intensive Course	N
Course Type	Lecture with laboratory component course
Course Teaching & Learning Activities	Activities Details No. of Hours Laboratory 28.0 Lectures 24.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Examination 70.0 1,2,3 Laboratory reports 15.0 1,2,3 Test 15.0 1,2,3
Required/recommended reading and online materials	D.A. Skoog, F.K. Holler, S.R. Crouch: Principles of Instrumental Analysis (Thomson, latest edition). D.A. Skoog, D.M. West, F.J. Holler, and S.R. Crouch: Fundamentals of Analytical Chemistry (Thomson, latest edition).
Course Website	NIL
Additional Course Information	This course is for Pharmacy students ONLY. Laboratory classes are mandatory.  Students must complete ALL experiments and laboratory reports to pass this course.

CHEM3341 Inorganic chemistry II (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	90
Course Co-ordinator	Dr A M Y Yuen, Chemistry < maiyan@hku.hk >
Teachers Involved	(Dr A M Y Yuen,Chemistry) (Prof V W W Yam,Chemistry)
Course Objectives	This course is a continuation from CHEM2341 Inorganic Chemistry I, with a more detailed treatment of general inorganic chemistry, with examples relevant to biological processes and material science, suited to the needs of those intending to extend their studies in chemistry.
Course Contents & Topics	Chemistry of selected classes of inorganic, coordination and organometallic compounds including mechanisms of their reaction where appropriate. Structure, bonding, magnetism and spectral properties of inorganic systems including examples in bioinorganic systems.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 demonstrate knowledge of chemistry of selected classes of inorganic, coordination and organometallic compounds CLO 2 understand structure, bonding, magnetism and spectral properties of inorganic systems CLO 3 understand mechanisms of selected chemical reactions that are essential to coordination and organometallic compounds CLO 4 gain appropriate knowledge of coordination compounds in biological systems
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM2341
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry ( Core/Compulsory ) 2025 Major in Chemistry (Intensive) ( Core/Compulsory ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Core/Compulsory ) 2024 Major in Chemistry (Intensive) ( Core/Compulsory ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Core/Compulsory ) 2023 Major in Chemistry (Intensive) ( Core/Compulsory ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Core/Compulsory ) 2022 Major in Chemistry (Intensive) ( Core/Compulsory ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Core/Compulsory ) 2021 Major in Chemistry (Intensive) ( Core/Compulsory ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry < PLO 2,3,4 > 2025 Major in Chemistry (Intensive) < PLO 2,3,4 > 2024 Major in Chemistry < PLO 2,3,4 > 2024 Major in Chemistry (Intensive) < PLO 2,3,4 > 2023 Major in Chemistry < PLO 2,3,4 > 2023 Major in Chemistry (Intensive) < PLO 2,3,4 > 2022 Major in Chemistry < PLO 2,3,4 > 2022 Major in Chemistry (Intensive) < PLO 2,3,4 > 2021 Major in Chemistry < PLO 2,3,4 > 2021 Major in Chemistry (Intensive) < PLO 2,3,4 >
Offer in 2025 - 2026	Y        1st sem	Examination	Dec
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough knowledge and understanding of essential facts, concepts, principles, and theories relating to the more advanced foundation knowledge of inorganic chemistry, especially those related to structure and bonding of inorganic, coordination and organometallic compounds; mechanisms of reactions; and magnetic and spectral properties of inorganic systems including examples in bioinorganic systems. Show strong ability to apply and integrate knowledge and theory relating to the more advanced foundation knowledge of inorganic chemistry. Show strong ability to analyze novel problems and critical use of data and experimental results to draw appropriate and insightful conclusions relating to the essential and more advanced foundation principles and knowledge of inorganic chemistry. Demonstrate highly effective laboratory skills and techniques, especially in the synthesis and reactivity study of inorganic compounds and metal complexes, and their characterization by various spectroscopic methods. B Demonstrate substantial command of knowledge and understanding of essential facts, concepts, principles, and theories relating to the more advanced foundation knowledge of inorganic chemistry, especially those related to structure and bonding of inorganic, coordination and organometallic compounds; mechanisms of reactions; and magnetic and spectral properties of inorganic systems including examples in bioinorganic systems. Show evidence to apply and integrate knowledge and theory relating to the more advanced foundation knowledge of inorganic chemistry. Show evidence to analyze novel problems and correct use of data and experimental results to draw appropriate conclusions relating to the essential and more advanced foundation principles and knowledge of inorganic chemistry. Demonstrate effective laboratory skills and techniques, especially in the synthesis and reactivity study of inorganic compounds and metal complexes, and their characterization by various spectroscopic methods. C Demonstrate general but incomplete command of knowledge and understanding of essential facts, concepts, principles, and theories relating to the more advanced foundation knowledge of inorganic chemistry, especially those related to structure and bonding of inorganic, coordination and organometallic compounds; mechanisms of reactions; and magnetic and spectral properties of inorganic systems including examples in bioinorganic systems. Show evidence of some abilities to apply and integrate knowledge and theory relating to the more advanced foundation knowledge of inorganic chemistry. Show ability to analyze problems to most familiar situations and mostly correct but erroneous use of data and experimental results to draw appropriate conclusions relating to the essential and more advanced foundation principles and knowledge of inorganic chemistry. Demonstrate moderately effective laboratory skills and techniques, especially in the synthesis and reactivity study of inorganic compounds and metal complexes, and their characterization by various spectroscopic methods. D Demonstrate partial but limited command of knowledge and understanding of essential facts, concepts, principles, and theories relating to the more advanced foundation knowledge of inorganic chemistry, especially those related to structure and bonding of inorganic, coordination and organometallic compounds; mechanisms of reactions; and magnetic and spectral properties of inorganic systems including examples in bioinorganic systems. Show evidence of limited abilities to apply and integrate knowledge and theory relating to the more advanced foundation knowledge of inorganic chemistry. Show limited ability to analyze problems to most familiar situations and mostly correct but erroneous use of data and experimental results to draw appropriate conclusions relating to the essential and more advanced foundation principles and knowledge of inorganic chemistry. Demonstrate partially effective laboratory skills and techniques, especially in the synthesis and reactivity study of inorganic compounds and metal complexes, and their characterization by various spectroscopic methods. Fail Demonstrate little or no evidence of command of knowledge and understanding of essential facts, concepts, principles, and theories relating to the more advanced foundation knowledge of inorganic chemistry, especially those related to structure and bonding of inorganic, coordination and organometallic compounds; mechanisms of reactions; and magnetic and spectral properties of inorganic systems including examples in bioinorganic systems. Show little or no evidence of abilities to apply and integrate knowledge and theory relating to the more advanced foundation knowledge of inorganic chemistry. Show little or no ability to analyze problems to most familiar situations and erroneous use of data and experimental results to draw appropriate conclusions relating to the essential and more advanced foundation principles and knowledge of inorganic chemistry. Demonstrate minimally effective laboratory skills and techniques, especially in the synthesis and reactivity study of inorganic compounds and metal complexes, and their characterization by various spectroscopic methods.
Communication-intensive Course	N
Course Type	Lecture with laboratory component course
Course Teaching & Learning Activities	Activities Details No. of Hours Laboratory 24.0 Lectures 24.0 Tutorials 6.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments 18.0 1,2,3,4 Examination 50.0 1,2,3,4 Laboratory reports 12.0 1,2,3,4 Test 20.0 1,2,3,4
Required/recommended reading and online materials	Shriver & Atkins, Inorganic Chemistry (7th Edition), Oxford University Press, 2018 Catherine, Housecroft & Sharpe, Inorganic Chemistry (5th Edition), Prentice Hall, 2018
Course Website	NIL
Additional Course Information	Laboratory classes are mandatory.  Students must complete ALL experiments and laboratory reports to pass this course.

CHEM3342 Bioinorganic chemistry (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	50
Course Co-ordinator	Prof H Z Sun, Chemistry < hsun@hku.hk >
Teachers Involved	(Dr A T L Li,Chemistry) (Prof H Z Sun,Chemistry)
Course Objectives	This course is a continuation from Basic Inorganic Chemistry and Basic Organic Chemistry, giving further and more details of inorganic chemistry in biological system, with examples relevance to biological processes and medical science, suited to the needs of those intending to extend their studies in (bio)chemistry and biomedical science.
Course Contents & Topics	Bioinorganic Chemistry of selected topics of interest. Examples include the inorganic chemistry (and biochemistry) behind the requirement of biological cells for metals such as zinc, iron and copper; and metals in medicine such as mechanisms by which organisms obtain required metal ions from their environment, and use of metal-containing compounds in treating diseases such as cancer.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 understand the principles and concepts of inorganic/organic chemistry in biological system CLO 2 understand structure, bonding, and spectral properties of selected metals in proteins and nucleic acids CLO 3 understand chemical mechanisms of selected metal homeostasis (i.e. uptake, transport and storage) CLO 4 understand the role of metal complexes medicine
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM2341
Course Status with Related Major/Minor /Professional Core	2U000C00 Course not offered under any Major/Minor/Professional core 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping
Offer in 2025 - 2026	Y        2nd sem	Examination	May
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough knowledge and understanding of essential facts, concepts, principles, and theories relating to the basic foundation knowledge of bioinorganic chemistry, especially those related to hard-soft acid-base theory; chelation; structure and bonding of metals in biological systems; thermodynamic and kinetic aspects of metal ions in biological processes and their relevance to metal homeostasis; metal-based drugs. Show strong ability to apply and integrate knowledge and theory relating to the basic foundation knowledge of bioinorganic chemistry. Show strong ability to analyze novel problems and critical use of data and experimental results to draw appropriate and insightful conclusions relating to the basic principles and knowledge of bioinorganic chemistry. Demonstrate highly effective basic techniques, especially in the characterization of inorganic active site and overall metallo-biomolecules. B Demonstrate substantial command of knowledge and understanding of essential facts, concepts, principles, and theories relating to the basic foundation knowledge of bioinorganic chemistry, especially those related to hard-soft acid-base theory; chelation; structure and bonding of metals in biological systems; thermodynamic and kinetic aspects of metal ions in biological processes and their relevance to metal homeostasis; metal-based drugs. Show evidence to apply and integrate knowledge and theory relating to the basic foundation knowledge of bioinorganic chemistry. Show evidence to analyze novel problems and correct use of data and experimental results to draw appropriate conclusions relating to the basic principles and knowledge of bioinorganic chemistry. Demonstrate effective basic techniques, especially in the characterization of inorganic active site and overall metallo-biomolecules. C Demonstrate general but incomplete command of knowledge and understanding of essential facts, concepts, principles, and theories relating to the basic foundation knowledge of bioinorganic chemistry, especially those related to hard-soft acid-base theory; chelation; structure and bonding of metals in biological systems; thermodynamic and kinetic aspects of metal ions in biological processes and their relevance to metal homeostasis; metal-based drugs. Show evidence of some abilities to apply and integrate knowledge and theory relating to the basic foundation knowledge of bioinorganic chemistry. Show ability to analyze problems to most familiar situations and mostly correct but erroneous use of data and experimental results to draw appropriate conclusions relating to the basic principles and knowledge of bioinorganic chemistry. Demonstrate moderately effective basic techniques, especially in the characterization of inorganic active site and overall metallo-biomolecules. D Demonstrate partial but limited command of knowledge and understanding of essential facts, concepts, principles, and theories relating to the basic foundation knowledge of bioinorganic chemistry, especially those related to hard-soft acid-base theory; chelation; structure and bonding of metals in biological systems; thermodynamic and kinetic aspects of metal ions in biological processes and their relevance to metal homeostasis; metal-based drugs. Show evidence of limited abilities to apply and integrate knowledge and theory relating to the basic foundation knowledge of bioinorganic chemistry. Show limited ability to analyze problems to most familiar situations and mostly correct but erroneous use of data and experimental results to draw appropriate conclusions relating to the basic principles and knowledge of bioinorganic chemistry. Demonstrate partially effective basic techniques, especially in the characterization of inorganic active site and overall metallo-biomolecules. Fail Demonstrate little or no evidence of command of knowledge and understanding of essential facts, concepts, principles, and theories relating to the basic foundation knowledge of bioinorganic chemistry, especially those related to hard-soft acid-base theory; chelation; structure and bonding of metals in biological systems; thermodynamic and kinetic aspects of metal ions in biological processes and their relevance to metal homeostasis; metal-based drugs. Show little or no evidence of abilities to apply and integrate knowledge and theory relating to the basic foundation knowledge of bioinorganic chemistry. Show little or no ability to analyze problems to most familiar situations and erroneous use of data and experimental results to draw appropriate conclusions relating to the basic principles and knowledge of bioinorganic chemistry. Demonstrate minimally effective basic techniques, especially in the characterization of inorganic active site and overall metallo-biomolecules.
Communication-intensive Course	N
Course Type	Lecture-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Lectures 36.0 Tutorials including literature survey & presentation 12.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments 25.0 1,2,3,4 Examination 50.0 1,2,3,4 Test (quiz/test) 25.0 1,2,3,4
Required/recommended reading and online materials	Lippard, S. J. and Berg, J. M. Principles of Bioinorganic Chemistry (University Science Books; Mill Valley, CA, 1994 Bertini, I.; Gray, H. B.; Stiefel, E. I.; Valentine, J. S., editors. Biological Inorganic Chemistry: Structure and Reactivity, University Science Books, 2007 Metals and Life, Moore C., RSC Publishing, 2010. Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life, Kaim W. & Schwederski B., John Wiley & Sons, 2013.
Course Website	NIL
Additional Course Information

CHEM3441 Organic chemistry II (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	300
Course Co-ordinator	Prof Z X Huang (1st sem); Prof X Y Li (2nd sem), Chemistry < huangzx@hku.hk; xiaoyuli@hku.hk >
Teachers Involved	(Prof X D Li,Chemistry) (Prof X Y Li,Chemistry) (Prof Z X Huang,Chemistry)
Course Objectives	As a continuation from CHEM2441 Organic Chemistry I, this course aims to provide a solid foundation of organic chemistry together with CHEM2441.  It focuses primarily on the basic principles to understand the structure and reactivity of organic molecules, with examples illustrating the role of organic chemistry in daily life and industry.
Course Contents & Topics	Chemistry of common organic functional groups: ketones and aldehydes; carboxylic acids and their derivatives; amines; aromatic compounds. Principles of organic synthesis.  Detailed considerations of reaction mechanisms. Spectroscopic tools (UV-Vis, IR, NMR, and MS) for characterization and identification of organic compounds.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 draw correct structural representations of organic molecules CLO 2 understand the basic principles of structure and reactivity of organic molecules CLO 3 determine structures of organic compounds based on spectroscopic data CLO 4 write reasonable mechanisms for transformations of common functional groups (alcohols, ethers, carbonyl compounds, aldehydes, ketones, carboxylic acids, acyl halides, anhydrides, esters, amides, nitriles, and amines) CLO 5 appreciate the importance of organic chemistry in daily life CLO 6 devise synthetic pathways to organic compounds using functional group chemistry
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM2441 [Remarks: CHEM3441 has been changed to lecture-based course from semester 2, 2015-16.  For Chemistry students who admitted in 2014-15 or before, they must enroll also CHEM3443 for enrolling CHEM3441 (new version without lab component) to meet the Chemistry Major requirements.]
Course Status with Related Major/Minor /Professional Core	2025 Major in Biochemistry ( Disciplinary Elective ) 2025 Major in Chemistry ( Core/Compulsory ) 2025 Major in Chemistry (Intensive) ( Core/Compulsory ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Biochemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Core/Compulsory ) 2024 Major in Chemistry (Intensive) ( Core/Compulsory ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Biochemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Core/Compulsory ) 2023 Major in Chemistry (Intensive) ( Core/Compulsory ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Biochemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Core/Compulsory ) 2022 Major in Chemistry (Intensive) ( Core/Compulsory ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Biochemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Core/Compulsory ) 2021 Major in Chemistry (Intensive) ( Core/Compulsory ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Biochemistry < PLO 1,2,3,4,5 > 2025 Major in Chemistry < PLO 1,2,3,4,5 > 2025 Major in Chemistry (Intensive) < PLO 1,2,3,4,5 > 2024 Major in Biochemistry < PLO 1,2,3,4,5 > 2024 Major in Chemistry < PLO 1,2,3,4,5 > 2024 Major in Chemistry (Intensive) < PLO 1,2,3,4,5 > 2023 Major in Biochemistry < PLO 1,2,3,4,5 > 2023 Major in Chemistry < PLO 1,2,3,4,5 > 2023 Major in Chemistry (Intensive) < PLO 1,2,3,4,5 > 2022 Major in Biochemistry < PLO 1,2,3,4,5 > 2022 Major in Chemistry < PLO 1,2,3,4,5 > 2022 Major in Chemistry (Intensive) < PLO 1,2,3,4,5 > 2021 Major in Biochemistry < PLO 1,2,3,4,5 > 2021 Major in Chemistry < PLO 1,2,3,4,5 > 2021 Major in Chemistry (Intensive) < PLO 1,2,3,4,5 >
Offer in 2025 - 2026	Y        1st sem    2nd sem	Examination	Dec    May
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough mastery at an advanced level of extensive knowledge and skills required for attaining all the course learning outcomes. Show strong analytical and critical abilities and logical thinking, with evidence of original thought, and ability to apply knowledge to a wide range of complex, familiar and unfamiliar situations. B Demonstrate substantial command of a broad range of knowledge and skills required for attaining at least most of the course learning outcomes. Show evidence of analytical and critical abilities and logical thinking, and ability to apply knowledge to familiar and some unfamiliar situations. C Demonstrate general but incomplete command of knowledge and skills required for attaining most of the course learning outcomes. Show evidence of some analytical and critical abilities and logical thinking, and ability to apply knowledge to most familiar situations. D Demonstrate partial but limited command of knowledge and skills required for attaining some of the course learning outcomes. Show evidence of some coherent and logical thinking, but with limited analytical and critical abilities. Show limited ability to apply knowledge to solve problems. Fail Demonstrate little or no evidence of command of knowledge and skills required for attaining the course learning outcomes. Lack of analytical and critical abilities, logical and coherent thinking. Show very little or no ability to apply knowledge to solve problems.
Communication-intensive Course	N
Course Type	Lecture-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Lectures 36.0 Tutorials 12.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments (assignment x 2) 20.0 1,2,3,4,5,6 Examination 50.0 1,2,3,4,5,6 Test (mid-term test x 2) 30.0 1,2,3,4,5,6
Required/recommended reading and online materials	"Organic Chemistry", by Paula Y. Bruice, 2016, 8th Edition, Pearson, with e-text and Mastering Chemistry.  Chapters 14-20.
Course Website	NIL
Additional Course Information

