Offered to students admitted to Year 1 in ALL
Major/Minor ALL
Course Type
Offer in 2021 - 2022 Y N
Course Code BIOC4612
Date2022/05/17 16:33
Enquiry for Course Details
BIOC4612 Molecular biology of the gene (6 credits) Academic Year 2021
Offering Department Biomedical Sciences Quota 50
Course Co-ordinator Prof K S E Cheah, Biomedical Sciences < hrmbdkc@hku.hk >
Teachers Involved (Dr K M Yao,Biomedical Sciences)
(Prof K S E Cheah,Biomedical Sciences)
(Prof. PT Liu,Biomedical Sciences)
(Prof. ZJ Zhou,Biomedical Sciences)
Course Objectives To provide an up-to-date knowledge of molecular biology, especially with respect to the regulation of eukaryotic gene expression.
Course Contents & Topics This is a comprehensive course covering many detailed molecular aspects of gene regulation and gene function.  Through this course an understanding of how gene expression can be regulated at levels of transcription and post transcription will be gained.
Course Learning Outcomes
On successful completion of this course, students should be able to:

CLO 1 describe the mechanisms for regulation of transcription, RNA processing and translation in eukaryotes
CLO 2 explain how cellular homeostasis can be maintained by a combination of controls of gene expression at multiple levels
CLO 3 illustrate the hierarchy of gene expression regulation in stem cells and developmental processes
CLO 4 interpret experimental results in gene regulation studies
CLO 5 work effectively with classmates in tutorial classes
Pre-requisites
(and Co-requisites and
Impermissible combinations)
Pass in BIOC3601 or BIOL3401 or BIOL3402 or BIOL3404 or BBMS2007
Course Status with Related Major/Minor /Professional Core 2021 Major in Biochemistry ( Disciplinary Elective )
2021 Minor in Biochemistry ( Disciplinary Elective )
2020 Major in Biochemistry ( Disciplinary Elective )
2020 Minor in Biochemistry ( Disciplinary Elective )
2019 Major in Biochemistry ( Disciplinary Elective )
2019 Minor in Biochemistry ( Disciplinary Elective )
2018 Major in Biochemistry ( Disciplinary Elective )
2018 Minor in Biochemistry ( Disciplinary Elective )
2017 Major in Biochemistry ( Disciplinary Elective )
2017 Minor in Biochemistry ( Disciplinary Elective )
Course to PLO Mapping 2021 Major in Biochemistry < PLO 1,2,3,4 >
2020 Major in Biochemistry < PLO 1,2,3,4 >
2019 Major in Biochemistry < PLO 1,2,3,4,5 >
2018 Major in Biochemistry < PLO 1,2,3,4,5 >
2017 Major in Biochemistry < PLO 1,2,3,4,5 >
Offer in 2021 - 2022 Y        2nd sem    Examination May     
Offer in 2022 - 2023 Y
Course Grade A+ to F
Grade Descriptors
A Demonstrates a deep and comprehensive understanding of the regulation of eukaryotic gene expression and its relevance to disease and effectively relates the knowledge to developmental processes. Uses skill and insight to analyse and interpret experimental data from gene regulation studies.
B Demonstrates a competent grasp of the key concepts in the regulation of eukaryotic gene expression and its relevance to disease and is able to link the knowledge to developmental processes. Correctly analyses and interprets experimental data from gene regulation studies.
C Demonstrates a basic understanding of the regulation of eukaryotic gene expression and its relevance to disease and is sometimes able to relate the knowledge to developmental processes. Displays a limited capacity to analyse and interpret experimental data from gene regulation studies.
D Demonstrates a simplistic knowledge of the regulation of eukaryotic gene expression and rarely relates the information to developmental processes. Displays weak analytical skills and is rarely able to interpret experimental data from gene regulation studies.
Fail Demonstrates incomplete or incorrect knowledge of the regulation of gene expression and is unable to relate the ideas to developmental processes. Unable to analyse or interpret experimental data from gene regulation studies.
Course Type Lecture-based course
Course Teaching
& Learning Activities
Activities Details No. of Hours
Lectures 36
Tutorials 12
Reading / Self study 100
Assessment Methods
and Weighting
Methods Details Weighting in final
course grade (%)
Assessment Methods
to CLO Mapping
Assignments 30 CLO 1,2,3,4,5
Examination 70 CLO 1,2,3,4
Required/recommended reading
and online materials
Alberts B et al. (2014) Molecular Biology of the Cell, 6th ed. Garland Science, New York.
Watson JD et al. (2014) Molecular Biology of the Gene, 7th ed. Pearson/Benjamin Cummings, San Francisco.
Course Website NIL
Additional Course Information NIL
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