CHEM3442 Organic chemistry of biomolecules (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	50
Course Co-ordinator	Prof P H Toy, Chemistry < phtoy@hku.hk >
Teachers Involved	(Prof P H Toy,Chemistry) (Prof Y X Li,Chemistry)
Course Objectives	The major objective of this course is to give the students an understanding and appreciation of the role of organic chemistry in biology and biochemistry.
Course Contents & Topics	The chemistry of organic molecule groups such as carbohydrates, amino acids, peptides, coenzymes, nucleotides and lipids will discussed.  Enzyme catalysis, cofactors and inhibitors will also be presented.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 have a basic understanding of biologically important organic molecules CLO 2 have a basic understanding of enzyme catalysis CLO 3 appreciate how organic chemistry plays an important role in biology and biochemistry
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM2442 or CHEM3441
Course Status with Related Major/Minor /Professional Core	2U000C00 Course not offered under any Major/Minor/Professional core 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping
Offer in 2025 - 2026	Y        1st sem	Examination	Dec
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough mastery at an advanced level of extensive biomolecule organic chemistry knowledge, and skills required for attaining all the course learning outcomes. Show strong analytical and critical abilities and logical thinking, with evidence of original thought, and ability to apply knowledge to a wide range of complex, familiar and unfamiliar problems. Apply highly effective organizational and presentational skills. B Demonstrate substantial command of biomolecule organic chemistry with a broad range of knowledge, and skills required for attaining at least most of the course learning outcomes. Show evidence of analytical and critical abilities and logical thinking, and ability to apply knowledge to familiar and some unfamiliar problems. Apply effective organizational and presentational skills. C Demonstrate general but incomplete command of biomolecule organic chemistry knowledge, and skills required for attaining most of the course learning outcomes. Show evidence of some analytical and critical abilities and logical thinking, and ability to apply knowledge to most familiar problems. Apply moderately effective organizational and presentational skills. D Demonstrate partial but limited command of biomolecule organic chemistry knowledge, and skills required for attaining some of the course learning outcomes. Show evidence of some coherent and logical thinking, but with limited analytical and critical abilities. Show limited ability to apply knowledge to solve problems. Apply limited or barely effective organizational and presentational skills. Fail Demonstrate little or no evidence of command of biomolecule organic chemistry knowledge, and skills required for attaining the course learning outcomes. Lack of analytical and critical abilities, logical and coherent thinking. Show very little or no ability to apply knowledge to solve problems. Organization and presentational skills are minimally effective or ineffective.
Communication-intensive Course	N
Course Type	Lecture-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Lectures 36.0 Tutorials 12.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Examination 50.0 1,2,3 Presentation 10.0 1,2,3 Test (2-mid term tests) 40.0 1,2,3
Required/recommended reading and online materials	Bruice, P.Y.; Organic Chemistry (Pearson, 2017, 8th edition), Chapters 20-26.
Course Website
Additional Course Information

CHEM3443 Organic chemistry laboratory (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	90
Course Co-ordinator	Dr A M Y Yuen, Chemistry < maiyan@hku.hk >
Teachers Involved	(Dr A M Y Yuen,Chemistry) (Prof J Z Liu,Chemistry)
Course Objectives	To provide students with intensive hands-on training of experimental chemistry techniques on organic reactions; and the opportunity to develop analytical and critical thinking skills through scientific investigations in organic chemistry experiments. The course focuses on the practical aspects of a variety of organic reactions, including and multistep syntheses. Chromatographic, instrumental, and spectroscopic techniques are also discussed to give a holistic training of experimental organic chemistry.
Course Contents & Topics	The course will include the following laboratory skills and practices: laboratory safety practice; preparation, purification, and characterization of organic compounds; gas and liquid chromatography; ultraviolet-visible spectrophotometry; infrared spectroscopy; NMR spectroscopy and melting point determination
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 demonstrate a good practice of laboratory safety and exercise proper procedures for safe handling and usage of chemicals CLO 2 carry out, record and analyze the results of chemical experiments CLO 3 apply modern instrumentation techniques to characterize organic compounds and draw conclusions from the results CLO 4 communicate the results of their work to others CLO 5 demonstrate problem-solving skills, critical thinking and analytical reasoning
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM2441; and pass in CHEM3441, or already enrolled in this course; NOT for students who have passed CHEM3441A in semester 1, 2015-16, or CHEM3441 in or before 2014-2015 (for students admitted in 2014-15 or before) Pass in CHEM2441 or CHEM2442 or CHEM2443; and Pass in CHEM3441 or CHEM3442, or already enrolled in any of these two courses (for students admitted in 2015-16 or thereafter)
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry ( Core/Compulsory ) 2025 Major in Chemistry (Intensive) ( Core/Compulsory ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Core/Compulsory ) 2024 Major in Chemistry (Intensive) ( Core/Compulsory ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Core/Compulsory ) 2023 Major in Chemistry (Intensive) ( Core/Compulsory ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Core/Compulsory ) 2022 Major in Chemistry (Intensive) ( Core/Compulsory ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Core/Compulsory ) 2021 Major in Chemistry (Intensive) ( Core/Compulsory ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry < PLO 1,2,3,4,5 > 2025 Major in Chemistry (Intensive) < PLO 1,2,3,4,5 > 2024 Major in Chemistry < PLO 1,2,3,4,5 > 2024 Major in Chemistry (Intensive) < PLO 1,2,3,4,5 > 2023 Major in Chemistry < PLO 1,2,3,4,5 > 2023 Major in Chemistry (Intensive) < PLO 1,2,3,4,5 > 2022 Major in Chemistry < PLO 1,2,3,4,5 > 2022 Major in Chemistry (Intensive) < PLO 1,2,3,4,5 > 2021 Major in Chemistry < PLO 1,2,3,4,5 > 2021 Major in Chemistry (Intensive) < PLO 1,2,3,4,5 >
Offer in 2025 - 2026	Y        1st sem    2nd sem	Examination	Dec    May
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate extensive knowledge and thorough command of concepts and principles which are required for attaining all the course learning outcomes. Show strong analytical and critical abilities and logical thinking, with ability to apply knowledge to a wide range of complex, familiar and unfamiliar situations. Competently conduct experiment with efficient lab skills and techniques. Critically appraise data to draw appropriate and insightful conclusions. Apply highly effective organizational and presentational skills. B Demonstrate substantial command of a broad range of knowledge and skills required for attaining at least most of the course learning outcomes. Show substantial grasp and mastery of the subject knowledge. Demonstrate evidence of analytical and critical abilities and logical thinking, and ability to apply knowledge to familiar and some unfamiliar situations. Show effective lab skills and techniques and critical analysis of experimental data. Apply effective organizational and presentational skills. C Demonstrate general but incomplete command of knowledge and skills required for attaining most of the course learning outcomes. Show general but incomplete grasp of the subject knowledge. Demonstrate evidence of some analytical and critical abilities and logical thinking, and ability to apply knowledge to most familiar situations. Show moderately effective lab skills and techniques. Demonstrated some ability to analyze experimental data critically. Apply moderately effective organizational and presentational skills. D Demonstrate partial but limited command of knowledge and skills required for attaining course learning outcomes. Ability to recall some of factual information of the subject. Show a partial comprehension of basic concepts and principles and weak ability to apply them. Demonstrate evidence of some coherent and logical thinking, but with limited analytical and critical abilities. Demonstrate partially effective lab skills and techniques. Apply limited or barely effective organizational and presentational skills. Fail Demonstrate little or no evidence of command of knowledge and skills required for attaining the course learning outcomes. Show evidence of little or no grasp of the knowledge and understanding of the subject. Lack of analytical and critical abilities, logical and coherent thinking. Show very little or no ability to apply knowledge to solve problems. Demonstrate minimally effective or ineffective lab skills and techniques. Organization and presentational skills are minimally effective or ineffective.
Communication-intensive Course	N
Course Type	Lecture with laboratory component course
Course Teaching & Learning Activities	Activities Details No. of Hours Laboratory 12 x 4-hr lab sessions 48.0 Tutorials 12.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Examination (20% practical exam and 30% 2-hr written exam) 50.0 1,2,3,4,5 Laboratory reports (Include Lab Quiz 15%, Lab Report and Notebook 25% and Lab Performance 10%) 50.0 1,2,3,4,5
Required/recommended reading and online materials	John W. Lehman: Operational Organic Chemistry - A Problem-Solving Approach to the Laboratory Course (Pearson, latest edition)
Course Website	NIL
Additional Course Information	Laboratory classes are mandatory.  Students must complete ALL experiments and laboratory reports to pass this course.

CHEM3445 Integrated laboratory (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	20
Course Co-ordinator	Prof J He, Chemistry < jianhe@hku.hk >
Teachers Involved	(Prof J He,Chemistry) (Prof K Okuro,Chemistry)
Course Objectives	This course aims to provide students with experience using techniques employed in synthetic organic and organometallic chemistry. This advanced synthesis course covering a variety of synthetic methods, including vacuum and inert atmosphere techniques to prepare organic and organometallic compounds; methods for separation of mixtures and isolation of products by use of column and thin-layer chromatography, sublimation and extraction techniques. Experiments on characterization and identification by chemical and spectroscopic methods form an important part of the course. The use of the chemical literature in molecular design and synthesis planning is also included.
Course Contents & Topics	The course will include the following laboratory skills and practices: laboratory safety practice; molecular design, synthesis planning, experimental set up, purification, and characterization of organic compounds using modern instrumentation techniques.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 Demonstrate a good practice of laboratory safety and exercise proper procedures for safe handling and usage of chemicals CLO 2 Demonstrate proficiency in synthetic chemical laboratory techniques CLO 3 Apply modern instrumentation techniques to characterize organic compounds and draw conclusions from the results CLO 4 Analyze the influence of chemical structure on the physical and chemical properties of organic molecules CLO 5 Demonstrate problem-solving skills, critical thinking and analytical reasoning
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM3443 or already enrolled in this course
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry (Intensive) ( Core/Compulsory ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry (Intensive) ( Core/Compulsory ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry (Intensive) ( Core/Compulsory ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry (Intensive) ( Core/Compulsory ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry (Intensive) ( Core/Compulsory ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry (Intensive) < PLO 1,3,4,5 > 2024 Major in Chemistry (Intensive) < PLO 1,3,4,5 > 2023 Major in Chemistry (Intensive) < PLO 1,3,4,5 > 2022 Major in Chemistry (Intensive) < PLO 1,3,4,5 > 2021 Major in Chemistry (Intensive) < PLO 1,3,4,5 >
Offer in 2025 - 2026	Y        Summer	Examination	No Exam
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate extensive knowledge and thorough command of concepts and principles which are required for attaining all the course learning outcomes. Show strong analytical and critical abilities and logical thinking, with ability to apply knowledge to a wide range of complex, familiar and unfamiliar situations. Competently conduct experiment with efficient lab skills and techniques. Critically appraise data to draw appropriate and insightful conclusions. Apply highly effective organizational and presentational skills. B Demonstrate substantial command of a broad range of knowledge and skills required for attaining at least most of the course learning outcomes. Show substantial grasp and mastery of the subject knowledge. Demonstrate evidence of analytical and critical abilities and logical thinking, and ability to apply knowledge to familiar and some unfamiliar situations. Show effective lab skills and techniques and critical analysis of experimental data. Apply effective organizational and presentational skills. C Demonstrate general but incomplete command of knowledge and skills required for attaining most of the course learning outcomes. Show general but incomplete grasp of the subject knowledge. Demonstrate evidence of some analytical and critical abilities and logical thinking, and ability to apply knowledge to most familiar situations. Show moderately effective lab skills and techniques. Demonstrated some ability to analyze experimental data critically. Apply moderately effective organizational and presentational skills. D Demonstrate partial but limited command of knowledge and skills required for attaining course learning outcomes. Ability to recall some of factual information of the subject. Show a partial comprehension of basic concepts and principles and weak ability to apply them. Demonstrate evidence of some coherent and logical thinking, but with limited analytical and critical abilities. Demonstrate partially effective lab skills and techniques. Apply limited or barely effective organizational and presentational skills. Fail Demonstrate little or no evidence of command of knowledge and skills required for attaining the course learning outcomes. Show evidence of little or no grasp of the knowledge and understanding of the subject. Lack of analytical and critical abilities, logical and coherent thinking. Show very little or no ability to apply knowledge to solve problems. Demonstrate minimally effective or ineffective lab skills and techniques. Organization and presentational skills are minimally effective or ineffective.
Communication-intensive Course	N
Course Type	Lecture with laboratory component course
Course Teaching & Learning Activities	Activities Details No. of Hours Laboratory 48.0 Tutorials 12.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Laboratory reports (Practical Examination 25%; Lab report 10%; Lab performance 10%) 45.0 1,2,3,4,5 Presentation 20.0 3,4,5 Test (test/quiz) 35.0 1,2,3,4,5
Required/recommended reading and online materials	John W. Lehman: Operational Organic Chemistry - A Problem-Solving Approach to the Laboratory Course (Pearson, latest edition)
Course Website
Additional Course Information	Laboratory classes are mandatory.  Students must complete ALL experiments and laboratory reports to pass this course.

CHEM3541 Physical chemistry: Introduction to quantum chemistry (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	100
Course Co-ordinator	Prof G H Chen, Chemistry < ghc@yangtze.hku.hk >
Teachers Involved	(Prof G H Chen,Chemistry)
Course Objectives	The course presents fundamental principles and topics on quantum chemistry in order to provide a soiled foundation for students intending to further their studies in chemistry.
Course Contents & Topics	Elementary quantum mechanics: Historical development, Postulates of quantum mechanics, Principles of quantum mechanics, Theory of angular momentum, Heisenberg uncertainty principle. Applications to simple systems: particle in a box, harmonic oscillator, rigid rotator; Atomic structure: Hydrogen and many electron atoms. Molecular structure and chemical bonds. Approximation methods: variational method, Hartree-Fock method, valence bond theory, and perturbation theory.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 understand and use the terminology and nomenclature in quantum chemistry and topics discussed in the course CLO 2 demonstrate knowledge and understanding of basic concepts in quantum mechanics, atomic and molecular structure CLO 3 understand elementary numerical procedures and the basic relationships of quantum mechanics and molecular systems CLO 4 hands-on experience of the application of Hartree-Fock method to molecules
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM2541
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry ( Core/Compulsory ) 2025 Major in Chemistry (Intensive) ( Core/Compulsory ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Core/Compulsory ) 2024 Major in Chemistry (Intensive) ( Core/Compulsory ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Core/Compulsory ) 2023 Major in Chemistry (Intensive) ( Core/Compulsory ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Core/Compulsory ) 2022 Major in Chemistry (Intensive) ( Core/Compulsory ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Core/Compulsory ) 2021 Major in Chemistry (Intensive) ( Core/Compulsory ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry < PLO 2,4,5 > 2025 Major in Chemistry (Intensive) < PLO 2,4,5 > 2024 Major in Chemistry < PLO 2,4,5 > 2024 Major in Chemistry (Intensive) < PLO 2,4,5 > 2023 Major in Chemistry < PLO 2,4,5 > 2023 Major in Chemistry (Intensive) < PLO 2,4,5 > 2022 Major in Chemistry < PLO 2,4,5 > 2022 Major in Chemistry (Intensive) < PLO 2,4,5 > 2021 Major in Chemistry < PLO 2,4,5 > 2021 Major in Chemistry (Intensive) < PLO 2,4,5 >
Offer in 2025 - 2026	Y        1st sem	Examination	Dec
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough mastery at an advanced level of extensive knowledge and skills required for attaining all the course learning outcomes. Show strong analytical and critical abilities and logical thinking, with thorough grasp of the subject, and ability to apply knowledge to a wide range of complex, familiar and unfamiliar situations. Apply highly effective lab skills and techniques. Critical use of data and results to draw appropriate and insightful conclusions. B Demonstrate substantial command of a broad range of knowledge and skills required for attaining at least most of the course learning outcomes. Show evidence of analytical and critical abilities and logical thinking, and substantial grasp of the subject, ability to apply knowledge to familiar and some unfamiliar situations. Apply effective lab skills and techniques. Correct use of data of results to draw appropriate conclusions. C Demonstrate general but incomplete command of knowledge and skills required for attaining most of the course learning outcomes. Show evidence of some analytical and critical abilities and logical thinking, and general but incomplete grasp of the subject, ability to apply knowledge to most familiar situations. Apply moderately effective lab skills and techniques. Mostly correct but some erroneous use of data and results to draw appropriate conclusions. D Demonstrate partial but limited command of knowledge and skills required for attaining some of the course learning outcomes. Show evidence of some coherent and logical thinking, but with limited analytical and critical abilities. Show partial but limited grasp of the subject, retention of some relevant information of the subject, ability to apply knowledge to solve problems. Apply partially effective lab skills and techniques. Limited ability to use data and results to draw appropriate conclusions. Fail Demonstrate little or no evidence of command of knowledge and skills required for attaining the course learning outcomes. Lack of analytical and critical abilities, logical and coherent thinking. Show little or no grasp of the knowledge and understanding of the subject, very little or no ability to apply knowledge to solve problems. Apply minimally effective or ineffective lab skills and techniques. Misuse of data and results and/or unable to draw appropriate conclusions.
Communication-intensive Course	N
Course Type	Lecture with laboratory component course
Course Teaching & Learning Activities	Activities Details No. of Hours Laboratory 24.0 Lectures 24.0 Tutorials 6.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Examination 50.0 1,2,3 Laboratory reports (experiment & lab report) 20.0 1,2,3,4 Test (test/quiz) 30.0 1,2,3
Required/recommended reading and online materials	D. A. McQuarrie: Quantum Chemistry (2nd Edition, 2007) I. N. Levin: Quantum Chemistry (5th Edition, 2008)
Course Website	NIL
Additional Course Information	Laboratory classes are mandatory.  Students must complete ALL experiments and laboratory reports to pass this course.

CHEM3542 Physical chemistry: statistical thermodynamics and kinetics theory (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	50
Course Co-ordinator	Prof J Yang, Chemistry < juny@hku.hk >
Teachers Involved	(Prof J Yang,Chemistry)
Course Objectives	The course presents fundamental principles and topics on statistical thermodynamics and kinetic theory in order to provide a solid foundation for students intending to further their studies in physical chemistry and related fields.
Course Contents & Topics	Principles of Statistical Thermodynamics - Statistical model and state distribution for thermodynamics - Statistical entropy - Ensembles and partition functions: microcanonical and canonical - Systems of independent molecules: ideal gas - Molecular degrees of freedom: translation, rotation, vibration, and electronic - Ideal gas mixture: chemical equilibrium - Calculation of free energies in gaseous reaction Chemical equilibrium and kinetics theory - Rate theory: collision theory, transition state theory and applications
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 understand and use the terminology and nomenclature in statistical thermodynamics and topics discussed in the course CLO 2 demonstrate knowledge and understanding of basic concepts in statistical thermodynamics CLO 3 understand correlation between macroscopic observables and microscopic statistical model systems
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM2541 and CHEM3541
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry (Intensive) ( Core/Compulsory ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry (Intensive) ( Core/Compulsory ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry (Intensive) ( Core/Compulsory ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry (Intensive) ( Core/Compulsory ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry (Intensive) ( Core/Compulsory ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry (Intensive) < PLO 1,2,3,4,5 > 2024 Major in Chemistry (Intensive) < PLO 1,2,3,4,5 > 2023 Major in Chemistry (Intensive) < PLO 1,2,3,4,5 > 2022 Major in Chemistry (Intensive) < PLO 1,2,3,4,5 > 2021 Major in Chemistry (Intensive) < PLO 1,2,3,4,5 >
Offer in 2025 - 2026	Y        2nd sem	Examination	May
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Thorough mastery at an advanced level of extensive knowledge of statistical thermodynamics and reaction dynamics. Demonstrate evidence of strong analytical / critical abilities and logical thinking. Can apply the knowledge to practical questions in Physical Chemistry. B Substantial command of knowledge of statistical thermodynamics and reaction dynamics. Demonstrate evidence of analytical / critical abilities and logical thinking. Understand the scope of Physical Chemistry questions that can be applied with the knowledge. C General but incomplete command of knowledge of statistical thermodynamics and reaction dynamics. Demonstrate evidence of analytical thinking. Can apply the knowledge to familiar situations. D Partial but limited command of knowledge of knowledge of statistical thermodynamics and reaction dynamics. Demonstrate limited evidence of analytical thinking. Understand the question to be solved with knowledge. Fail Little or no evidence of command of knowledge of statistical thermodynamics and reaction dynamics.
Communication-intensive Course	N
Course Type	Lecture with laboratory component course
Course Teaching & Learning Activities	Activities Details No. of Hours Laboratory 24.0 Lectures 24.0 Tutorials 8.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments 50.0 1,2,3 Examination 50.0 1,2,3
Required/recommended reading and online materials	P. Atkins: Physical Chemistry (10th edition) K.A. Dill & S. Bromberg: Molecular driving forces: statistical thermodynamics in biology, chemistry, physics and nanoscicence (2nd edition) B. Widom: Statistical Mechanics: a concise introduction to chemists L. Nash: Elements of statistical thermodynamics (2nd edition)
Course Website	Nil
Additional Course Information	There are three mandatory homework assignments. Laboratory classes are mandatory.  Students must complete ALL experiments and laboratory reports to pass this course.

CHEM3999 Directed studies in chemistry (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	---
Course Co-ordinator	Prof S K Lee, Chemistry < skchem@hku.hk >
Teachers Involved	(Various teachers in the Department,Chemistry)
Course Objectives	This course is designed for third year students who would like to take an early experience on research.  It offers students an opportunity to carry out small scale chemical projects by themselves.
Course Contents & Topics	Students interested in taking this course should contact their prospective supervisors in May to determine the contents and the nature of their project in the coming academic year.  Prior approval from both the prospective supervisor and the course coordinator is required.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 understand the terminology and nomenclature associated with the small scale chemical project they worked on in the course CLO 2 demonstrate knowledge and understanding of basic concepts involved in their chemical project CLO 3 understand the relationships of the their particular chemical project to the wider area of chemistry
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in at least 24 credits of advanced level disciplinary core/elective chemistry courses (CHEM3XXX or CHEM4XXX) in the Chemistry Major including a pass in CHEM2341 or CHEM2441 or CHEM2442 or CHEM2541. This capstone course is for Chemistry Major/ Chemistry Major (Intensive) students only. This course is designed for third year students who would like to take an early experience on research. The earliest that a student is allowed to take this capstone course is their year 3 study.
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry ( Disciplinary Elective ) 2025 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry < PLO 1,2,3,4,5,6 > 2025 Major in Chemistry (Intensive) < PLO 1,2,3,4,5,6 > 2024 Major in Chemistry < PLO 1,2,3,4,5,6 > 2024 Major in Chemistry (Intensive) < PLO 1,2,3,4,5,6 > 2023 Major in Chemistry < PLO 1,2,3,4,5,6 > 2023 Major in Chemistry (Intensive) < PLO 1,2,3,4,5,6 > 2022 Major in Chemistry < PLO 1,2,3,4,5,6 > 2022 Major in Chemistry (Intensive) < PLO 1,2,3,4,5,6 > 2021 Major in Chemistry < PLO 1,2,3,4,5,6 > 2021 Major in Chemistry (Intensive) < PLO 1,2,3,4,5,6 >
Offer in 2025 - 2026	Y        1st sem    2nd sem	Examination	No Exam
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Show an extensive comprehension of the subject. Demonstrate very able analytical and critical thought with presence of some originality. Illuminating utilization and critical analysis / evaluation of information acquired from a wide range of high quality sources. Critical employment of data and results to synthesize appropriate and illuminating conclusions. Demonstrate integration of a wide range of appropriate theories, principles, data and methods. Employ very effective organizational and presentational skills. [Work of A+ should demonstrate substantial additional work beyond that is required in wider areas relevant to the topic.] B Show a substantial comprehension of the subject. Demonstrate able analytical and critical thinking with use of relevant information from sources. Demonstrate ability to compose meaningful comparisons between different secondary interpretations. Correct utilization of data and results to form appropriate conclusions. Compose general integration of theories, principles, data and methods. Perform effective organizational and presentational skills. C Show a general but incomplete comprehension of the subject. Presence of some analytical and critical thinking with use of relevant information from sources. Demonstrate ability to compose comparisons between different interpretations. Mainly correct but some incorrect utilization of data and results to form appropriate conclusions. Demonstrate some partial integration of theories, principles, data and methods. Perform moderately effective organizational and presentational skills. D Show a partial but limited comprehension, with knowledge of some relevant information, of the subject. Presence of some coherent and logical thinking, but with limited analytical and critical abilities. Show utilization and reference of several sources, but mostly via summary instead of by analysis and comparison. Limited ability to employ data and results to form appropriate conclusions. Demonstrate limited integration of theories, principles, data and methods. Perform limited or marginally effective organizational and presentational skills. Fail Show little or no comprehension of the subject. Evidence of little or lack of analytical and critical abilities, logical and coherent thinking. Limited employment of secondary sources and no critical comparison of them. Incorrectly utilize data and results and/or unable to form appropriate conclusions. Demonstrate little or no integration of theories, principles, data and methods. Organization and presentational skills are of very limited use or ineffective.
Communication-intensive Course	N
Course Type	Project-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Reading / Self study discussion & meetings to be arranged by the student and the supervisor 120.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Dissertation Written report 30.0 1,2,3 Oral presentation 20.0 1,2,3 Research report Research (experimental and/or computational study in a research group) 50.0 1,2,3
Required/recommended reading and online materials	Recommended reading material will be assigned depending on the project.
Course Website	NIL
Additional Course Information	Exceptional academic strength of the students is required for taking this course. The course may involve Laboratory component as Course Teaching & Learning Activities.

CHEM4142 Symmetry, group theory and applications (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	60
Course Co-ordinator	Prof E C M Tse, Chemistry < ecmtse@hku.hk >
Teachers Involved	(Dr K K H Ng,Chemistry) (Prof E C M Tse,Chemistry)
Course Objectives	To introduce the concepts of symmetry and group theory and to apply them in solving chemical problems.  This course also provides an introductory treatment of bonding theories, inorganic electronic and vibrational spectroscopy.  This course is essential for students who wish to take advanced courses in inorganic chemistry and all types of spectroscopy.
Course Contents & Topics	Symmetry elements and symmetry operations; symmetry point groups; reducible and irreducible representations; character tables; direct products; symmetry-adapted linear combinations; projection operators; hybrid orbitals; molecular orbital theory for organic, inorganic and organometallic systems; selected applications in electronic and vibrational spectroscopy.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 understand the basic principles and concepts of symmetry and group theory and to apply them in solving chemical problems CLO 2 demonstrate knowledge and understanding in the use of character tables and projection operator techniques CLO 3 demonstrate knowledge and understanding of bonding theories involving hybrid orbitals and molecular orbitals for organic, inorganic and organometallic systems CLO 4 demonstrate knowledge and understanding in the application of symmetry and group theory in electronic and vibrational spectroscopy
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM3341
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry ( Disciplinary Elective ) 2025 Major in Chemistry (Intensive) ( Core/Compulsory ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry (Intensive) ( Core/Compulsory ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry (Intensive) ( Core/Compulsory ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry (Intensive) ( Core/Compulsory ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry (Intensive) ( Core/Compulsory ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry < PLO 2,3,4 > 2025 Major in Chemistry (Intensive) < PLO 2,3,4 > 2024 Major in Chemistry < PLO 2,3,4 > 2024 Major in Chemistry (Intensive) < PLO 2,3,4 > 2023 Major in Chemistry < PLO 2,3,4 > 2023 Major in Chemistry (Intensive) < PLO 2,3,4 > 2022 Major in Chemistry < PLO 2,3,4 > 2022 Major in Chemistry (Intensive) < PLO 2,3,4 > 2021 Major in Chemistry < PLO 2,3,4 > 2021 Major in Chemistry (Intensive) < PLO 2,3,4 >
Offer in 2025 - 2026	Y        1st sem	Examination	Dec
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough knowledge and understanding of essential facts, concepts, principles, and theories relating to symmetry and group theory and their applications in solving chemical problems, especially those related to symmetry elements and symmetry operations; symmetry point groups; reducible and irreducible representations; character tables; direct products; symmetry-adapted linear combinations; projection operators; treatment of bonding theories including hybrid orbitals and molecular orbitals for organic, inorganic and orgametallic systems; and applications in electronic and vibrational spectroscopy. Show strong ability to apply and integrate knowledge and theory relating to the basic principles and concepts of symmetry and group theory and their applications in bonding, and electronic and vibrational spectroscopy. Show strong ability to analyze novel problems and critical use of data and experimental results to draw appropriate and insightful conclusions relating to the principles and applications of symmetry and group theory. B Demonstrate substantial command of knowledge and understanding of essential facts, concepts, principles, and theories relating to symmetry and group theory and their applications in solving chemical problems, especially those related to symmetry elements and symmetry operations; symmetry point groups; reducible and irreducible representations; character tables; direct products; symmetry-adapted linear combinations; projection operators; treatment of bonding theories including hybrid orbitals and molecular orbitals for organic, inorganic and orgametallic systems; and applications in electronic and vibrational spectroscopy. Show evidence to apply and integrate knowledge and theory relating to the basic principles and concepts of symmetry and group theory and their applications in bonding, and electronic and vibrational spectroscopy. Show evidence to analyze novel problems and correct use of data and experimental results to draw appropriate conclusions relating to the principles and applications of symmetry and group theory. C Demonstrate general but incomplete command of knowledge and understanding of essential facts, concepts, principles, and theories relating to symmetry and group theory and their applications in solving chemical problems, especially those related to symmetry elements and symmetry operations; symmetry point groups; reducible and irreducible representations; character tables; direct products; symmetry-adapted linear combinations; projection operators; treatment of bonding theories including hybrid orbitals and molecular orbitals for organic, inorganic and orgametallic systems; and applications in electronic and vibrational spectroscopy. Show evidence of some abilities to apply and integrate knowledge and theory relating to the basic principles and concepts of symmetry and group theory and their applications in bonding, and electronic and vibrational spectroscopy. Show ability to analyze problems to most familiar situations and mostly correct but erroneous use of data and experimental results to draw appropriate conclusions relating to the principles and applications of symmetry and group theory. D Demonstrate partial but limited command of knowledge and understanding of essential facts, concepts, principles, and theories relating to symmetry and group theory and their applications in solving chemical problems, especially those related to symmetry elements and symmetry operations; symmetry point groups; reducible and irreducible representations; character tables; direct products; symmetry-adapted linear combinations; projection operators; treatment of bonding theories including hybrid orbitals and molecular orbitals for organic, inorganic and orgametallic systems; and applications in electronic and vibrational spectroscopy. Show evidence of limited abilities to apply and integrate knowledge and theory relating to the basic principles and concepts of symmetry and group theory and their applications in bonding, and electronic and vibrational spectroscopy. Show limited ability to analyze problems to most familiar situations and mostly correct but erroneous use of data and experimental results to draw appropriate conclusions relating to the principles and applications of symmetry and group theory. Fail Demonstrate little or no evidence of command of knowledge and understanding of essential facts, concepts, principles, and theories relating to symmetry and group theory and their applications in solving chemical problems, especially those related to symmetry elements and symmetry operations; symmetry point groups; reducible and irreducible representations; character tables; direct products; symmetry-adapted linear combinations; projection operators; treatment of bonding theories including hybrid orbitals and molecular orbitals for organic, inorganic and orgametallic systems; and applications in electronic and vibrational spectroscopy. Show little or no evidence of abilities to apply and integrate knowledge and theory relating to the basic principles and concepts of symmetry and group theory and their applications in bonding, and electronic and vibrational spectroscopy. Show little or no ability to analyze problems to most familiar situations and erroneous use of data and experimental results to draw appropriate conclusions relating to the principles and applications of symmetry and group theory.
Communication-intensive Course	N
Course Type	Lecture-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Lectures 36.0 Tutorials or discussion 12.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments 25.0 1,2,3,4 Examination 50.0 1,2,3,4 Test (test/project) 25.0 1,2,3,4
Required/recommended reading and online materials	F.A. Cotton: Chemical Applications of Group Theory (Wiley, 3rd ed., 1990)
Course Website	NIL
Additional Course Information	This course is also offered to RPg students, and the course code for RPg students is CHEM6116.

   <<< This course is not offered in 2025-2026. Course details are subject to change. >>>

CHEM4143 Interfacial science and technology (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	50
Course Co-ordinator	Prof G K Y Chan, Chemistry < hrsccky@hku.hk >
Teachers Involved	(Prof G K Y Chan,Chemistry) (Visiting Professor,Chemistry)
Course Objectives	To understand the science and technology of interfacial phenomena and processes often appeared in high value added products and modern technologies.
Course Contents & Topics	Physics and Chemistry of Interfaces: coatings and surfactants, colloids and interfaces, wetting, microemulsion, thin films, nanomaterials, porous materials.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 understand interfacial phenomena and their origin from molecular details CLO 2 solve problems in interfacial science and technology by applying knowledge of general chemistry, thermodynamics, and kinetics CLO 3 be familiarized with technologies that require application of interfacial science, including nanomaterials, nanotechnology, detergency, composite polymers, and porosimetry
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM3143 or CHEM3541 or CHEM3542
Course Status with Related Major/Minor /Professional Core	2U000C00 Course not offered under any Major/Minor/Professional core 2023 Major in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2023 Major in Chemistry < PLO 1,2,3,5,6 > 2023 Major in Chemistry (Intensive) < PLO 1,2,3,5,6 > 2022 Major in Chemistry < PLO 1,2,3,5,6 > 2022 Major in Chemistry (Intensive) < PLO 1,2,3,5,6 > 2021 Major in Chemistry < PLO 1,2,3,5,6 > 2021 Major in Chemistry (Intensive) < PLO 1,2,3,5,6 >
Offer in 2025 - 2026	N	Examination
Offer in 2026 - 2027	N
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough knowledge of interfacial science and technology, and mastery of skills required for attaining all of the course learning outcomes. Show strong analytical and critical abilities and logical thinking, with evidence of original thought, and ability to apply knowledge to solve problems in a wide range of complex, familiar and unfamiliar situations. Critical use of data and sourcing of references. Apply highly effective organizational and presentational skills. B Demonstrate substantial knowledge of interfacial science and technology and command of skills required for attaining at least most of the course learning outcomes. Show evidence of analytical and critical abilities and logical thinking, and ability to apply knowledge to solve problems in familiar and some unfamiliar situations. Correct use of data and sourcing of references. Apply effective organizational and presentational skills. C Demonstrate general but incomplete knowledge of interfacial science and technology and command of skills required for attaining most of the course learning outcomes. Show evidence of some analytical and critical abilities and logical thinking, and ability to apply knowledge solve problems to most familiar situations. Mostly correct but some erroneous use of data and references. Apply moderately effective organizational and presentational skills. D Demonstrate partial but limited knowledge of interfacial science and technology and command of skills required for attaining some of the course learning outcomes. Show evidence of some coherent and logical thinking, but with limited analytical and critical abilities. Show limited ability to apply knowledge to solve problems. Limited ability to use data and source references. Apply limited or barely effective organizational and presentational skills. Fail Demonstrate little or no evidence of knowledge of interfacial science and technology, and command of skills required for attaining the course learning outcomes. Lack of analytical and critical abilities, logical and coherent thinking. Show very little or no ability to apply knowledge to solve problems. Misuse of data and references. Organization and presentational skills are minimally effective or ineffective.
Communication-intensive Course	N
Course Type	Lecture-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Lectures 36.0 Tutorials or discussion 12.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments 25.0 1,2,3 Examination 50.0 1,2,3 Test 25.0 1,2,3
Required/recommended reading and online materials	Barnes and Gentle: Interfacial Science
Course Website	NIL
Additional Course Information	This course is offered every other year.

CHEM4144 Advanced materials (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	30
Course Co-ordinator	Prof E C M Tse, Chemistry < ecmtse@hku.hk >
Teachers Involved	(Prof E C M Tse,Chemistry) (Prof K Okuro,Chemistry)
Course Objectives	This course is a continuation from Introduction to Materials Chemistry. It provides a more comprehensive overview on materials chemistry and application of materials in advanced technology. The most recent development in materials chemistry will also be discussed.
Course Contents & Topics	This course covers both hard and soft materials in the macroscale and nanoscale regimes for renewable energy, catalytic devices, sustainable resourcification, wearable biosensors, nanoelectronics, membrane technology, and other specialty applications. Advanced materials synthesis and characterization methods are also introduced.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 describe the preparation methods of 2D and 3D materials CLO 2 identify morphology-performance relationship in nanomaterials CLO 3 demonstrate knowledge in advanced materials characterization techniques CLO 4 understand the working principles of materials for real-life applications
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM3143
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry ( Disciplinary Elective ) 2025 Major in Chemistry (Intensive) ( Core/Compulsory ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry (Intensive) ( Core/Compulsory ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry (Intensive) ( Core/Compulsory ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry (Intensive) ( Core/Compulsory ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry (Intensive) ( Core/Compulsory ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry < PLO 1,2,3,4 > 2025 Major in Chemistry (Intensive) < PLO 1,2,3,4 > 2024 Major in Chemistry < PLO 1,2,3,4 > 2024 Major in Chemistry (Intensive) < PLO 1,2,3,4 > 2023 Major in Chemistry < PLO 1,2,3,4 > 2023 Major in Chemistry (Intensive) < PLO 1,2,3,4 > 2022 Major in Chemistry < PLO 1,2,3,4 > 2022 Major in Chemistry (Intensive) < PLO 1,2,3,4 > 2021 Major in Chemistry < PLO 1,2,3,4 > 2021 Major in Chemistry (Intensive) < PLO 1,2,3,4 >
Offer in 2025 - 2026	Y        2nd sem	Examination	May
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough knowledge and understanding of essential facts, concepts, principles, and theories relating to frontier approach in polymer synthesis, properties, application, and characterization of materials for advanced technology. Show strong ability to apply and integrate knowledge and theory relating to the synthesis and applications of advanced materials. Show strong ability to analyze novel problems and critical use of data and experimental results to draw appropriate and insightful conclusions relating to advanced materials synthesis and their properties. B Demonstrate substantial command of knowledge and understanding of essential facts, concepts, principles, and theories relating to frontier approach in polymer synthesis, properties, application, and characterization of materials for advanced technology. Show evidence to apply and integrate knowledge and theory relating to the synthesis and applications of advanced materials. Show evidence to analyze novel problems and correct use of data and experimental results to draw appropriate conclusions relating to advanced materials synthesis and their properties. C Demonstrate general but incomplete command of knowledge and understanding of essential facts, concepts, principles, and theories relating to frontier approach in polymer synthesis, properties, application, and characterization of materials for advanced technology. Show evidence of some abilities to apply and integrate knowledge and theory relating to the synthesis and applications of advanced materials. Show ability to analyze problems to most familiar situations and mostly correct but erroneous use of data and experimental results to draw appropriate conclusions relating to advanced materials synthesis and their properties. D Demonstrate partial but limited command of knowledge and understanding of essential facts, concepts, principles, and theories relating to frontier approach in polymer synthesis, properties, application, and characterization of materials for advanced technology. Show evidence of limited abilities to apply and integrate knowledge and theory relating to the synthesis and applications of advanced materials. Show limited ability to analyze problems to most familiar situations and mostly correct but erroneous use of data and experimental results to draw appropriate conclusions relating to advanced materials synthesis and their properties. Fail Demonstrate little or no evidence of command of knowledge and understanding of essential facts, concepts, principles, and theories relating to frontier approach in polymer synthesis, properties, application, and characterization of materials for advanced technology. Show little or no evidence of abilities to apply and integrate knowledge and theory relating to the synthesis and applications of advanced materials. Show little or no ability to analyze problems to most familiar situations and erroneous use of data and experimental results to draw appropriate conclusions relating to advanced materials synthesis and their properties.
Communication-intensive Course	N
Course Type	Lecture-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Lectures 36.0 Tutorials or discussion 12.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments Literature (Article / Patent) 30.0 1,2,3,4 Examination Exam / Presentation 50.0 1,2,3,4 Test Test / Project 20.0 1,2,3,4
Required/recommended reading and online materials	Specialist references will be given throughout the course.
Course Website	NIL
Additional Course Information	NIL

CHEM4145 Medicinal chemistry (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	40
Course Co-ordinator	Prof Y Li, Chemistry < yingli0e@hku.hk >
Teachers Involved	(Prof P H Toy,Chemistry) (Prof X C Li,Chemistry) (Prof Y Li,Chemistry)
Course Objectives	This course covers the chemical principles of drug design and drug action and uses as an introduction to research in areas of bioorganic chemistry, bioinorganic chemistry, medicinal chemistry, pharmaceutical chemistry, and biotechnology.
Course Contents & Topics	- Drug discovery, design, and development: lead discovery, pharmacophore, structure-activity relationships (SAR), computer-aided drug design, combinatorial chemistry and high-throughput drug screening - Drug-receptor interactions - Proteins (and enzymes) and nucleic acids as drug targets - Metals in medicine - DNA-Drug interactions - Drug metabolism and prodrugs and drug delivery
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 demonstrate knowledge of drug discovery, design and development CLO 2 understand drug-biomolecule interactions where appropriate CLO 3 gain appropriate knowledge of drug metabolism and drug delivery
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM3441 or CHEM3442; and Not for students who have passed in BPHM3133, or already enrolled in this course.
Course Status with Related Major/Minor /Professional Core	2025 Major in Biochemistry ( Disciplinary Elective ) 2025 Major in Chemistry ( Disciplinary Elective ) 2025 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Biochemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Biochemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Biochemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Biochemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Biochemistry < PLO 1,2,3,4,5 > 2025 Major in Chemistry < PLO 2,3,4 > 2025 Major in Chemistry (Intensive) < PLO 2,3,4 > 2024 Major in Biochemistry < PLO 1,2,3,4,5 > 2024 Major in Chemistry < PLO 2,3,4 > 2024 Major in Chemistry (Intensive) < PLO 2,3,4 > 2023 Major in Biochemistry < PLO 1,2,3,4,5 > 2023 Major in Chemistry < PLO 2,3,4 > 2023 Major in Chemistry (Intensive) < PLO 2,3,4 > 2022 Major in Biochemistry < PLO 1,2,3,4,5 > 2022 Major in Chemistry < PLO 2,3,4 > 2022 Major in Chemistry (Intensive) < PLO 2,3,4 > 2021 Major in Biochemistry < PLO 1,2,3,4,5 > 2021 Major in Chemistry < PLO 2,3,4 > 2021 Major in Chemistry (Intensive) < PLO 2,3,4 >
Offer in 2025 - 2026	Y        2nd sem	Examination	May
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough knowledge and understanding of essential facts, concepts, principles, and theories relating to the basic foundation knowledge of medicinal chemistry, especially those related to drug discovery, design and development; drug targets; drug lead optimization; structure activity relationship; pharmacokinetics; drug delivery and its relevance to toxicity. Show strong ability to apply and integrate knowledge and theory relating to the basic foundation knowledge of medicinal chemistry. Show strong ability to analyze novel problems and critical use of data and experimental results to draw appropriate and insightful conclusions relating to the basic principles and knowledge of medicinal chemistry. Demonstrate highly effective basic techniques for medicinal chemistry, especially in drug discovery and metabolism. B Demonstrate substantial command of knowledge and understanding of essential facts, concepts, principles, and theories relating to the basic foundation knowledge of medicinal chemistry; especially those related to drug discovery; design and development; drug targets; drug lead optimization; structure activity relationship; pharmacokinetics; drug delivery and its relevance to toxicity. Show evidence to apply and integrate knowledge and theory relating to the basic foundation knowledge of medicinal chemistry. Show evidence to analyze novel problems and correct use of data and experimental results to draw appropriate conclusions relating to the basic principles and knowledge of medicinal chemistry. Demonstrate effective basic techniques for medicinal chemistry, especially in drug discovery and metabolism. C Demonstrate general but incomplete command of knowledge and understanding of essential facts, concepts, principles, and theories relating to the basic foundation knowledge of medicinal chemistry; especially those related to drug discovery; design and development; drug targets; drug lead optimization; structure activity relationship; pharmacokinetics; drug delivery and its relevance to toxicity. Show evidence of some abilities to apply and integrate knowledge and theory relating to the basic foundation knowledge of medicinal chemistry. Show ability to analyze problems to most familiar situations and mostly correct but erroneous use of data and experimental results to draw appropriate conclusions relating to the basic principles and knowledge of medicinal chemistry. Demonstrate moderately effective basic techniques, basic techniques for medicinal chemistry, especially in drug discovery and metabolism. D Demonstrate partial but limited command of knowledge and understanding of essential facts, concepts, principles, and theories relating to the basic foundation knowledge of medicinal chemistry; especially those related to drug discovery; design and development; drug targets; drug lead optimization; structure activity relationship; pharmacokinetics; drug delivery and its relevance to toxicity. Show evidence of limited abilities to apply and integrate knowledge and theory relating to the basic foundation knowledge of medicinal chemistry. Show limited ability to analyze problems to most familiar situations and mostly correct but erroneous use of data and experimental results to draw appropriate conclusions relating to the basic principles and knowledge of medicinal chemistry. Demonstrate partially effective basic techniques for medicinal chemistry, especially in drug discovery and metabolism. Fail Demonstrate little or no evidence of command of knowledge and understanding of essential facts, concepts, principles, and theories relating to the basic foundation knowledge of medicinal chemistry; especially those related to drug discovery; design and development; drug targets; drug lead optimization; structure activity relationship; pharmacokinetics; drug delivery and its relevance to toxicity. Show little or no evidence of abilities to apply and integrate knowledge and theory relating to the basic foundation knowledge of medicinal chemistry. Show little or no ability to analyze problems to most familiar situations and erroneous use of data and experimental results to draw appropriate conclusions relating to the basic principles and knowledge of medicinal chemistry. Demonstrate minimally effective basic techniques for medicinal chemistry, especially in drug discovery and metabolism.
Communication-intensive Course	N
Course Type	Lecture-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Lectures 36.0 Tutorials or discussion 12.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments 30.0 1,2,3 Examination 50.0 1,2,3 Test (mid-term test) 20.0 1,2,3
Required/recommended reading and online materials	An Introduction to Medicinal Chemistry (3/e), G.L. Patrick, Oxford University Press, 2005 Medicinal Chemistry- An Introduction, G. Thomas, John Wiley, 2000 D. Wang, S.J. Lippard (2004) Nat. Rev. Drug Dis., Cellular processing of platinum anticancer drugs, 4, 307-320
Course Website	NIL
Additional Course Information	This course is also offered to RPg students, and the course code for RPg students is CHEM6113.

CHEM4147 Supramolecular chemistry (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	40
Course Co-ordinator	Prof K Okuro, Chemistry < okuro@hku.hk >
Teachers Involved	(Prof K Okuro,Chemistry) (Prof Y F Wang,Chemistry)
Course Objectives	Supramolecular chemistry concerns the chemistry beyond that of molecules. This course aims at introducing students to concepts and techniques in supramolecular chemistry, demonstrating how molecular assembly and supramolecular structures leads to functions and properties, and their relevance to material and biological science.
Course Contents & Topics	Basic concepts in molecular recognition and self-assembly; non-covalent interactions and common supramolecular building blocks; methods in supramolecular chemistry. Selected topics in modern supramolecular chemistry, such as macrocycles and cages, molecular capsule and container molecules, synthetic receptors, interlocked structures, supramolecular polymers and supramolecular chemistry of biomolecules and biomaterials, will also be discussed.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 Understand important principles and concepts in supramolecular chemistry CLO 2 Demonstrate knowledge and understanding in the nature of non-covalent interactions and to apply these concepts in the design and explanation of the structures, properties and functions of different supramolecular systems CLO 3 Interpret and analyse physical characterization data of supramolecular systems and extract relevant chemical information to explain the properties of the supramolecular systems
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM3341 and CHEM3441
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry ( Disciplinary Elective ) 2025 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry < PLO 1,2,3,5 > 2025 Major in Chemistry (Intensive) < PLO 1,2,3,5 > 2024 Major in Chemistry < PLO 1,2,3,5 > 2024 Major in Chemistry (Intensive) < PLO 1,2,3,5 > 2023 Major in Chemistry < PLO 1,2,3,5 > 2023 Major in Chemistry (Intensive) < PLO 1,2,3,5 > 2022 Major in Chemistry < PLO 1,2,3,5 > 2022 Major in Chemistry (Intensive) < PLO 1,2,3,5 > 2021 Major in Chemistry < PLO 1,2,3,5 > 2021 Major in Chemistry (Intensive) < PLO 1,2,3,5 >
Offer in 2025 - 2026	Y        2nd sem	Examination	May
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough knowledge and understanding of essential facts, concepts and principles in supramolecular chemistry, especially those relating to non-covalent interactions, molecular recognition and self-assembly. Show strong ability to apply and integrate knowledge in supramolecular chemistry in explaining the formation and properties of, and in designing different supramolecular systems. Show strong ability to analyse and interpret experimental data to draw appropriate conclusions relating to the advanced principles and properties of supramolecular systems. B Demonstrate substantial knowledge and understanding of essential facts, concepts and principles in supramolecular chemistry, especially those relating to non-covalent interactions, molecular recognition and self-assembly. Show evidence to apply and integrate knowledge in supramolecular chemistry in explaining the formation and properties of, and in designing different supramolecular systems. Show evidence to analyse and interpret experimental data to draw appropriate conclusions relating to the advanced principles and properties of supramolecular systems. C Demonstrate general but incomplete amount of knowledge and understanding of essential facts, concepts and principles in supramolecular chemistry, especially those relating to non-covalent interactions, molecular recognition and self-assembly. Show some ability to apply and integrate knowledge in supramolecular chemistry in explaining the formation and properties of, and in designing different supramolecular systems. Show some ability to analyse and interpret experimental data to draw appropriate conclusions relating to the advanced principles and properties of supramolecular systems. D Demonstrate partial but incomplete command of knowledge and understanding of essential facts, concepts and principles in supramolecular chemistry, especially those relating to non-covalent interactions, molecular recognition and self-assembly. Show evidence of limited ability to apply and integrate knowledge in supramolecular chemistry in explaining the formation and properties of, and in designing different supramolecular systems. Show limited ability to analyse and interpret experimental data to draw appropriate conclusions relating to the advanced principles and properties of supramolecular systems. Fail Demonstrate little or no evidence of command of knowledge and understanding of essential facts, concepts and principles in supramolecular chemistry, especially those relating to non-covalent interactions, molecular recognition and self-assembly. Show little or no ability to apply and integrate knowledge in supramolecular chemistry in explaining the formation and properties of, and in designing different supramolecular systems. Show little or no ability to analyse and interpret experimental data to draw appropriate conclusions relating to the advanced principles and properties of supramolecular systems.
Communication-intensive Course	N
Course Type	Lecture-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Lectures 36.0 Tutorials 12.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments 15.0 1,2,3 Examination 50.0 1,2,3 Presentation 15.0 1,2,3 Test 20.0 1,2,3
Required/recommended reading and online materials	Supramolecular Chemistry by Jonathan W. Steed and Jerry L. Atwood, John Wiley & Sons, Ltd., 2nd Edition, 2009 Modern Physical Organic Chemistry by Eric V. Anslyn and Dennis A. Dougherty, University Science Books, 2006 References to specialist texts and other published materials will be made throughout the course.
Course Website
Additional Course Information

CHEM4148 Frontiers in Modern Chemical Science (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	60
Course Co-ordinator	Prof X D Li, Chemistry < xiangli@hku.hk >
Teachers Involved	(Prof A M Li,Chemistry) (Prof J Y Tang,Chemistry) (Prof X D Li,Chemistry)
Course Objectives	Modern chemistry is thought to be the "central science" as it plays a critical role in related biological, physical, medical, and engineering disciplines. This course aims to introduce students to the newest concepts and technological breakthroughs in chemical sciences. Throughout the course, students will be introduced to how the interplay among molecules, materials, and interfaces leads to unprecedented functionalities that contribute to innovations in biology and medicine, smart materials, and sustainable energy schemes.
Course Contents & Topics	Current topics focus on the interdisciplinary area of chemistry with biology, and material sciences.  Covered topics include chemical genetics, epigenetics and proteomics; chemical biology for drug discovery and development; stimuli-responsive nanomaterials; autonomous macromolecular motion; future power landscape; renewable energy conversion and utilization. Examples in protein posttranslational modifications, active colloidal, thermoelectric materials, molecular machines, advanced rechargeable batteries, and next-generation fuel cells and electrolysers will be discussed.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 understand important principles and topical trends in chemical sciences CLO 2 demonstrate understanding of future directions in biomedical chemistry, nanomatertials, and energy sciences and applying this knowledge in comparing and contrasting various emergent technologies CLO 3 interpret and analyse recent published research data in the field of chemistry and extract relevant chemical information to explain the observed properties and phenomena associated to the chemical systems
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM3341 and CHEM3441.
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry ( Disciplinary Elective ) 2025 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry < PLO 1,2,3,5 > 2025 Major in Chemistry (Intensive) < PLO 1,2,3,5 > 2024 Major in Chemistry < PLO 1,2,3,5 > 2024 Major in Chemistry (Intensive) < PLO 1,2,3,5 > 2023 Major in Chemistry < PLO 1,2,3,5 > 2023 Major in Chemistry (Intensive) < PLO 1,2,3,5 > 2022 Major in Chemistry < PLO 1,2,3,5 > 2022 Major in Chemistry (Intensive) < PLO 1,2,3,5 > 2021 Major in Chemistry < PLO 1,2,3,5 > 2021 Major in Chemistry (Intensive) < PLO 1,2,3,5 >
Offer in 2025 - 2026	Y        2nd sem	Examination	No Exam
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough knowledge and understanding of essential facts, concepts and principles in chemical sciences, especially those relating to biomedical chemistry, nanomaterials, and energy sciences. Show strong ability to apply and integrate knowledge in chemical sciences in explaining the formation and properties of chemical species and in designing different chemical systems. Show strong ability in the literature review, research proposal writing, and oral presentation for frontier topics in chemical sciences. B Demonstrate substantial knowledge and understanding of essential facts, concepts and principles in chemical sciences, especially those relating to biomedical chemistry, nanomaterials, and energy sciences. Show evidence to apply and integrate knowledge in chemical sciences in explaining the formation and properties of chemical species and in designing different chemical systems. Show good ability in the literature review, research proposal writing, and oral presentation for frontier topics in chemical sciences. C Demonstrate general but incomplete amount of knowledge and understanding of essential facts, concepts and principles in chemical sciences, especially those relating to biomedical chemistry, nanomaterials, and energy sciences. Show some ability to apply and integrate knowledge in chemical sciences in explaining the formation and properties of chemical species and in designing different chemical systems. Show some ability in the literature review, research proposal writing, and oral presentation for frontier topics in chemical sciences. D Demonstrate partial but incomplete command of knowledge and understanding of essential facts, concepts and principles in chemical sciences, especially those relating to biomedical chemistry, nanomaterials, and energy sciences. Show evidence of limited ability to apply and integrate knowledge in chemical sciences in explaining the formation and properties of chemical species and in designing different chemical systems. Show limited ability in the literature review, research proposal writing, and oral presentation for frontier topics in chemical sciences. Fail Demonstrate little or no evidence of command of knowledge and understanding of essential facts, concepts and principles in chemical sciences, especially those relating to biomedical chemistry, nanomaterials, and energy sciences. Show little or no ability to apply and integrate knowledge in chemical sciences in explaining the formation and properties of chemical species and in designing different chemical systems. Show little or no ability in the literature review, research proposal writing, and oral presentation for frontier topics in chemical sciences.
Communication-intensive Course	N
Course Type	Lecture-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Lectures 36.0 Tutorials 12.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments 30.0 1,2,3 Essay (Proposal) 35.0 1,2,3 Presentation 35.0 1,2,3
Required/recommended reading and online materials	References to specialized texts and other published materials will be made throughout the course.
Course Website
Additional Course Information	This course is also offered to RPg students, and the course code for RPg students is CHEM6118.

CHEM4241 Modern chemical instrumentation and applications (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	50
Course Co-ordinator	Prof I K Chu, Chemistry < ivankchu@hku.hk >
Teachers Involved	(Prof H B Jiang,Chemistry) (Prof I K Chu,Chemistry)
Course Objectives	The aim of the course is to provide an understanding of modern instrumentation, covering both fundamental principles and practical aspects of instrument design.  The course will be of particular benefit to those pursuing a higher research degree or a career in technical sales/service.
Course Contents & Topics	Biological Mass spectrometry: Liquid Chromatography-Tandem Mass Spectrometry for Proteomics & Metabolomics. Microscopy and analysis with light and electron beams: instrumentation and applications in physical and life sciences.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 explain the principles of the modern mass spectrometric methods for proteins and metabolites identification and quantification CLO 2 explain how proteins are identified and sequenced experimentally and how data is generated in proteomics experiments CLO 3 use the database searching techniques and software tools to analyze high-throughput proteomics data CLO 4 apply LC/MS/MS method for target quantitative analysis of small molecules CLO 5 explain the principles of optical microscopy and electron microscopy and their capabilities CLO 6 describe the basic experimental set up and the properties of the basic components of the instruments used in the laboratory classes
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM3241
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry ( Disciplinary Elective ) 2025 Major in Chemistry (Intensive) ( Core/Compulsory ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry (Intensive) ( Core/Compulsory ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry (Intensive) ( Core/Compulsory ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry (Intensive) ( Core/Compulsory ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry (Intensive) ( Core/Compulsory ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry < PLO 2,4,5 > 2025 Major in Chemistry (Intensive) < PLO 2,4,5 > 2024 Major in Chemistry < PLO 2,4,5 > 2024 Major in Chemistry (Intensive) < PLO 2,4,5 > 2023 Major in Chemistry < PLO 2,4,5 > 2023 Major in Chemistry (Intensive) < PLO 2,4,5 > 2022 Major in Chemistry < PLO 2,4,5 > 2022 Major in Chemistry (Intensive) < PLO 2,4,5 > 2021 Major in Chemistry < PLO 2,4,5 > 2021 Major in Chemistry (Intensive) < PLO 2,4,5 >
Offer in 2025 - 2026	Y        1st sem	Examination	Dec
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough knowledge and understanding of essential facts, concepts, principles and theories relating to the modern chemical instrumentations and applications. Show strong ability to apply and integrate knowledge and theory, and strong ability to analyze problems related to fundamental principles and practical aspects of instrument design. B Demonstrate substantial command of knowledge and understanding of essential facts, concepts, principles and theories relating to the modern chemical instrumentations and applications. Show evidence to apply and integrate knowledge and theory, and ability to analyze problems related to fundamental principles and practical aspects of instrument design. C Demonstrate general but incomplete command of knowledge and understanding of essential facts, concepts, principles and theories relating to the modern chemical instrumentations and applications. Show evidence of some abilities to apply and integrate knowledge and theory, and to analyze problems to most familiar situations to fundamental principles and practical aspects of instrument design. D Demonstrate partial but limited command of knowledge and understanding of essential facts, concepts, principles and theories relating to the modern chemical instrumentations and applications. Show evidence of limited abilities to apply and integrate knowledge and theory, and limited ability to analyze problems to most familiar situations related to fundamental principles and practical aspects of instrument design. Fail Demonstrate little or no evidence of command of knowledge and understanding of essential facts, concepts, principles and theories relating to the modern chemical instrumentations and applications. Show little or no evidence of abilities to apply and integrate knowledge and theory, and little or no ability to analyze problems to most familiar situations related to fundamental principles and practical aspects of instrument design.
Communication-intensive Course	N
Course Type	Lecture with laboratory component course
Course Teaching & Learning Activities	Activities Details No. of Hours Laboratory 16.0 Lectures 24.0 Tutorials 12.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments 10.0 1,2,3,4,5,6 Examination 50.0 1,2,3,4,5,6 Laboratory reports (lab performance, reports) 25.0 6 Test 15.0 1,2,3,4,5,6
Required/recommended reading and online materials	Chhabil Dass: Fundamentals of contemporary mass spectrometry (Wiley-Interscience) D.A. Skoog, F.K. Holler, S.R. Crouch: Principles of Instrumental Analysis (Thomson, latest edition) Reference to published material will be made throughout the course.
Course Website	NIL
Additional Course Information	Laboratory classes are mandatory.  Students must complete ALL experiments and laboratory reports to pass this course. This course is also offered to RPg students, and the course code for RPg students is CHEM6117.

CHEM4242 Advanced analytical chemistry (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	50
Course Co-ordinator	Prof H B Jiang, Chemistry < hbjiang@hku.hk >
Teachers Involved	(Prof H B Jiang,Chemistry)
Course Objectives	This course focuses on the basic principle, practice and methodology in chemical and biochemical analysis. The course emphasizes on the integration of analytical concepts and technologies to solve practical analytical and bioanalytical problems. This course will be particularly useful for students who plan to pursue their career related to analytical and bioanalytical chemistry.
Course Contents & Topics	Sample preparation and enrichment techniques for biomedical, pharmaceutical and forensic chemical analysis; Theoretical background and practical techniques of biological sample analysis; Advanced instrumental techniques and analytical methods; Recent developments in microscopy and imaging techniques; Introduction to spatial omics technologies.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 apply statistical methods to assess analytical measurement data quality and interpret their significance, validate analytical methods and results CLO 2 demonstrate understanding on the working principle of different analytical techniques and recognize their advantages and limitations CLO 3 integrate different analytical techniques to solve analytical and bioanalytical problems
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in  CHEM3241 or CHEM3242
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry ( Disciplinary Elective ) 2025 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry < PLO 2,3,4,5 > 2025 Major in Chemistry (Intensive) < PLO 2,3,4,5 > 2024 Major in Chemistry < PLO 2,3,4,5 > 2024 Major in Chemistry (Intensive) < PLO 2,3,4,5 > 2023 Major in Chemistry < PLO 2,3,4,5 > 2023 Major in Chemistry (Intensive) < PLO 2,3,4,5 > 2022 Major in Chemistry < PLO 2,3,4,5 > 2022 Major in Chemistry (Intensive) < PLO 2,3,4,5 > 2021 Major in Chemistry < PLO 2,3,4,5 > 2021 Major in Chemistry (Intensive) < PLO 2,3,4,5 >
Offer in 2025 - 2026	Y        2nd sem	Examination	May
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough mastery at an advanced level of extensive knowledge and skills required for attaining all the course learning outcomes. Show strong analytical and critical abilities, logical thinking and capability to apply knowledge learnt to solve a wide range of complex issues and problems related to chemical analysis. Apply highly effective organization and presentation skills as shown in class work. B Demonstrate a substantial command of a broad range of knowledge and skills required for attaining at least most of the course learning outcomes. Show evidence of analytical and critical abilities, logical thinking, and capability to apply knowledge learnt to solve a wide range of complex issues and problems related to chemical analysis. Apply effective organization and presentation skills as shown in class work. C Demonstrate a general command of knowledge and skills required for attaining most of the course learning outcomes. Show evidence of analytical and critical abilities, logical thinking, and ability to apply knowledge learnt to solve a wide range of complex issues and problems related to chemical analysis. Apply effective organization and presentation skills as shown in class work. D Demonstrate a partial but limited command of knowledge and skills required for attaining some of the course learning outcomes in Food and Water Analysis. Show evidence of some coherent and logical thinking, but with limited analytical and critical abilities. Show limited ability to apply knowledge to solve problems related to chemical analysis. Apply limited or barely effective organization and presentation skill as shown in class work. Fail Demonstrate little or no evidence for the command of knowledge and skills required for attaining the course learning outcomes. Lack of analytical and critical abilities, logical and coherent thinking. Show very little or no ability to apply knowledge to solve problems related to chemical analysis. Organization and presentation skills are minimally effective or ineffective as shown in class work.
Communication-intensive Course	N
Course Type	Lecture with laboratory component course
Course Teaching & Learning Activities	Activities Details No. of Hours Laboratory 24.0 Lectures 24.0 Tutorials 6.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments 20.0 1,2,3 Examination 50.0 1,2,3 Laboratory reports (experiment & lab report) 15.0 1,2 Presentation 15.0 1,2,3
Required/recommended reading and online materials	D.A. Skoog, D.M. West, F.J. Holler, S.R. Crouch: Fundamentals of Analytical Chemistry (Cengage Learning, latest edition) A. Manz, P. S. Dittrich, N. Pamme, D. Iossifidis: Bioanalytical Chemistry (Imperial College Press, latest edition) References to specialist texts and other published materials will be made throughout the course.
Course Website	NIL
Additional Course Information	Laboratory classes are mandatory.  Students must complete ALL experiments and laboratory reports to pass this course.

CHEM4341 Advanced inorganic chemistry (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	50
Course Co-ordinator	Prof C M Che, Chemistry < cmche@hku.hk >
Teachers Involved	(Prof C M Che,Chemistry) (Prof H Z Sun,Chemistry) (Prof V W W Yam,Chemistry)
Course Objectives	This course is a continuation from Intermediate Inorganic Chemistry, giving further and more detailed treatment to topics in Inorganic Chemistry and new areas of interest. Problem based learning on selected advance topics will be introduced in the later part of the course. This course also aims to prepare students for graduate work.
Course Contents & Topics	Selected advanced topics of current interest. Examples include metal-metal bonds and metal-ligand multiple bonds, inorganic and supramolecular photochemistry, lanthanide chemistry, bio-inorganic and medicinal chemistry, and activation of small molecules by metal complexes.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 understand the principles and concepts of inorganic and supramolecular photochemistry CLO 2 understand the electronic structure and bondings of novel metal-metal and metal-ligand multiple bonded metal complexes CLO 3 understand and realize the activation of small molecules by transition metal complexes and realize the importance of such activation in chemical catalysis of global interest, green chemistry and energy saving reactions CLO 4 understand the role of metal complexes in bio-inorganic and medicinal chemistry
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM3341
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry ( Disciplinary Elective ) 2025 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry < PLO 2,3 > 2025 Major in Chemistry (Intensive) < PLO 2,3 > 2024 Major in Chemistry < PLO 2,3 > 2024 Major in Chemistry (Intensive) < PLO 2,3 > 2023 Major in Chemistry < PLO 2,3 > 2023 Major in Chemistry (Intensive) < PLO 2,3 > 2022 Major in Chemistry < PLO 2,3 > 2022 Major in Chemistry (Intensive) < PLO 2,3 > 2021 Major in Chemistry < PLO 2,3 > 2021 Major in Chemistry (Intensive) < PLO 2,3 >
Offer in 2025 - 2026	Y        1st sem	Examination	Dec
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough knowledge and understanding of essential facts, concepts, principles and theories relating to the frontiers in inorganic chemistry. Show strong ability to apply and integrate knowledge and theory, and strong ability to analyze novel problems in inorganic chemistry. Apply highly effective organizational and presentational skills. B Demonstrate substantial command of knowledge and understanding of essential facts, concepts, principles and theories relating to the more advanced knowledge in inorganic chemistry. Show evidence to apply and integrate knowledge and theory, and ability to analyze novel problems of inorganic chemistry. Apply effective organizational and presentational skills. C Demonstrate general but incomplete command of knowledge and understanding of essential facts, concepts, principles and theories relating to the more advanced knowledge in inorganic chemistry. Show evidence of some abilities to apply and integrate knowledge and theory, and to analyze problems to most familiar situations in inorganic chemistry. Apply moderately effective organizational and presentational skills. D Demonstrate partial but limited command of knowledge and understanding of essential facts, concepts, principles and theories relating to the more advanced knowledge in inorganic chemistry. Show evidence of limited abilities to apply and integrate knowledge and theory, and limited ability to analyze problems to most familiar situations in inorganic chemistry. Demonstrate partially effective organizational and presentational skills. Fail Demonstrate little or no evidence of command of knowledge and understanding of essential facts, concepts, principles and theories relating to the more advanced knowledge in inorganic chemistry. Show little or no evidence of abilities to apply and integrate knowledge and theory, and little or no ability to analyze problems to most familiar situations in inorganic chemistry. Demonstrate minimally effective organizational and presentational skills.
Communication-intensive Course	N
Course Type	Lecture-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Lectures 36.0 Tutorials including literature survey & presentation 12.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments 25.0 1,2,3,4 Examination 50.0 1,2,3,4 Test (quiz/ test) 25.0 1,2,3,4
Required/recommended reading and online materials	F.A. Cotton, G. Wilkinson, Hurillo and Bochmann: Advance Inorganic Chemistry (Wiley, 1999, 6th ed.) References to specialist texts and other published materials will be made throughout the course.
Course Website	NIL
Additional Course Information	(Students are strongly recommended to take CHEM4142 Symmetry, group theory and applications if they wish to take this course.) This course is also offered to RPg students, and the course code for RPg students is CHEM6115.

CHEM4342 Organometallic chemistry (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	32
Course Co-ordinator	Prof J He, Chemistry < jianhe@hku.hk >
Teachers Involved	(Prof J He,Chemistry) (Prof J Z Liu,Chemistry)
Course Objectives	To give further, more detailed, treatment to organometallic chemistry mentioned in CHEM3341 Inorganic Chemistry II.  The course also aims to introduce and familiarize students with advanced laboratory techniques, and to prepare students for graduate work in inorganic and organometallic chemistry.
Course Contents & Topics	Lectures: Main group and transition metal organometallics.  Transition metal cluster chemistry. Bonding, structure and reactivities of organometallics.  Application of organometallics in organic synthesis and catalysis. Laboratory: To introduce and familiarize students with advanced laboratory techniques which include the synthesis and manipulation of air- and moisture- sensitive compounds, and their characterization by various spectroscopic methods.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 understand the advanced principles and concepts in organometallic chemistry CLO 2 demonstrate knowledge and understanding in the bonding, structure and reactivities of main group and transition metal organometallics, especially in transition metal clusters, metal alkyls, metal alkylidenes and metal alkylidynes CLO 3 demonstrate knowledge and understanding in the application of organometallics in organic synthesis, polymerization and catalysis CLO 4 demonstrate ability in advanced laboratory techniques including the synthesis and manipulation of air- and moisture- sensitive compounds, and their characterization by various spectroscopic methods
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM3341
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry ( Disciplinary Elective ) 2025 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry < PLO 2,3,4 > 2025 Major in Chemistry (Intensive) < PLO 2,3,4 > 2024 Major in Chemistry < PLO 2,3,4 > 2024 Major in Chemistry (Intensive) < PLO 2,3,4 > 2023 Major in Chemistry < PLO 2,3,4 > 2023 Major in Chemistry (Intensive) < PLO 2,3,4 > 2022 Major in Chemistry < PLO 2,3,4 > 2022 Major in Chemistry (Intensive) < PLO 2,3,4 > 2021 Major in Chemistry < PLO 2,3,4 > 2021 Major in Chemistry (Intensive) < PLO 2,3,4 >
Offer in 2025 - 2026	Y        1st sem	Examination	Dec
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough knowledge and understanding of essential facts, concepts, principles, and theories relating to the more detailed and advanced treatment of organometallic chemistry, especially those related to structure, bonding and reactivities of main group and transition metal organometallics; transition metal cluster chemistry; and application of organometallics in organic synthesis and catalysis. Show strong ability to apply and integrate knowledge and theory relating to the advanced principles and concepts of organometallic chemistry. Show strong ability to analyze novel problems and critical use of data and experimental results to draw appropriate and insightful conclusions relating to the advanced principles and applications of organometallic chemistry. Demonstrate highly effective advanced laboratory skills and techniques, especially in the synthesis and manipulation of air- and moisture- sensitive compounds and their characterization by various spectroscopic methods. B Demonstrate substantial command of knowledge and understanding of essential facts, concepts, principles, and theories relating to the more detailed and advanced treatment of organometallic chemistry, especially those related to structure, bonding and reactivities of main group and transition metal organometallics; transition metal cluster chemistry; and application of organometallics in organic synthesis and catalysis. Show evidence to apply and integrate knowledge and theory relating to the advanced principles and concepts of organometallic chemistry. Show evidence to analyze novel problems and correct use of data and experimental results to draw appropriate conclusions relating to the advanced principles and applications of organometallic chemistry. Demonstrate effective advanced laboratory skills and techniques, especially in the synthesis and manipulation of air- and moisture- sensitive compounds and their characterization by various spectroscopic methods. C Demonstrate general but incomplete command of knowledge and understanding of essential facts, concepts, principles, and theories relating to the more detailed and advanced treatment of organometallic chemistry, especially those related to structure, bonding and reactivities of main group and transition metal organometallics; transition metal cluster chemistry; and application of organometallics in organic synthesis and catalysis. Show evidence of some abilities to apply and integrate knowledge and theory relating to the advanced principles and concepts of organometallic chemistry. Show ability to analyze problems to most familiar situations and mostly correct but erroneous use of data and experimental results to draw appropriate conclusions relating to the advanced principles and applications of organometallic chemistry. Demonstrate moderately effective advanced laboratory skills and techniques, especially in the synthesis and manipulation of air- and moisture- sensitive compounds and their characterization by various spectroscopic methods. D Demonstrate partial but limited command of knowledge and understanding of essential facts, concepts, principles, and theories relating to the more detailed and advanced treatment of organometallic chemistry, especially those related to structure, bonding and reactivities of main group and transition metal organometallics; transition metal cluster chemistry; and application of organometallics in organic synthesis and catalysis. Show evidence of limited abilities to apply and integrate knowledge and theory relating to the advanced principles and concepts of organometallic chemistry. Show limited ability to analyze problems to most familiar situations and mostly correct but erroneous use of data and experimental results to draw appropriate conclusions relating to the advanced principles and applications of organometallic chemistry. Demonstrate partially effective advanced laboratory skills and techniques, especially in the synthesis and manipulation of air- and moisture- sensitive compounds and their characterization by various spectroscopic methods. Fail Demonstrate little or no evidence of command of knowledge and understanding of essential facts, concepts, principles, and theories relating to the more detailed and advanced treatment of organometallic chemistry, especially those related to structure, bonding and reactivities of main group and transition metal organometallics; transition metal cluster chemistry; and application of organometallics in organic synthesis and catalysis. Show little or no evidence of abilities to apply and integrate knowledge and theory relating to the advanced principles and concepts of organometallic chemistry. Show little or no ability to analyze problems to most familiar situations and erroneous use of data and experimental results to draw appropriate conclusions relating to the advanced principles and applications of organometallic chemistry. Demonstrate minimally effective advanced laboratory skills and techniques, especially in the synthesis and manipulation of air- and moisture- sensitive compounds and their characterization by various spectroscopic methods.
Communication-intensive Course	N
Course Type	Lecture with laboratory component course
Course Teaching & Learning Activities	Activities Details No. of Hours Laboratory 30.0 Lectures 24.0 Tutorials 5.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments 15.0 1,2,3,4 Examination 50.0 1,2,3,4 Laboratory reports 20.0 1,2,3,4 Test 15.0 1,2,3,4
Required/recommended reading and online materials	R. H. Crabtree: The Organometallic Chemistry of the Transition Metals (Wiley, 2005, 4th ed.) C. Elschenbroich and A. Salzer: Organometallics - A Concise Introduction (VCH, 1992, 2nd revised edition) Reference to specialist texts and other published materials will be made throughout the course.
Course Website	NIL
Additional Course Information	Laboratory classes are mandatory.  Students must complete ALL experiments and laboratory reports to pass this course.

CHEM4441 Advanced organic chemistry (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	40
Course Co-ordinator	Prof J He, Chemistry < jianhe@hku.hk >
Teachers Involved	(Prof J He,Chemistry) (Prof Z X Huang,Chemistry)
Course Objectives	To provide students with knowledge in organic chemistry reaction mechanisms and organic compound structure determination.
Course Contents & Topics	The course covers chemical bonding, advanced stereochemistry, conformational analysis, techniques for investigating reaction mechanisms, reactive intermediates, rearrangement reactions, and pericyclic reactions.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 describe, analyze and interpret the structure and reactivity relationship of organic molecules CLO 2 identify and predict the selectivities (chemoselectivity, regioselectivity and stereoselectivity) in organic reactions CLO 3 describe the general approaches to study organic mechanisms CLO 4 have a general understanding and working knowledge of pericyclic reactions, reactive intermediates (radicals, carbenes and nitrenes), and polar rearrangements CLO 5 suggest reasonable mechanistic pathways for some types of organic reactions CLO 6 apply the knowledge of reaction mechanisms in design of synthetic routes for organic compounds
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM3441
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry ( Disciplinary Elective ) 2025 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry < PLO 1,2,5 > 2025 Major in Chemistry (Intensive) < PLO 1,2,5 > 2024 Major in Chemistry < PLO 1,2,5 > 2024 Major in Chemistry (Intensive) < PLO 1,2,5 > 2023 Major in Chemistry < PLO 1,2,5 > 2023 Major in Chemistry (Intensive) < PLO 1,2,5 > 2022 Major in Chemistry < PLO 1,2,5 > 2022 Major in Chemistry (Intensive) < PLO 1,2,5 > 2021 Major in Chemistry < PLO 1,2,5 > 2021 Major in Chemistry (Intensive) < PLO 1,2,5 >
Offer in 2025 - 2026	Y        1st sem	Examination	Dec
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough mastery at an advanced level of extensive knowledge and skills required for attaining all the course learning outcomes. Show strong analytical and critical abilities and logical thinking, with evidence of original thought, and ability to apply knowledge to a wide range of complex, familiar and unfamiliar situations. B Demonstrate substantial command of a broad range of knowledge and skills required for attaining at least most of the course learning outcomes. Show evidence of analytical and critical abilities and logical thinking, and ability to apply knowledge to familiar and some unfamiliar situations. C Demonstrate general but incomplete command of knowledge and skills required for attaining most of the course learning outcomes. Show evidence of some analytical and critical abilities and logical thinking, and ability to apply knowledge to most familiar situations. D Demonstrate partial but limited command of knowledge and skills required for attaining some of the course learning outcomes. Show evidence of some coherent and logical thinking, but with limited analytical and critical abilities. Show limited ability to apply knowledge to solve problems. Fail Demonstrate little or no evidence of command of knowledge and skills required for attaining the course learning outcomes. Lack of analytical and critical abilities, logical and coherent thinking. Show very little or no ability to apply knowledge to solve problems.
Communication-intensive Course	N
Course Type	Lecture-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Lectures 36.0 Tutorials 12.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments 25.0 1,2,3,4,5,6 Examination 50.0 1,2,3,4,5,6 Test 25.0 1,2,3,4,5,6
Required/recommended reading and online materials	F.A. Carey and R.J. Sunberg, "Advanced Organic Chemistry, Part-A: Structure and Mechanism", 5th Ed.: Springer, 2007. "Organic Chemistry", by Paula Y. Bruice, 2016, 8th Edition, Pearson, with e-text and Mastering Chemistry. I. Fleming, "Pericyclic Reactions", Oxford University Press, 1999.
Course Website	NIL
Additional Course Information	This course is also offered to RPg students, and the course code for RPg students is CHEM6114.

CHEM4443 Integrated organic synthesis (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	50
Course Co-ordinator	Prof Z X Huang, Chemistry < huangzx@hku.hk >
Teachers Involved	(Prof Z X Huang,Chemistry)
Course Objectives	To introduce aspects of modern organic reactions with relevance to and in the context of the synthesis of natural products, drugs and medicinal chemistry to provide an integrated approach to the subject, and to provide training in advanced organic laboratory skills, and further hands-on experience in synthesis and characterization, as preparation for graduate studies or research in organic chemistry.
Course Contents & Topics	Building on the organic chemistry covered in the foundational courses CHEM1003 and CHEM2402, this course will present modern synthetic methods and synthetic planning.  The course is organized into units based on target drug molecules.  In each unit, the chemical biology of these compounds are briefly presented and the syntheses of these molecules are introduced, accompanied by in-depth discussions of the reactions involved with emphasis on their mechanisms, selectivity, stereochemistry, scope and limitations. Concept of synthetic design including retrosynthetic analysis, stereoselectivity and enantioselective control elements will be emphasized.  A laboratory section provides training in the practical skills of synthesis.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 understand the rationale, selectivities, and mechanisms of various reactions and reagents in organic chemistry CLO 2 able to solve mechanistic and synthetic chemistry problems CLO 3 perform organic synthesis experiments at an increased level of technical difficulty, using additional skills in experimental design and execution, spectroscopic analysis, and reporting of results CLO 4 integrate lecture material and literature search, to learn chemistry independently
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM3441; or Pass in CHEM3441 (without lab component) and CHEM3443
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry ( Disciplinary Elective ) 2025 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry < PLO 1,2,3,4 > 2025 Major in Chemistry (Intensive) < PLO 1,2,3,4 > 2024 Major in Chemistry < PLO 1,2,3,4 > 2024 Major in Chemistry (Intensive) < PLO 1,2,3,4 > 2023 Major in Chemistry < PLO 1,2,3,4 > 2023 Major in Chemistry (Intensive) < PLO 1,2,3,4 > 2022 Major in Chemistry < PLO 1,2,3,4 > 2022 Major in Chemistry (Intensive) < PLO 1,2,3,4 > 2021 Major in Chemistry < PLO 1,2,3,4 > 2021 Major in Chemistry (Intensive) < PLO 1,2,3,4 >
Offer in 2025 - 2026	Y        2nd sem	Examination	May
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate a thorough mastery at an advanced level of knowledge and understanding of concepts, principles, reactions and mechanisms related to synthetic organic chemistry. Show a strong ability to integrate knowledge and theory, and a strong ability to analyze novel synthetic organic chemistry situations and problems. Show a critical use of knowledge and data to apply to the solution of novel and complex synthetic problems. Demonstrate highly effective organization and application of lab skills and techniques in synthetic experiments. B Demonstrate a substantial command of knowledge and understanding of concepts, principles, reactions and mechanisms related to synthetic organic chemistry. Show evidence of ability to integrate knowledge and theory, and evidence of ability to analyze synthetic organic chemistry situations and problems. Show a correct use of knowledge and data to apply to the solution of some novel and most familiar synthetic problems. Demonstrate effective organization and application of lab skills and techniques in synthetic experiments. C Demonstrate a general but incomplete command of knowledge and understanding of concepts, principles, reactions and mechanisms related to synthetic organic chemistry. Show evidence of some ability to integrate knowledge and theory, and evidence of some ability to analyze synthetic organic chemistry situations and problems. Show a correct use of knowledge to apply to the solution of most familiar problems. Demonstrate moderately effective organization and application of lab skills and techniques in synthetic experiments. D Demonstrate a partial but limited command of knowledge and understanding of concepts, principles, reactions and mechanisms related to synthetic organic chemistry. Show evidence of a limited ability to integrate knowledge and theory, and a limited ability to analyze familiar situations and problems. Show some correct but erroneous use of knowledge to apply to the solution of most familiar problems. Demonstrate partially effective organization and application of lab skills and techniques in synthetic experiments. Fail Demonstrate little or no evidence of command of knowledge and understanding of concepts, principles, reactions and mechanisms related to synthetic organic chemistry. Show little or no evidence of ability to integrate knowledge and theory in synthetic organic chemistry, and little or no ability to analyze most familiar situations and problems. Show mostly erroneous use of knowledge to apply to the solution of familiar problems. Demonstrate minimally effective organization and application of lab skills and techniques in synthetic experiments.
Communication-intensive Course	N
Course Type	Lecture with laboratory component course
Course Teaching & Learning Activities	Activities Details No. of Hours Laboratory 25.0 Lectures 24.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments (Problem sets) 10.0 1,2,4 Examination 50.0 1,2,3,4 Laboratory reports (Practicals & lab test) 25.0 1,2,3,4 Test 15.0 1,2,4
Required/recommended reading and online materials	Reference Books: Organic synthesis, C. Willis, M. Wills, Oxford Science Publications Top drugs, top synthetic routes, J. Saunders, Oxford Science Publications
Course Website	NIL
Additional Course Information	Laboratory classes are mandatory.  Students must complete ALL experiments and laboratory reports to pass this course. This course is also offered to RPg students, and the course code for RPg students is CHEM6111.

CHEM4444 Chemical biology (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	50
Course Co-ordinator	Prof X C Li, Chemistry < xuechenl@hku.hk >
Teachers Involved	(Prof X C Li,Chemistry)
Course Objectives	To understand how to use chemical approaches to emulate biological systems to study natural molecules and generate new functional molecules.  Useful as an introduction to research in areas of chemical biology, medicinal chemistry and biotechnology.
Course Contents & Topics	Chemical biology of nucleic acids, protein chemistry, protein posttranslational modifications, carbohydrate chemistry, chemical glycobiology and tools and techniques in chemical biology.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 understand chemical biology approaches in studying biology CLO 2 give examples of how to use chemical methods to produce natural biomolecules and new biomolecules wiht altered functions CLO 3 compare chemical biology and traditional biology approaches in drug discovery
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in BIOC3601 or CHEM3441
Course Status with Related Major/Minor /Professional Core	2025 Major in Biochemistry ( Disciplinary Elective ) 2025 Major in Chemistry ( Disciplinary Elective ) 2025 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2025 Minor in Biochemistry ( Disciplinary Elective ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Biochemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2024 Minor in Biochemistry ( Disciplinary Elective ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Biochemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2023 Minor in Biochemistry ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Biochemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2022 Minor in Biochemistry ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Biochemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2021 Minor in Biochemistry ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Biochemistry < PLO 1,2,3,4,5 > 2025 Major in Chemistry < PLO 1,2,6 > 2025 Major in Chemistry (Intensive) < PLO 1,2,6 > 2024 Major in Biochemistry < PLO 1,2,3,4,5 > 2024 Major in Chemistry < PLO 1,2,6 > 2024 Major in Chemistry (Intensive) < PLO 1,2,6 > 2023 Major in Biochemistry < PLO 1,2,3,4,5 > 2023 Major in Chemistry < PLO 1,2,6 > 2023 Major in Chemistry (Intensive) < PLO 1,2,6 > 2022 Major in Biochemistry < PLO 1,2,3,4,5 > 2022 Major in Chemistry < PLO 1,2,6 > 2022 Major in Chemistry (Intensive) < PLO 1,2,6 > 2021 Major in Biochemistry < PLO 1,2,3,4,5 > 2021 Major in Chemistry < PLO 1,2,6 > 2021 Major in Chemistry (Intensive) < PLO 1,2,6 >
Offer in 2025 - 2026	Y        2nd sem	Examination	May
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough mastery at an advanced level of extensive knowledge and skills required for attaining all the course learning outcomes. Show strong analytical and critical abilities and logical thinking, with evidence of original thought, and ability to apply knowledge to a wide range of complex, familiar and unfamiliar situations. Apply highly effective organizational and presentational skills. Insightful use and critical analysis / evaluation of information drawn from a full range of high quality sources and to quote/reference aptly. B Demonstrate substantial command of a broad range of knowledge and skills required for attaining at least most of the course learning outcomes. Show evidence of analytical and critical abilities and logical thinking, and ability to apply knowledge to familiar and some unfamiliar situations. Apply effective organizational and presentational skills. Critical use of relevant information from sources, showing ability to make meaningful comparisons between different secondary interpretations and to quote/reference aptly. C Demonstrate general but incomplete command of knowledge and skills required for attaining most of the course learning outcomes. Show evidence of some analytical and critical abilities and logical thinking, and ability to apply knowledge to most familiar situations. Apply moderately effective organizational and presentational skills. Use of relevant information from sources, showing ability to make comparisons between different interpretations and to quote/reference aptly. D Demonstrate partial but limited command of knowledge and skills required for attaining some of the course learning outcomes. Show evidence of some coherent and logical thinking, but with limited analytical and critical abilities. Show limited ability to apply knowledge to solve problems. Apply limited or barely effective organizational and presentational skills. Use and reference of several sources, but mainly through summary rather than analysis and comparison. Fail Demonstrate little or no evidence of command of knowledge and skills required for attaining the course learning outcomes. Lack of analytical and critical abilities, logical and coherent thinking. Show very little or no ability to apply knowledge to solve problems. Organization and presentational skills are minimally effective or ineffective. Limited use of secondary sources and no critical comparison of them.
Communication-intensive Course	N
Course Type	Lecture-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Lectures 36.0 Tutorials (tutorials/discussion) 12.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments 5.0 1,2,3 Examination 50.0 1,2,3 Presentation 25.0 1,2,3 Test 20.0 1,2,3
Required/recommended reading and online materials	Foundations of Chemical Biology by C.M. Dobson, J.A. Gerrard and A.J. Pratt.
Course Website	Nil
Additional Course Information	Nil

   <<< This course is not offered in 2025-2026. Course details are subject to change. >>>

CHEM4541 Physical chemistry III: statistical thermodynamics and kinetics theory (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	40
Course Co-ordinator	---, Chemistry
Teachers Involved
Course Objectives	The course presents fundamental principles and topics on statistical thermodynamics and kinetic theory in order to provide a solid foundation for students intending to further their studies in physical chemistry and related fields.
Course Contents & Topics	Principles of Statistical Thermodynamics - Thermodynamic laws - Ensembles and partition functions: microcanonical, canonical and grand-canonical - Systems of independent molecules: ideal gas - Molecular degrees of freedom: translation, rotation, vibration, and electronic - Ideal gas mixture: chemical equilibrium, binding, and titration - Lattice statistics: Ising model and phase transition - Quantum statistics Chemical equilibrium and kinetics theory - Rate theory: collision theory, transition state theory
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 understand and use the terminology and nomenclature in statistical thermodynamics and topics discussed in the course CLO 2 demonstrate knowledge and understanding of basic concepts in statistical thermodynamics CLO 3 understand correlation between macroscopic observables and microscopic statistical model systems
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM3541
Course to PLO Mapping
Offer in 2025 - 2026	N	Examination
Offer in 2026 - 2027	N
Course Grade	A+ to F
Grade Descriptors	A Thorough mastery at an advanced level of extensive knowledge of statistical thermodynamics and reaction dynamics. Demonstrate evidence of strong analytical / critical abilities and logical thinking. Can apply the knowledge to practical questions in Physical Chemistry. B Substantial command of knowledge of statistical thermodynamics and reaction dynamics. Demonstrate evidence of analytical / critical abilities and logical thinking. Understand the scope of Physical Chemistry questions that can be applied with the knowledge. C General but incomplete command of knowledge of statistical thermodynamics and reaction dynamics. Demonstrate evidence of analytical thinking. Can apply the knowledge to familiar situations. D Partial but limited command of knowledge of knowledge of statistical thermodynamics and reaction dynamics. Demonstrate limited evidence of analytical thinking. Understand the question to be solved with knowledge. Fail Little or no evidence of command of knowledge of statistical thermodynamics and reaction dynamics.
Communication-intensive Course	N
Course Type	Lecture with laboratory component course
Course Teaching & Learning Activities	Activities Details No. of Hours Laboratory 24.0 Lectures 24.0 Tutorials 6.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments continuous assessment of on class quizzes & assignments 40.0 1,2,3 Examination 60.0 1,2,3
Required/recommended reading and online materials	T. L. Hill, An introduction to Statistical Thermodynamics P. Atkins, Physical Chemistry
Course Website	NIL
Additional Course Information	Laboratory classes are mandatory.  Students must complete ALL experiments and laboratory reports to pass this course.

CHEM4542 Computational chemistry (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	50
Course Co-ordinator	Prof J Yang, Chemistry < juny@hku.hk >
Teachers Involved	(Prof J Yang,Chemistry)
Course Objectives	This course covers common topics in computational chemistry including molecular quantum chemistry and dynamics methods as well as the fundamental in machine learning. Topics include basic concepts, computational theories and practical problems in chemistry. It is offered to undergraduate and postgraduate students who are interested in advanced computational chemistry techniques.
Course Contents & Topics	Force field MM method, Hartree-Fock theory, density functional theory, basis sets, post-HF methods, QM/MM method, quantum chemistry programs, python modules for machine learning, regression method, clustering, K-nearest neighbors, deep neural network and machine learning applications to computational chemistry.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 understand the basic concepts of density-functional theory CLO 2 understand the basic numerical techniques of molecular mechanics method and quantum mechanics/molecular mechanics method CLO 3 employ the existing computational software to calculate the chemical, physical properties of various molecular systems include organic molecules, inorganic materials and biomolecules
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM3541 and CHEM1044
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry ( Disciplinary Elective ) 2025 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry < PLO 1,2,3,5 > 2025 Major in Chemistry (Intensive) < PLO 1,2,3,5 > 2024 Major in Chemistry < PLO 1,2,3,5 > 2024 Major in Chemistry (Intensive) < PLO 1,2,3,5 > 2023 Major in Chemistry < PLO 1,2,3,5 > 2023 Major in Chemistry (Intensive) < PLO 1,2,3,5 > 2022 Major in Chemistry < PLO 1,2,3,5 > 2022 Major in Chemistry (Intensive) < PLO 1,2,3,5 > 2021 Major in Chemistry < PLO 1,2,3,5 > 2021 Major in Chemistry (Intensive) < PLO 1,2,3,5 >
Offer in 2025 - 2026	Y        1st sem	Examination	No Exam
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Mastery of an advanced level of extensive knowledge and skills required on all course topics. Show strong analytical and critical abilities and logical thinking, with strong ability to apply knowledge to practical problems in computational chemistry. Demonstrate highly effective organizational and presentation skills. B Substantial command of a broad range of knowledge on most of the course topics. Show evidence of analytical and critical abilities and logical thinking, with reasonable ability to apply knowledge to practical problems in computational chemistry. Demonstrate effective organizational and presentation skills. C Demonstrate general but incomplete command of a range of knowledge on most of the course topics. Show evidence of some analytical abilities and logical thinking, with ability to apply knowledge to practical problems in computational chemistry. Demonstrate moderate organizational and presentation skills. D Demonstrate partial and limited command of knowledge on some of the course topics. Show evidence of some coherent analytical ability and logical thinking, with limited ability to apply knowledge to practical problems in computational chemistry. Demonstrate partially effective organizational and presentation skills. Fail Little or no evidence of command of knowledge on the course topic. Lack of analytical and critical abilities and logical thinking, with very little or no ability to apply knowledge to practical problems in computational chemistry. Demonstrate minimal or ineffective organizational and presentation skills.
Communication-intensive Course	N
Course Type	Lecture with laboratory component course
Course Teaching & Learning Activities	Activities Details No. of Hours Laboratory lab sessions 6x4 hours of computational laboratory 24.0 Lectures 24.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Examination Midterm Project 10.0 1,2,3 Laboratory reports 4x10% 40.0 1,2,3 Project report Final project 50.0 1,2,3
Required/recommended reading and online materials	D. Young: Computational Chemistry A Practical Guide for Applying Techniques to Real-world Problems F. Jensen: Introduction to Computational Chemistry J. Kinder & P. Nelson: A Student’s Guide to Python for Physical Modelling A. Geron: Hands-on Machine Learning with Scikit-learn and Tensorflow: Concepts, Tools, and Techniques to Build Intelligent Systems
Course Website	NIL
Additional Course Information	CHEM4542 is offered every year in Semester 1. Laboratory classes, midterm and final projects are mandatory. Students must complete ALL experiments and laboratory reports to pass this course.

CHEM4543 Advanced physical chemistry (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	40
Course Co-ordinator	Prof G H Chen, Chemistry < ghc@yangtze.hku.hk >
Teachers Involved	(Prof D L Phillips,Chemistry) (Prof G H Chen,Chemistry)
Course Objectives	This course covers advanced topics in physical chemistry.  It is offered for students majoring in physical chemistry and for students who are interested in postgraduate studies.
Course Contents & Topics	Time-resolved spectroscopy methods, excited states and reactive intermediates, photophysics and photochemical processes, chemical reaction mechanisms, advanced quantum mechanical methods, reaction pathways and surface crossings.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 understand the basic concepts of quantum chemistry, statistical thermodynamics and molecular dynamics CLO 2 understand Hartree-Fock method, statistical ensembles, quantum statistics, H-theorem, and reaction dynamics CLO 3 understand the elementary numerical procedures in Hartree-Fock and molecular mechanics methods
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM3541
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry ( Disciplinary Elective ) 2025 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry < PLO 1,2,3,5 > 2025 Major in Chemistry (Intensive) < PLO 1,2,3,5 > 2024 Major in Chemistry < PLO 1,2,3,5 > 2024 Major in Chemistry (Intensive) < PLO 1,2,3,5 > 2023 Major in Chemistry < PLO 1,2,3,5 > 2023 Major in Chemistry (Intensive) < PLO 1,2,3,5 > 2022 Major in Chemistry < PLO 1,2,3,5 > 2022 Major in Chemistry (Intensive) < PLO 1,2,3,5 > 2021 Major in Chemistry < PLO 1,2,3,5 > 2021 Major in Chemistry (Intensive) < PLO 1,2,3,5 >
Offer in 2025 - 2026	Y        2nd sem	Examination	May
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Mastery of advanced knowledge on following topics: variation method in quantum mechanics, Hartree-Fock method, perturbation theory, advanced statistical thermodynamics, reaction dynamics. Strong analytical and critical abilities and logical thinking, with strong ability to apply knowledge to practical problems in physical chemistry. B Substantial command of a broad range of knowledge on following topics: variation method in quantum mechanics, Hartree-Fock method, perturbation theory, advanced statistical thermodynamics, reaction dynamics. Evidence of analytical and critical abilities and logical thinking, with ability to apply knowledge to practical problems in physical chemistry. C Command of knowledge on following topics: variation method in quantum mechanics, Hartree-Fock method, perturbation theory, advanced statistical thermodynamics, reaction dynamics. Evidence of some analytical and critical abilities and logical thinking, with ability to apply knowledge to familiar problems in physical chemistry. D Partial but limited command of knowledge on following topics: variation method in quantum mechanics, Hartree-Fock method, perturbation theory, advanced statistical thermodynamics, reaction dynamics. Evidence of some coherent analytical and critical abilities and logical thinking, with limited ability to apply knowledge to practical problems in physical chemistry. Fail Little or no evidence of command of knowledge on following topics: variation method in quantum mechanics, Hartree-Fock method, perturbation theory, advanced statistical thermodynamics, reaction dynamics. Lack of analytical and critical abilities and logical thinking, with very little or no ability to apply knowledge to practical problems in physical chemistry.
Communication-intensive Course	N
Course Type	Lecture-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Lectures 36.0 Tutorials tutorials/discussion 12.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments (continuous assessment/test) 50.0 1,2,3 Examination 50.0 1,2,3
Required/recommended reading and online materials	P. W. Atkins: Physical Chemistry Ira N. Levine: Quantum Chemistry (Prentice Hall, 4th ed.) R. C. Tolman: The Principles of Statistical Mechanics R. D. Levine, R. B. Bernstein: Molecular Reaction Dynam
Course Website	Nil
Additional Course Information	This course is also offered to RPg students, and the course code for RPg students is CHEM6112.

   <<< This course is not offered in 2025-2026. Course details are subject to change. >>>

CHEM4544 Electrochemical science and technology (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	36
Course Co-ordinator	Prof G K Y Chan, Chemistry < hrsccky@hku.hk >
Teachers Involved	(Prof G K Y Chan,Chemistry) (Visiting Professor,Chemistry)
Course Objectives	To understand the science of electrochemistry, methods to characterise electrochemical cells, and factors affecting electrochemical applications and technologies.
Course Contents & Topics	Thermodynamics, kinetics, and transport of electrochemical processes. Electrochemical characterization by controlled potential, current, and hydrodynamics.  Voltammetry for analytical chemistry. Electrochemical power sources, sensors, synthesis and separation processes. Electrolytes, separators, and electrode materials. Models of electrochemical processes.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 Understand the thermodynamic and kinetics of a charge transfer process at the electrode-electrolyte interface and transport of relevant species in molecular and macroscopic scales. CLO 2 Apply voltammetry methods to characterize an electrochemical process. CLO 3 Correlate performance of electrochemical cells to materials, design, and operation parameters.
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in CHEM3241 or CHEM3541 or CHEM3542
Course Status with Related Major/Minor /Professional Core	2U000C00 Course not offered under any Major/Minor/Professional core 2023 Major in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2023 Major in Chemistry < PLO 2 > 2023 Major in Chemistry (Intensive) < PLO 2 > 2022 Major in Chemistry < PLO 2 > 2022 Major in Chemistry (Intensive) < PLO 2 > 2021 Major in Chemistry < PLO 2 > 2021 Major in Chemistry (Intensive) < PLO 2 >
Offer in 2025 - 2026	N	Examination
Offer in 2026 - 2027	N
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough knowledge of electrochemical science and technology, and mastery of skills required for attaining all of the course learning outcomes. Show strong analytical and critical abilities and logical thinking, with evidence of original thought, and ability to apply knowledge to solve problems in a wide range of complex, familiar and unfamiliar situations. Critical use of data and sourcing of references. Apply highly effective organizational and presentational skills. B Demonstrate substantial knowledge of electrochemical science and technology and command of skills required for attaining at least most of the course learning outcomes. Show evidence of analytical and critical abilities and logical thinking, and ability to apply knowledge to solve problems in familiar and some unfamiliar situations. Correct use of data and sourcing of references. Apply effective organizational and presentational skills. C Demonstrate general but incomplete knowledge of electrochemical science and technology and command of skills required for attaining most of the course learning outcomes. Show evidence of some analytical and critical abilities and logical thinking, and ability to apply knowledge solve problems to most familiar situations. Mostly correct but some erroneous use of data and references. Apply moderately effective organizational and presentational skills. D Demonstrate partial but limited knowledge of electrochemical science and technology and command of skills required for attaining some of the course learning outcomes. Show evidence of some coherent and logical thinking, but with limited analytical and critical abilities. Show limited ability to apply knowledge to solve problems. Limited ability to use data and source references. Apply limited or barely effective organizational and presentational skills. Fail Demonstrate little or no evidence of knowledge of electrochemical science and technology, and command of skills required for attaining the course learning outcomes. Lack of analytical and critical abilities, logical and coherent thinking. Show very little or no ability to apply knowledge to solve problems. Misuse of data and references. Organization and presentational skills are minimally effective or ineffective.
Communication-intensive Course	N
Course Type	Lecture with laboratory component course
Course Teaching & Learning Activities	Activities Details No. of Hours Laboratory Laboratory/Project 24.0 Lectures 24.0 Tutorials 6.0 Reading / Self study 100.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Assignments 10.0 1,2,3 Examination 50.0 1,2,3 Laboratory reports (Laboratory or Project Report/Term Paper) 10.0 1,2,3 Test (Test/ Quiz) 30.0 1,2,3
Required/recommended reading and online materials	K. B. Oldham, J. C. Myland, and A. B. Bond, Electrochemical Science and Technology, John Wiley & Sons, 2012, ISBN 978047071045. Bard, Allen J., Larry R. Faulkner. Electrochemical Methods: Fundamentals and Applications. 2nd Ed. Wiley, 2000. ISBN: 9780471043720.
Course Website
Additional Course Information	This course is offered every other year.

CHEM4910 Chemistry literacy and research (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	---
Course Co-ordinator	Prof X D Li, Chemistry < xiangli@hku.hk >
Teachers Involved	(Various teachers in the Department,Chemistry)
Course Objectives	This course is designed for final year students who would like to gain experience on research methods and techniques by working on small projects on literature research and chemistry research.
Course Contents & Topics	The course provides training on chemistry literature research techniques. Students will work on a small project on literature research and a short laboratory-based research project. The laboratory-based projects are provided by the students' supervisors who are assigned by the department.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 demonstrate knowledge of academic databases and search engines of chemistry literature CLO 2 understand the terminology and nomenclature associated with their own research project CLO 3 demonstrate knowledge and understanding of the chemical techniques they used to do the research in their own research project CLO 4 demonstrate knowledge and understanding of the results of their own research project and its context in the broader research area
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in at least 24 credits of advanced level disciplinary core/elective chemistry courses (CHEM3XXX or CHEM4XXX) in the Chemistry Major including CHEM3241, and CHEM3341, and CHEM3441, and CHEM3541. This capstone course is for Chemistry Major students only. The earliest that a student is allowed to take this capstone course is their year 3 study.
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry ( Disciplinary Elective ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Disciplinary Elective ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry < PLO 1,2,3,4,5,6 > 2024 Major in Chemistry < PLO 1,2,3,4,5,6 > 2023 Major in Chemistry < PLO 1,2,3,4,5,6 > 2022 Major in Chemistry < PLO 1,2,3,4,5,6 > 2021 Major in Chemistry < PLO 1,2,3,4,5,6 >
Offer in 2025 - 2026	Y        2nd sem	Examination	No Exam
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Show an extensive comprehension of the research project. Demonstrate very able analytical and critical thought with presence of some originality. Illuminating utilization and critical analysis / evaluation of information acquired from a wide range of high quality sources. Critical employment of data and results to synthesize appropriate and illuminating conclusions. Demonstrate integration of a wide range of appropriate theories, principles, data and methods. Employ very effective organizational and presentational skills. [Work of A+ should demonstrate substantial additional work beyond that is required in wider areas relevant to the topic.] B Show a substantial comprehension of the research project. Demonstrate able analytical and critical thinking with use of relevant information from sources. Demonstrate ability to compose meaningful comparisons between different secondary interpretations. Correct utilization of data and results to form appropriate conclusions. Compose general integration of theories, principles, data and methods. Perform effective organizational and presentational skills. C Show a general but incomplete comprehension of the research project. Presence of some analytical and critical thinking with use of relevant information from sources. Demonstrate ability to compose comparisons between different interpretations. Mainly correct but some incorrect utilization of data and results to form appropriate conclusions. Demonstrate some partial integration of theories, principles, data and methods. Perform moderately effective organizational and presentational skills. D Show a partial but limited comprehension, with knowledge of some relevant information, of the research project. Presence of some coherent and logical thinking, but with limited analytical and critical abilities. Show utilization and reference of several sources, but mostly via summary instead of by analysis and comparison. Limited ability to employ data and results to form appropriate conclusions. Demonstrate limited integration of theories, principles, data and methods. Perform limited or marginally effective organizational and presentational skills. Fail Show little or no comprehension of the research project. Evidence of little or lack of analytical and critical abilities, logical and coherent thinking. Limited employment of secondary sources and no critical comparison of them. Incorrectly utilize data and results and/or unable to form appropriate conclusions. Demonstrate little or no integration of theories, principles, data and methods. Organization and presentational skills are of very limited use or ineffective.
Communication-intensive Course	N
Course Type	Project-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Reading / Self study 12 hrs tutorials; 46 hrs of workshops and 100 hrs reading/self study 158.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Oral presentation 50.0 1,2,3,4 Research report 50.0 1,2,3,4
Required/recommended reading and online materials	Reading materials will be assigned depending on the project.
Course Website	NIL
Additional Course Information	Satisfactory completion of this course will be counted towards the Capstone requirement.

CHEM4911 Capstone experience for chemistry undergraduates: HKUtopia (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	---
Course Co-ordinator	Dr A T L Li, Chemistry < litla@hku.hk >
Teachers Involved	(Various teachers in the Department,Chemistry)
Course Objectives	This project-based course with the theme of Chemistry for a Better Living in a Foreseeable Future aims to provide students with a capstone experience. It aims to enable students to think what are the key issues the world is facing with that have to be solved by chemistry and related technology.  Students will need to apply what they have learnt in classroom and conduct literature search regarding advanced chemistry research and related technology under development to solve the problems identified in their project using various channels.
Course Contents & Topics	No formal teaching. It is expected that students are actively engaged and should devote no less than 160 hours to working on this project. Students will work in groups of two or three, under the supervision of the course coordinator.  The duration of the project will be two to three months.  The time of running this project-based course is in the summer (May - August).
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 describe and explain the major issues we are facing with and determine ways in which chemistry can be used to solve the problems using both written and oral formats CLO 2 integrate theory and practice, and to understand limitations of their current knowledge CLO 3 work in a team and to collaborate with people with different background CLO 4 develop further logical, critical thinking and creativity CLO 5 express scientific ideas and present findings of the project in both individual written report and collaborative oral presentation CLO 6 advocate to others the appreciation for chemistry as to its relevance to our daily life
Pre-requisites (and Co-requisites and Impermissible combinations)	Students are expected to have satisfactorily completed all introductory chemistry disciplinary core courses and at least 24 credits of advanced level disciplinary core/elective chemistry courses in the Chemistry Major. Students who are interested in taking the course should contact the course coordinator for application in April - May. Late application may not be considered. This capstone course is for Chemistry Major students only. The earliest that a student is allowed to take this capstone course is their year 3 study.
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry ( Disciplinary Elective ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Disciplinary Elective ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry < PLO 1,2,3,4,5 > 2024 Major in Chemistry < PLO 1,2,3,4,5 > 2023 Major in Chemistry < PLO 1,2,3,4,5 > 2022 Major in Chemistry < PLO 1,2,3,4,5 > 2021 Major in Chemistry < PLO 1,2,3,4,5 >
Offer in 2025 - 2026	Y        Summer	Examination	No Exam
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Demonstrate thorough grasp of the subject. Show strong analytical and critical abilities and logical thinking, with evidence of original thought. Insightful use and critical analysis / evaluation of information drawn from a full range of high quality sources and to quote/reference aptly. Critical use of data and results to draw appropriate and insightful conclusions. Show integration of the full range of appropriate theories, principles, evidence and techniques. Apply highly effective organizational and presentational skills. [Work of A+ should show considerable additional work beyond that is required in wider areas relevant to the topic.] B Demonstrate substantial grasp of the subject. Evidence of analytical and critical abilities and logical thinking. Critical use of relevant information from sources, showing ability to make meaningful comparisons between different secondary interpretations and to quote/reference aptly. Correct use of data of results to draw appropriate conclusions. Show general integration of theories, principles, evidence and techniques. Apply effective organizational and presentational skills. C Demonstrate general but incomplete grasp of the subject. Evidence of some analytical and critical abilities and logical thinking. Use of relevant information from sources, showing ability to make comparisons between different interpretations and to quote/reference aptly. Mostly correct but some erroneous use of data and results to draw appropriate conclusions. Show some partial integration of theories, principles, evidence and techniques. Apply moderately effective organizational and presentational skills. D Demonstrate partial but limited grasp, with retention of some relevant information, of the subject. Evidence of some coherent and logical thinking, but with limited analytical and critical abilities. Demonstrate use and reference of several sources, but mainly through summary rather than analysis and comparison. Limited ability to use data and results to draw appropriate conclusions. Show limited integration of theories, principles, evidence and techniques. Apply limited or barely effective organizational and presentational skills. Fail Demonstrate evidence of little or no grasp of the knowledge and understanding of the subject. Evidence of little or lack of analytical and critical abilities, logical and coherent thinking. Limited use of secondary sources and no critical comparison of them. Misuse of data and results and/or unable to draw appropriate conclusions. Show little or no or inapt integration of theories, principles, evidence and techniques. Organization and presentational skills are minimally effective or ineffective.
Communication-intensive Course	Y
Course Type	Project-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Meeting with supervisor Plus tutorials 20.0 Assessment Group work or project 80.0 Reading / Self study 60.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Oral presentation 40% Presentation; 10% Participation; 10% Peer evaluation 60.0 1,2,3,4,5,6 Research report 40.0 1,2,4,5,6
Required/recommended reading and online materials	No specific list of textbooks and references. Students are encouraged to obtain information via various channels (main library, e-journals, internet, and discussions with classmates and teachers, etc.).
Course Website
Additional Course Information	Enrolment of this course is not conducted via the online course selection system and should be made through the relevant Department/School office after approval has been obtained from the course coordinator.

CHEM4966 Chemistry internship (6 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	---
Course Co-ordinator	Dr K K H Ng, Chemistry < kkhn3@hku.hk >
Teachers Involved	(Dr K K H Ng,Chemistry)
Course Objectives	This course aims to offer students the opportunities to gain work experience in the industry related to their major of study.  The workplace learning experience would be of great benefits to the students to apply their knowledge gained in the study to the real work environments.  Students have to take on at least 160 hours of internship work either within the University or outside the University arranged by the School/Departments.
Course Contents & Topics	- Within the University: The student will be supervised by a staff member (Supervisor), working on a project or various tasks as instructed by the Supervisor. - Outside the University: The student will work in an external agency related to the major of study.  The student will be supervised under a staff member of the external agency (the External Supervisor) and a staff member of the Department/School of the student (the Internal Supervisor).  The work to be performed by the student will normally be instructed by the External Supervisor, with prior agreement of the Internal Supervisor.
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 apply knowledge in their major study in solving practical problems in the work place CLO 2 gain first hand work experience in the industry related to their major study
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in at least 24 credits of advanced level disciplinary core/elective chemistry courses (CHEM3XXX or CHEM4XXX) in the Chemistry Major. This capstone course is for Chemistry Major/ Chemistry Major (Intensive) students only. The earliest that a student is allowed to take this capstone course is their year 3 study.
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry ( Disciplinary Elective ) 2025 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry < PLO 1,2,3,4,5,6 > 2025 Major in Chemistry (Intensive) < PLO 1,2,3,4,5,6 > 2024 Major in Chemistry < PLO 1,2,3,4,5,6 > 2024 Major in Chemistry (Intensive) < PLO 1,2,3,4,5,6 > 2023 Major in Chemistry < PLO 1,2,3,4,5,6 > 2023 Major in Chemistry (Intensive) < PLO 1,2,3,4,5,6 > 2022 Major in Chemistry < PLO 1,2,3,4,5,6 > 2022 Major in Chemistry (Intensive) < PLO 1,2,3,4,5,6 > 2021 Major in Chemistry < PLO 1,2,3,4,5,6 > 2021 Major in Chemistry (Intensive) < PLO 1,2,3,4,5,6 >
Offer in 2025 - 2026	Y        1st sem    2nd sem    Summer	Examination	No Exam
Offer in 2026 - 2027	Y
Course Grade	Distinction/Pass/Fail
Grade Descriptors	Distinction Demonstrates excellent ability in applying knowledge to solve problems in the workplace. Demonstrates excellent performance in handling and carrying out the work required in the job or assigned by supervisor(s). Establishes highly effective collaboration and communication with supervisor(s), colleagues, and clients in the job. Successfully fulfills the requirements set out in the Course Description regarding working hours, with excellent performance in written and oral report, and excellent evaluation by supervisor(s), etc. Pass Able to apply knowledge to solve problems in the workplace. Successfully handles and carries out the work required in the job or assigned by supervisor(s). Establishes effective collaboration and communication with supervisor(s), colleagues, and clients in the job. Successfully fulfills the requirements set out in the Course Description regarding working hours, written and oral report, and evaluation by supervisor(s), etc. Students demonstrating excellent performance in the above would be awarded a grade of "Distinction". Fail Very limited or no ability to solve problems in the workplace. Fails to handle or carry out the work required in the job or assigned by supervisor(s). Fails to establish effective collaboration or communication with supervisor(s), other colleagues, or clients in the job. Fails to satisfy the requirements set out in the Course Description regarding working hours, written and oral report, or evaluation by supervisor(s), etc.
Communication-intensive Course	N
Course Type	Internship
Course Teaching & Learning Activities	Activities Details No. of Hours Internship work it is expected that students are to work at least 160 hours (or the equivalent of 4 weeks full-time) 160.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Oral presentation 30.0 1,2 Supervisor's feedback 30.0 1,2 Written report 40.0 1,2
Required/recommended reading and online materials	NIL
Course Website	https://chemistry.hku.hk/staff/kkhn3/4966
Additional Course Information	Satisfactory completion of this course can be counted towards the Capstone requirement.  Details of internship will be recorded on the student's transcript. This course will be assessed on "Pass/Fail" basis. Students who are interested to enrol in this course should contact the Department to obtain the approval. Enrolment of this course is not conducted via the online course selection system and should be made through the relevant Department/School office after approval has been obtained from the course coordinator.

CHEM4999 Chemistry project (12 credits)		Academic Year	2025
Offering Department	Chemistry	Quota	---
Course Co-ordinator	Prof J Y Tang, Chemistry < jinyao@hku.hk >
Teachers Involved	(Various teachers in the Department,Chemistry)
Course Objectives	To provide experience of research techniques by working on a short project under the direct supervision of a member of staff.  This course would prepare students for graduate school work in chemistry.
Course Contents & Topics	A short research project provided by a member of staff (e.g. the students supervisor).
Course Learning Outcomes	On successful completion of this course, students should be able to: CLO 1 understand the terminology and nomenclature associated with their own research chemistry project CLO 2 demonstrate knowledge and understanding of the chemical techniques they used to do the research in their own chemical project CLO 3 demonstrate critical thinking skill in their own research project and understanding the motivation and target of the research CLO 4 demonstrate knowledge and understanding of the results of their own chemistry project and its context in the broader research area CLO 5 demonstrate ability to integrate the knowledge acquired from previous courses and develop fundamental knowledge of designing research plan
Pre-requisites (and Co-requisites and Impermissible combinations)	Pass in at least 24 credits of advanced level disciplinary core/elective chemistry courses (CHEM3XXX or CHEM4XXX) in the Chemistry Major including CHEM3241, and CHEM3341, and CHEM3441, and CHEM3541. This capstone course is for Chemistry Major/ Chemistry Major (Intensive) students only. The earliest that a student is allowed to take this capstone course is their year 3 study.
Course Status with Related Major/Minor /Professional Core	2025 Major in Chemistry ( Disciplinary Elective ) 2025 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2025 Minor in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry ( Disciplinary Elective ) 2024 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2024 Minor in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry ( Disciplinary Elective ) 2023 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2023 Minor in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry ( Disciplinary Elective ) 2022 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2022 Minor in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry ( Disciplinary Elective ) 2021 Major in Chemistry (Intensive) ( Disciplinary Elective ) 2021 Minor in Chemistry ( Disciplinary Elective )
Course to PLO Mapping	2025 Major in Chemistry < PLO 1,2,3,4,5,6 > 2025 Major in Chemistry (Intensive) < PLO 1,2,3,4,5,6 > 2024 Major in Chemistry < PLO 1,2,3,4,5,6 > 2024 Major in Chemistry (Intensive) < PLO 1,2,3,4,5,6 > 2023 Major in Chemistry < PLO 1,2,3,4,5,6 > 2023 Major in Chemistry (Intensive) < PLO 1,2,3,4,5,6 > 2022 Major in Chemistry < PLO 1,2,3,4,5,6 > 2022 Major in Chemistry (Intensive) < PLO 1,2,3,4,5,6 > 2021 Major in Chemistry < PLO 1,2,3,4,5,6 > 2021 Major in Chemistry (Intensive) < PLO 1,2,3,4,5,6 >
Offer in 2025 - 2026	Y        Year long	Examination	No Exam
Offer in 2026 - 2027	Y
Course Grade	A+ to F
Grade Descriptors	A Show an extensive comprehension of the research project. Demonstrate very able analytical and critical thought with presence of some originality. Illuminating utilization and critical analysis / evaluation of information acquired from a wide range of high quality sources. Critical employment of data and results to synthesize appropriate and illuminating conclusions. Demonstrate integration of a wide range of appropriate theories, principles, data and methods. Employ very effective organizational and presentational skills. [Work of A+ should demonstrate substantial additional work beyond that is required in wider areas relevant to the topic.] B Show a substantial comprehension of the research project. Demonstrate able analytical and critical thinking with use of relevant information from sources. Demonstrate ability to compose meaningful comparisons between different secondary interpretations. Correct utilization of data and results to form appropriate conclusions. Compose general integration of theories, principles, data and methods. Perform effective organizational and presentational skills. C Show a general but incomplete comprehension of the research project. Presence of some analytical and critical thinking with use of relevant information from sources. Demonstrate ability to compose comparisons between different interpretations. Mainly correct but some incorrect utilization of data and results to form appropriate conclusions. Demonstrate some partial integration of theories, principles, data and methods. Perform moderately effective organizational and presentational skills. D Show a partial but limited comprehension, with knowledge of some relevant information, of the research project. Presence of some coherent and logical thinking, but with limited analytical and critical abilities. Show utilization and reference of several sources, but mostly via summary instead of by analysis and comparison. Limited ability to employ data and results to form appropriate conclusions. Demonstrate limited integration of theories, principles, data and methods. Perform limited or marginally effective organizational and presentational skills. Fail Show little or no comprehension of the research project. Evidence of little or lack of analytical and critical abilities, logical and coherent thinking. Limited employment of secondary sources and no critical comparison of them. Incorrectly utilize data and results and/or unable to form appropriate conclusions. Demonstrate little or no integration of theories, principles, data and methods. Organization and presentational skills are of very limited use or ineffective.
Communication-intensive Course	N
Course Type	Project-based course
Course Teaching & Learning Activities	Activities Details No. of Hours Reading / Self study 8 hours per week for 24 weeks or longer discussions & meetings 192.0
Assessment Methods and Weighting	Methods Details Weighting in final course grade (%) Assessment Methods to CLO Mapping Dissertation 50% Research (experiment and study in a research group); 30% Dissertation (written report) 80.0 1,2,3,4,5 Oral presentation 20.0 1,2,3,4,5
Required/recommended reading and online materials	Specialist texts dependant on the selected topic.
Course Website	NIL
Additional Course Information	Third year students with exceptional academic achievement may also apply for this course

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